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Tag Content
iUUCD ID IUUC-Dre-028508
Ensembl Protein ID ENSDARP00000027753.10
UniProt Accession F1QEQ5; F1QEQ5_DANRE
Genbank Protein ID ENSDARP00000027753
Protein Name Bromodomain and WD repeat domain-containing 3
Genbank Nucleotide ID CR762398
Gene Name brwd3; si:dkey-237j10.3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000035540.7 ENSDART00000147157.2 ENSDARP00000114236.2
ENSDARG00000035540.7 ENSDART00000020434.10 ENSDARP00000027753.10
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 6.70e-29 99.6 179 216
UBD/Beta-Prp 5.70e-51 174.4 281 536
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  + +++ +GsdD+ +k+W ++ g+ll
   Q: 179  GHLSSVYCVAFdRTgRRIFTGSDDCLVKIWATDNGRLL 216
           8**********955599**************9999886 PP
   

   UBD/Beta-Prp
   S: 22   ksllatgsrdgtikvwdvttgkl......lrslsgheae..vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvls 99
           +++lat+++dg++  w++ + ++      ++ ++   ++  +++ +fs+ g +l+tg++D++i+v+    + +  ++ l  h+d+v++
   Q: 281  SRFLATTGADGMVCFWQWNSFSMkfvdkpVKFMERSRPGvqISCSSFSSGGLFLATGGTDHMIRVYylGTEMPVKFSDLDSHTDKVVA 368
           689************99999666667776555555555466899**********************44444555677899******** PP
   S: 100  lsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
           ++f+ ++   ++vsGs+d t+r+w+ +++++ ++                 ++ ++ vv++v+++  ++ ++++  +  +++W++ +g
   Q: 369  IQFCNNTdsLRFVSGSRDGTARIWHYQQQEWKSTvldmttrlpgsavisgDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNG 456
           *****6623579********************99************99977778888999******99******************** PP
   S: 170  kllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDg 244
           +ll+ l+g h+d v  l+   fds  + l+s+++dg + +wdl++g+ +r + +         v + +fs ++++++++ s+g
   Q: 457  QLLHVLSG-HDDEVFVLEahpFDS--RILLSAGHDGNIYVWDLSKGQKIRNFFNMIegqghGAVFDCKFSVDGQHFACTDSHG 536
           *******9.*********655555..9*********************88887644333334455555555666666666555 PP
   
Organism Danio rerio
Protein Sequence
(Fasta)
MAAEPCSQIE AELYYLIARF LQSGPCQKSA QMLLQELHEY EIIPKRWSWD GEQFKRSFDD 60
WVLLNQHIPA DYLLRVCKEV GPLIDKHIPP SVPGVHSLLG TGRQSLLRTA KSSSHTLWSG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028508|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AACCGCGCGG GGGCGCTCAA ACAAAGCAGC ACGAGCGGCG GCTGCAGGCC GAAACGCTGA 60
GAGCAAATAC AACACAGGCC GCTCTTAGCA AGCAGAGCCC CGTGAACCTC CACCCACCGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028508|E3,WD_repeat;UBD,Beta-Prp|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00439--Bromodomain
PF00400--WD40
PRINTS

