iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000027983.2	ENSGALT00000043485.2	ENSGALP00000042503.2
ENSGALG00000027983.2	ENSGALT00000067422.1	ENSGALP00000054783.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	68.66	0.00e+00	1299.00	IUUC-Hsa-046670

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPPPMPPPPR SATGGDTQAA ELGGEQQCHA TFCHVIPCPA PALAAPRQAQ SPPPAAAAMG 60
ERCDYQRLSS AEEEEEMLPP LPHSLSDSSG LRAPRMGSSR PGLPPQQDVT LGMACRRKLS 120

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Nucleotide Sequence
(Fasta)

ATGCCACCGC CGATGCCCCC GCCTCCACGC TCGGCTACCG GGGGGGACAC GCAGGCTGCG 60
GAGCTGGGAG GAGAACAGCA GTGCCACGGT GAGGACGGGT ACCTGGGGGG CTCCCCGTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR015116--Cdc42_binding_dom-like
IPR011009--Kinase-like_dom
IPR021619--Mig-6
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
IPR009060--UBA-like

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50002--SH3

Pfam

PF09027--GTPase_binding
PF11555--Inhibitor_Mig-6
PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00109--TYRKINASE

SMART

SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030136--C:clathrin-coated vesicle
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0070436--C:Grb2-EGFR complex
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0004712--F:protein serine/threonine/tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0050731--P:positive regulation of peptidyl-tyrosine phosphorylation
GO:0042127--P:regulation of cell proliferation
GO:2000369--P:regulation of clathrin-dependent endocytosis
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002166	Ailuropoda melanoleuca	66.79	0.00e+00	1234.00
IUUC-Aca-004315	Anolis carolinensis	94.12	9.00e-78	281.00
IUUC-Ame-011350	Astyanax mexicanus	55.38	0.00e+00	1064.00
IUUC-Bta-012325	Bos taurus	68.66	0.00e+00	1274.00
IUUC-Cel-018130	Caenorhabditis elegans	39.16	8.00e-92	332.00
IUUC-Cja-019545	Callithrix jacchus	63.81	0.00e+00	1177.00
IUUC-Cfa-020706	Canis familiaris	68.59	0.00e+00	1286.00
IUUC-Cpo-022032	Cavia porcellus	66.38	0.00e+00	1223.00
IUUC-Csa-023936	Chlorocebus sabaeus	66.64	0.00e+00	1250.00
IUUC-Csv-026328	Ciona savignyi	59.53	9.00e-165	573.00
IUUC-Dre-028714	Danio rerio	66.51	0.00e+00	1332.00
IUUC-Dno-029525	Dasypus novemcinctus	68.73	0.00e+00	1281.00
IUUC-Dme-031778	Drosophila melanogaster	54.79	4.00e-135	475.00
IUUC-Ete-032225	Echinops telfairi	76.66	0.00e+00	689.00
IUUC-Fca-035664	Felis catus	68.83	0.00e+00	1293.00
IUUC-Gmo-039543	Gadus morhua	57.41	0.00e+00	932.00
IUUC-Gac-041457	Gasterosteus aculeatus	63.64	0.00e+00	1165.00
IUUC-Ggo-045333	Gorilla gorilla	73.34	0.00e+00	1030.00
IUUC-Hsa-046670	Homo sapiens	74.97	0.00e+00	1044.00
IUUC-Itr-048054	Ictidomys tridecemlineatus	68.83	0.00e+00	1273.00
IUUC-Lch-049670	Latimeria chalumnae	70.17	0.00e+00	1415.00
IUUC-Loc-052870	Lepisosteus oculatus	71.56	0.00e+00	1451.00
IUUC-Laf-053782	Loxodonta africana	66.67	0.00e+00	1228.00
IUUC-Mcc-055874	Macaca mulatta	66.88	0.00e+00	1237.00
IUUC-Mga-059717	Meleagris gallopavo	95.62	0.00e+00	1919.00
IUUC-Mdo-062270	Monodelphis domestica	65.84	0.00e+00	1260.00
IUUC-Mmu-063861	Mus musculus	68.49	0.00e+00	1287.00
IUUC-Mpu-066127	Mustela putorius furo	70.70	0.00e+00	1048.00
IUUC-Mlu-067937	Myotis lucifugus	65.27	0.00e+00	1243.00
IUUC-Nle-069298	Nomascus leucogenys	76.19	0.00e+00	878.00
IUUC-Ont-072437	Oreochromis niloticus	63.82	0.00e+00	1287.00
IUUC-Oan-073708	Ornithorhynchus anatinus	64.65	2.00e-102	366.00
IUUC-Ola-087023	Oryzias latipes	63.60	0.00e+00	1174.00
IUUC-Pan-091857	Papio anubis	57.46	6.00e-64	236.00
IUUC-Psi-093401	Pelodiscus sinensis	55.10	2.00e-137	483.00
IUUC-Pfo-097455	Poecilia formosa	60.84	0.00e+00	1269.00
IUUC-Rno-105586	Rattus norvegicus	66.23	0.00e+00	1273.00
IUUC-Sha-106868	Sarcophilus harrisii	74.76	0.00e+00	1061.00
IUUC-Ssc-116250	Sus scrofa	68.11	0.00e+00	1258.00
IUUC-Tgu-116592	Taeniopygia guttata	84.48	0.00e+00	1651.00
IUUC-Tru-117852	Takifugu rubripes	68.83	2.00e-174	607.00
IUUC-Tsy-119087	Tarsius syrichta	70.03	3.00e-153	535.00
IUUC-Tni-120826	Tetraodon nigroviridis	64.04	0.00e+00	1301.00
IUUC-Xtr-132069	Xenopus tropicalis	77.50	0.00e+00	1404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence