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Tag Content
iUUCD ID IUUC-Ate-010248
Ensembl Protein ID CADATEAP00006501
UniProt Accession Q0CHM0; SEC13_ASPTN
Genbank Protein ID EAU33358.1
Protein Name Protein transport protein sec13
Genbank Nucleotide ID CH476602
Gene Name ATEG_06814; sec13
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CADATEAG00006501 CADATEAT00006501 CADATEAP00006501
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 9.10e-31 103.7 55 87
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
           gH++ v+c+a+  +   t+l+s+s+Dg++ +W+
   Q: 55   GHEGAVWCVAWahPKfgTILASSSYDGKVLIWR 87
           8***********9555599*************8 PP
   
Organism Aspergillus terreus
Functional Description
(View)

Functional Description


     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
 Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Sec13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MAAAQVISNS GHEDMIHDAG LDYYGRRLAT CSSDKTIKVF EIEGEAHRLV ETLKGHEGAV 60
WCVAWAHPKF GTILASSSYD GKVLIWREQH QNTTSPAAGS AWTKVFDFSL HTASVNMVSW 120
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Protein Fasta Sequence


>IUUC-Ate-010248|E3,WD_repeat|Aspergillus terreus
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Nucleotide Sequence
(Fasta)
ATGGTGTGTT TGGCCCCTTA AGTCGTTCCT GGTCCGCTCT CTAACCACGC GGGGATACAG 60
GCGGCGGCTC AGGTTATCTC CAACTCTGGC CATGAGGATA TGATTGTATG TATTACCGGT 120
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Nucleotide Fasta Sequence


>IUUC-Ate-010248|E3,WD_repeat|Aspergillus terreus
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0030127--C:COPII vesicle coat
GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0031080--C:nuclear pore outer ring
GO:0035859--C:Seh1-associated complex
GO:0005198--F:structural molecule activity
GO:0090114--P:COPII-coated vesicle budding
GO:0051028--P:mRNA transport
GO:0031081--P:nuclear pore distribution
GO:0043547--P:positive regulation of GTPase activity
GO:1904263--P:positive regulation of TORC1 signaling
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0015031--P:protein transport
GO:0030433--P:ubiquitin-dependent ERAD pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 48.53 2.00e-78 283.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.16 9.00e-83 298.00
IUUC-Atr-002914 Amborella trichopoda 49.50 2.00e-79 286.00
IUUC-Apl-003992 Anas platyrhynchos 50.50 9.00e-81 291.00
IUUC-Aca-005283 Anolis carolinensis 50.16 1.00e-83 301.00
IUUC-Aly-005654 Arabidopsis lyrata 47.23 1.00e-72 264.00
IUUC-Ath-006816 Arabidopsis thaliana 46.91 5.00e-72 262.00
IUUC-Ago-007827 Ashbya gossypii 56.09 1.00e-96 344.00
IUUC-Acl-008205 Aspergillus clavatus 95.93 6.00e-171 591.00
IUUC-Afl-008748 Aspergillus flavus 94.82 3.00e-177 611.00
IUUC-Afu-008791 Aspergillus fumigatus 95.25 4.00e-170 588.00
IUUC-Ani-009152 Aspergillus nidulans 90.61 5.00e-171 591.00
IUUC-Ang-009765 Aspergillus niger 95.11 1.00e-176 610.00
IUUC-Aor-009927 Aspergillus oryzae 94.90 2.00e-168 582.00
IUUC-Ame-011478 Astyanax mexicanus 51.14 3.00e-85 306.00
IUUC-Bgr-012276 Blumeria graminis 66.98 1.00e-125 440.00
IUUC-Bta-012700 Bos taurus 50.16 4.00e-82 296.00
IUUC-Bci-013722 Botrytis cinerea 70.32 4.00e-129 452.00
IUUC-Bdi-014818 Brachypodium distachyon 48.86 3.00e-78 283.00
IUUC-Bol-015779 Brassica oleracea 47.23 4.00e-72 263.00
IUUC-Bra-016973 Brassica rapa 46.73 2.00e-72 265.00
IUUC-Cel-018479 Caenorhabditis elegans 38.94 1.00e-59 221.00
IUUC-Cja-019956 Callithrix jacchus 50.69 2.00e-76 277.00
IUUC-Cfa-020752 Canis familiaris 50.16 1.00e-82 298.00
IUUC-Cpo-021871 Cavia porcellus 50.81 1.00e-83 301.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 49.50 6.00e-78 282.00
IUUC-Csa-023393 Chlorocebus sabaeus 50.81 3.00e-83 300.00
IUUC-Cho-024786 Choloepus hoffmanni 58.00 1.00e-26 112.00
IUUC-Cin-025332 Ciona intestinalis 53.27 2.00e-86 310.00
IUUC-Csv-025926 Ciona savignyi 53.29 4.00e-86 309.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 70.13 1.00e-116 410.00
IUUC-Cne-027054 Cryptococcus neoformans 51.84 9.00e-80 288.00
IUUC-Cme-027165 Cyanidioschyzon merolae 36.31 2.00e-49 188.00
IUUC-Dre-027782 Danio rerio 51.79 4.00e-85 305.00
IUUC-Dno-029628 Dasypus novemcinctus 49.84 1.00e-82 297.00
IUUC-Dor-030650 Dipodomys ordii 48.74 4.00e-60 223.00
IUUC-Dse-031206 Dothistroma septosporum 67.73 2.00e-121 426.00
IUUC-Dme-031854 Drosophila melanogaster 50.00 6.00e-75 272.00
IUUC-Ete-032618 Echinops telfairi 42.35 2.00e-36 144.00
IUUC-Eca-033268 Equus caballus 50.16 2.00e-82 297.00
IUUC-Fca-035918 Felis catus 50.16 2.00e-82 297.00
IUUC-Fal-037551 Ficedula albicollis 50.50 7.00e-77 278.00
IUUC-Fox-037763 Fusarium oxysporum 70.65 3.00e-131 459.00
IUUC-Fso-038341 Fusarium solani 70.29 1.00e-129 453.00
IUUC-Gmo-038638 Gadus morhua 50.49 3.00e-84 303.00
IUUC-Ggr-039865 Gaeumannomyces graminis 70.42 2.00e-128 449.00
IUUC-Gga-040193 Gallus gallus 50.81 2.00e-84 303.00
IUUC-Gac-041337 Gasterosteus aculeatus 34.48 7.00e-36 142.00
IUUC-Gma-044311 Glycine max 49.50 2.00e-77 280.00
IUUC-Ggo-045252 Gorilla gorilla 50.81 2.00e-83 300.00
IUUC-Hsa-046565 Homo sapiens 50.81 3.00e-83 300.00
IUUC-Hvu-047835 Hordeum vulgare 49.51 1.00e-78 284.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 50.49 7.00e-83 298.00
IUUC-Kpa-049148 Komagataella pastoris 58.12 6.00e-98 348.00
IUUC-Lch-050421 Latimeria chalumnae 52.44 2.00e-86 310.00
IUUC-Lpe-051187 Leersia perrieri 47.12 1.00e-77 283.00
IUUC-Loc-052167 Lepisosteus oculatus 50.49 1.00e-85 307.00
IUUC-Lma-053250 Leptosphaeria maculans 69.06 6.00e-123 431.00
IUUC-Laf-054304 Loxodonta africana 50.16 4.00e-83 299.00
IUUC-Mcc-055519 Macaca mulatta 50.81 4.00e-83 299.00
IUUC-Meu-056439 Macropus eugenii 50.16 9.00e-84 301.00
IUUC-Mor-057241 Magnaporthe oryzae 71.14 2.00e-125 439.00
IUUC-Mpo-057373 Magnaporthe poae 62.75 2.00e-106 375.00
IUUC-Mtr-058412 Medicago truncatula 48.18 1.00e-75 274.00
IUUC-Mla-058966 Melampsora laricipopulina 52.89 6.00e-92 328.00
IUUC-Mga-060066 Meleagris gallopavo 50.50 9.00e-81 291.00
IUUC-Mvi-060290 Microbotryum violaceum 53.41 1.00e-90 327.00
IUUC-Mmr-060717 Microcebus murinus 50.49 3.00e-83 299.00
IUUC-Mdo-062496 Monodelphis domestica 49.84 1.00e-83 301.00
IUUC-Mmu-063490 Mus musculus 49.52 3.00e-83 299.00
IUUC-Mac-064519 Musa acuminata 47.52 1.00e-74 271.00
IUUC-Mpu-066601 Mustela putorius furo 50.16 1.00e-82 298.00
IUUC-Mlu-067501 Myotis lucifugus 50.16 1.00e-82 298.00
IUUC-Nfi-068360 Neosartorya fischeri 96.11 2.00e-147 512.00
IUUC-Ncr-068928 Neurospora crassa 73.31 4.00e-136 475.00
IUUC-Nle-069028 Nomascus leucogenys 50.49 3.00e-83 300.00
IUUC-Opr-070446 Ochotona princeps 50.17 6.00e-79 285.00
IUUC-Ont-071587 Oreochromis niloticus 52.44 6.00e-87 311.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.19 2.00e-82 297.00
IUUC-Ocu-074306 Oryctolagus cuniculus 51.47 4.00e-84 302.00
IUUC-Oba-075069 Oryza barthii 48.21 5.00e-77 279.00
IUUC-Obr-076667 Oryza brachyantha 48.86 6.00e-78 282.00
IUUC-Ogl-077208 Oryza glaberrima 48.21 5.00e-77 279.00
IUUC-Ogu-078513 Oryza glumaepatula 48.21 5.00e-77 279.00
IUUC-Oin-079094 Oryza indica 48.21 5.00e-77 279.00
IUUC-Olo-080473 Oryza longistaminata 48.21 5.00e-77 279.00
IUUC-Ome-081643 Oryza meridionalis 48.21 5.00e-77 279.00
IUUC-Oni-082589 Oryza nivara 48.21 5.00e-77 279.00
IUUC-Opu-083677 Oryza punctata 48.04 6.00e-77 278.00
IUUC-Oru-084537 Oryza rufipogon 48.21 5.00e-77 279.00
IUUC-Osa-085449 Oryza sativa 48.21 5.00e-77 279.00
IUUC-Ola-087226 Oryzias latipes 52.12 1.00e-86 310.00
IUUC-Olu-087893 Ostreococcus lucimarinus 48.67 2.00e-67 247.00
IUUC-Oga-088837 Otolemur garnettii 50.16 8.00e-83 298.00
IUUC-Oar-089594 Ovis aries 50.49 2.00e-82 296.00
IUUC-Ptr-091132 Pan troglodytes 50.81 2.00e-83 300.00
IUUC-Pan-092013 Papio anubis 33.20 4.00e-28 116.00
IUUC-Psi-093568 Pelodiscus sinensis 50.50 6.00e-82 295.00
IUUC-Pma-094172 Petromyzon marinus 47.44 3.00e-33 132.00
IUUC-Pno-094955 Phaeosphaeria nodorum 68.01 7.00e-117 411.00
IUUC-Ppa-095835 Physcomitrella patens 49.68 1.00e-77 281.00
IUUC-Pfo-096063 Poecilia formosa 52.77 8.00e-87 311.00
IUUC-Pab-098674 Pongo abelii 50.49 2.00e-82 296.00
IUUC-Pop-099402 Populus trichocarpa 46.86 2.00e-73 267.00
IUUC-Pca-100824 Procavia capensis 37.58 3.00e-57 213.00
IUUC-Ppe-101707 Prunus persica 46.96 1.00e-73 268.00
IUUC-Pva-103161 Pteropus vampyrus 46.25 5.00e-75 272.00
IUUC-Pgr-103573 Puccinia graminis 53.14 6.00e-92 328.00
IUUC-Ptt-103700 Puccinia triticina 50.80 9.00e-87 311.00
IUUC-Pte-104267 Pyrenophora teres 66.11 8.00e-113 397.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 66.44 4.00e-107 379.00
IUUC-Rno-104833 Rattus norvegicus 50.49 6.00e-83 298.00
IUUC-Sce-106437 Saccharomyces cerevisiae 58.77 1.00e-94 337.00
IUUC-Sha-106611 Sarcophilus harrisii 50.16 9.00e-84 301.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 54.61 5.00e-91 325.00
IUUC-Spo-108362 Schizosaccharomyces pombe 54.30 4.00e-88 315.00
IUUC-Smo-108797 Selaginella moellendorffii 49.18 4.00e-76 276.00
IUUC-Sit-110132 Setaria italica 49.02 3.00e-78 283.00
IUUC-Sly-111852 Solanum lycopersicum 47.54 1.00e-72 264.00
IUUC-Stu-112195 Solanum tuberosum 48.20 9.00e-74 268.00
IUUC-Sar-113279 Sorex araneus 31.60 2.00e-24 104.00
IUUC-Sbi-114229 Sorghum bicolor 50.33 1.00e-79 287.00
IUUC-Sre-114898 Sporisorium reilianum 49.13 2.00e-86 310.00
IUUC-Ssc-115995 Sus scrofa 51.11 7.00e-39 150.00
IUUC-Tgu-116793 Taeniopygia guttata 50.49 4.00e-79 285.00
IUUC-Tru-117797 Takifugu rubripes 51.47 8.00e-86 308.00
IUUC-Tsy-118913 Tarsius syrichta 31.46 4.00e-22 96.70
IUUC-Tni-120366 Tetraodon nigroviridis 52.77 1.00e-87 314.00
IUUC-Tca-121068 Theobroma cacao 47.16 2.00e-73 267.00
IUUC-Tre-121899 Trichoderma reesei 70.32 7.00e-130 454.00
IUUC-Tvi-122380 Trichoderma virens 71.29 3.00e-131 459.00
IUUC-Tae-123998 Triticum aestivum 49.51 2.00e-79 287.00
IUUC-Tur-126202 Triticum urartu 49.19 1.00e-78 284.00
IUUC-Tme-127181 Tuber melanosporum 59.55 2.00e-106 377.00
IUUC-Ttr-128448 Tursiops truncatus 49.23 6.00e-64 236.00
IUUC-Uma-129661 Ustilago maydis 49.71 1.00e-86 310.00
IUUC-Vda-129666 Verticillium dahliae 70.13 5.00e-120 421.00
IUUC-Vpa-130318 Vicugna pacos 50.16 2.00e-82 297.00
IUUC-Vvi-130868 Vitis vinifera 48.51 1.00e-76 277.00
IUUC-Xtr-131859 Xenopus tropicalis 50.81 5.00e-85 305.00
IUUC-Xma-133898 Xiphophorus maculatus 52.44 1.00e-86 310.00
IUUC-Yli-134559 Yarrowia lipolytica 60.47 3.00e-99 353.00
Created Date 25-Jun-2017

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