PR00503--BROMODOMAIN
SMART

SM00297--BROMO
SM00320--WD40
KEGG dre:553209
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001881 Ailuropoda melanoleuca 66.80 0.00e+00 1930.00
IUUC-Apl-004016 Anas platyrhynchos 66.09 0.00e+00 1786.00
IUUC-Aca-004722 Anolis carolinensis 69.84 0.00e+00 1731.00
IUUC-Ame-010602 Astyanax mexicanus 77.30 0.00e+00 2194.00
IUUC-Bta-013198 Bos taurus 66.94 0.00e+00 1748.00
IUUC-Cfa-020963 Canis familiaris 67.13 0.00e+00 1929.00
IUUC-Cpo-022448 Cavia porcellus 63.05 0.00e+00 1791.00
IUUC-Csa-023166 Chlorocebus sabaeus 67.03 0.00e+00 1924.00
IUUC-Dno-030070 Dasypus novemcinctus 65.20 0.00e+00 1842.00
IUUC-Ete-032650 Echinops telfairi 62.83 0.00e+00 1341.00
IUUC-Eca-033953 Equus caballus 67.50 0.00e+00 1711.00
IUUC-Eeu-034871 Erinaceus europaeus 61.37 0.00e+00 974.00
IUUC-Fca-036099 Felis catus 66.74 0.00e+00 1919.00
IUUC-Fal-037246 Ficedula albicollis 69.19 0.00e+00 1880.00
IUUC-Gmo-039116 Gadus morhua 72.52 0.00e+00 631.00
IUUC-Gga-041097 Gallus gallus 69.25 0.00e+00 1933.00
IUUC-Gac-042435 Gasterosteus aculeatus 70.79 0.00e+00 1998.00
IUUC-Hsa-045666 Homo sapiens 66.87 0.00e+00 1928.00
IUUC-Lch-050646 Latimeria chalumnae 58.88 0.00e+00 1712.00
IUUC-Loc-051802 Lepisosteus oculatus 70.70 0.00e+00 2100.00
IUUC-Laf-053942 Loxodonta africana 67.06 0.00e+00 1948.00
IUUC-Mcc-054645 Macaca mulatta 67.10 0.00e+00 1928.00
IUUC-Meu-056321 Macropus eugenii 60.55 0.00e+00 884.00
IUUC-Mtr-058094 Medicago truncatula 31.14 7.00e-71 263.00
IUUC-Mga-060063 Meleagris gallopavo 68.63 0.00e+00 1892.00
IUUC-Mmr-061262 Microcebus murinus 67.13 0.00e+00 1930.00
IUUC-Mdo-062320 Monodelphis domestica 61.19 0.00e+00 1691.00
IUUC-Mmu-063163 Mus musculus 65.32 0.00e+00 1914.00
IUUC-Mpu-066628 Mustela putorius furo 67.03 0.00e+00 1919.00
IUUC-Mlu-068082 Myotis lucifugus 67.08 0.00e+00 1903.00
IUUC-Nle-069609 Nomascus leucogenys 66.99 0.00e+00 1930.00
IUUC-Ont-071589 Oreochromis niloticus 71.26 0.00e+00 2003.00
IUUC-Oan-072954 Ornithorhynchus anatinus 59.67 0.00e+00 1707.00
IUUC-Ocu-074456 Oryctolagus cuniculus 60.28 0.00e+00 1705.00
IUUC-Ogu-078641 Oryza glumaepatula 26.14 2.00e-29 125.00
IUUC-Oin-079669 Oryza indica 32.50 2.00e-50 194.00
IUUC-Olo-080755 Oryza longistaminata 32.43 2.00e-51 198.00
IUUC-Oni-082991 Oryza nivara 26.14 2.00e-29 125.00
IUUC-Ola-086580 Oryzias latipes 70.09 0.00e+00 2045.00
IUUC-Oga-089053 Otolemur garnettii 67.36 0.00e+00 1933.00
IUUC-Oar-090042 Ovis aries 67.26 0.00e+00 1928.00
IUUC-Ptr-091268 Pan troglodytes 66.32 0.00e+00 1892.00
IUUC-Pan-092376 Papio anubis 67.10 0.00e+00 1928.00
IUUC-Psi-093408 Pelodiscus sinensis 65.23 0.00e+00 1884.00
IUUC-Pfo-096515 Poecilia formosa 73.42 0.00e+00 1947.00
IUUC-Pab-097672 Pongo abelii 65.52 0.00e+00 1882.00
IUUC-Pva-102512 Pteropus vampyrus 68.28 0.00e+00 1677.00
IUUC-Rno-105797 Rattus norvegicus 66.57 0.00e+00 1921.00
IUUC-Sha-107061 Sarcophilus harrisii 63.14 0.00e+00 1719.00
IUUC-Sar-113004 Sorex araneus 74.55 0.00e+00 880.00
IUUC-Ssc-115461 Sus scrofa 55.59 0.00e+00 1543.00
IUUC-Tgu-117254 Taeniopygia guttata 68.05 0.00e+00 1866.00
IUUC-Tru-118186 Takifugu rubripes 69.86 0.00e+00 1968.00
IUUC-Tsy-119003 Tarsius syrichta 62.16 0.00e+00 1709.00
IUUC-Tni-120110 Tetraodon nigroviridis 69.00 0.00e+00 1962.00
IUUC-Ttr-129265 Tursiops truncatus 66.60 0.00e+00 1856.00
IUUC-Xtr-132717 Xenopus tropicalis 57.79 0.00e+00 1672.00
Created Date 25-Jun-2017

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