iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011806

Ensembl Protein ID

ENSAMXP00000004010.1

UniProt Accession

W5K8U9; W5K8U9_ASTMX

Genbank Protein ID

ENSAMXP00000004010

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

APWO01004796

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000003923.1	ENSAMXT00000004010.1	ENSAMXP00000004010.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	68.16	1.00e-84	309.00	IUUC-Hsa-045820
DUB/UCH	68.16	1.00e-84	309.00	IUUC-Hsa-045820
UBD/Other/Other	68.16	1.00e-84	309.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MEWKPMEINP EMLNKVLGKL GVGADWHFVD VLGLEDEALS GVPTPCCALM LLFPLTQQHE 60
QFRSSQSVDG SKDVYFLNQT VVNSCGTVGL LHAVANNQDK MTFEAGSTLK KFLEETTGMS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGTGGGCT CTACTGGCAG CTTCTAGAAA CATCATCTGA CTGTGGAGCG GTCTATTCCT 60
GCAGCGCGTG CGCGGCGCGT GCTGGCTGTT ATGATTTAAA ATTTGGCGAA AAGTCCGTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005622--C:intracellular
GO:0016874--F:ligase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	55.64	4.00e-71	260.00
IUUC-Apl-003693	Anas platyrhynchos	56.95	8.00e-71	259.00
IUUC-Aca-004716	Anolis carolinensis	63.23	7.00e-84	303.00
IUUC-Bta-013521	Bos taurus	55.95	8.00e-72	263.00
IUUC-Cja-019642	Callithrix jacchus	67.26	2.00e-75	275.00
IUUC-Cfa-020442	Canis familiaris	66.96	5.00e-75	273.00
IUUC-Csa-023626	Chlorocebus sabaeus	68.16	1.00e-76	278.00
IUUC-Cho-024548	Choloepus hoffmanni	56.48	1.00e-21	96.30
IUUC-Dre-027854	Danio rerio	80.28	6.00e-107	379.00
IUUC-Dno-029325	Dasypus novemcinctus	67.26	6.00e-76	276.00
IUUC-Dor-030114	Dipodomys ordii	67.26	5.00e-85	306.00
IUUC-Ete-033092	Echinops telfairi	54.26	2.00e-61	228.00
IUUC-Eeu-034493	Erinaceus europaeus	65.02	1.00e-72	265.00
IUUC-Fal-036693	Ficedula albicollis	63.16	4.00e-77	280.00
IUUC-Gmo-038848	Gadus morhua	70.81	7.00e-89	319.00
IUUC-Gga-041078	Gallus gallus	63.23	3.00e-84	304.00
IUUC-Gac-042064	Gasterosteus aculeatus	72.81	2.00e-94	337.00
IUUC-Ggo-044827	Gorilla gorilla	68.16	5.00e-77	280.00
IUUC-Hsa-045820	Homo sapiens	68.16	5.00e-77	280.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	66.82	2.00e-75	274.00
IUUC-Lch-050121	Latimeria chalumnae	65.32	4.00e-84	304.00
IUUC-Loc-052342	Lepisosteus oculatus	72.32	2.00e-95	341.00
IUUC-Laf-053916	Loxodonta africana	67.56	1.00e-76	279.00
IUUC-Mcc-054838	Macaca mulatta	68.16	1.00e-76	278.00
IUUC-Meu-056478	Macropus eugenii	65.47	4.00e-84	303.00
IUUC-Mga-059878	Meleagris gallopavo	61.11	8.00e-77	279.00
IUUC-Mdo-062544	Monodelphis domestica	64.86	2.00e-73	268.00
IUUC-Mmu-063300	Mus musculus	67.26	2.00e-85	308.00
IUUC-Mpu-066128	Mustela putorius furo	64.18	3.00e-63	234.00
IUUC-Mlu-067778	Myotis lucifugus	67.26	2.00e-85	308.00
IUUC-Nle-069686	Nomascus leucogenys	68.16	9.00e-77	279.00
IUUC-Opr-070535	Ochotona princeps	55.61	8.00e-63	233.00
IUUC-Ont-071510	Oreochromis niloticus	74.89	4.00e-99	353.00
IUUC-Ocu-074590	Oryctolagus cuniculus	67.26	1.00e-75	275.00
IUUC-Ola-087552	Oryzias latipes	69.33	4.00e-90	323.00
IUUC-Oga-089013	Otolemur garnettii	56.75	8.00e-72	263.00
IUUC-Oar-089861	Ovis aries	56.75	7.00e-72	263.00
IUUC-Ptr-091536	Pan troglodytes	66.37	1.00e-74	272.00
IUUC-Pan-092909	Papio anubis	68.16	1.00e-76	278.00
IUUC-Psi-093818	Pelodiscus sinensis	65.47	4.00e-86	310.00
IUUC-Pfo-097335	Poecilia formosa	68.02	2.00e-89	321.00
IUUC-Pab-098048	Pongo abelii	68.16	5.00e-77	280.00
IUUC-Pca-100818	Procavia capensis	47.94	8.00e-37	146.00
IUUC-Pva-102954	Pteropus vampyrus	67.26	2.00e-73	268.00
IUUC-Pyt-104587	Pyrenophora triticirepentis	35.58	7.00e-28	117.00
IUUC-Rno-105966	Rattus norvegicus	67.26	2.00e-85	308.00
IUUC-Spo-108322	Schizosaccharomyces pombe	30.63	1.00e-24	106.00
IUUC-Sar-113190	Sorex araneus	53.98	1.00e-23	100.00
IUUC-Ssc-115908	Sus scrofa	56.44	8.00e-66	243.00
IUUC-Tgu-117465	Taeniopygia guttata	60.48	2.00e-72	264.00
IUUC-Tru-118565	Takifugu rubripes	67.27	9.00e-82	295.00
IUUC-Tsy-119561	Tarsius syrichta	54.71	1.00e-60	225.00
IUUC-Tbe-128048	Tupaia belangeri	64.24	4.00e-57	213.00
IUUC-Ttr-128494	Tursiops truncatus	65.02	3.00e-72	264.00
IUUC-Xtr-132286	Xenopus tropicalis	64.41	9.00e-82	295.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence