iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Hsa-045818

Ensembl Protein ID

ENSP00000454445.2

UniProt Accession

H3BMM0; H3BMM0_HUMAN

Genbank Protein ID

ENSP00000454445

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AC022826

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000258677.2	ENST00000358757.5	ENSP00000454445.2

Annotation

Cancer Mutation
ICGC
mRNA Expression
ArrayExpress
DNA & RNA Element
miRNAMap
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	4.70e-36	125.3	7	141

Active Site

Position(s)	Description	Evidence
91	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdppegisakpvdesd.ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltk..ifhPnvyenGkvClsilkee 89
           Rl+kel +l++dpp+g++++ ++ ++ +t+w v ++G ++t Yeg++F+l ++f+++YPf++P+v+f+ +    hP+vy+nG++Clsil+  
   Q: 7    RLQKELLALQNDPPPGMTLNEKSVQNsITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQVMFTGEniPVHPHVYSNGHICLSILT-- 96
           9*********************99989*****************************************99989****************9.. PP
   S: 90   ekWspalsvesvllsiqsll..aepnpesplneeaaellkknree 132
           e+Wspalsv+sv+lsi+s+l  ++ + + p n+  +++++kn+++
   Q: 97   EDWSPALSVQSVCLSIISMLssCKEKRRPPDNSFYVRTCNKNPKK 141
           ********************6556777889999999999999874 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MASMQKRLQK ELLALQNDPP PGMTLNEKSV QNSITQWIVD MEGAPGTLYE GEKFQLLFKF 60
SSRYPFDSPQ VMFTGENIPV HPHVYSNGHI CLSILTEDWS PALSVQSVCL SIISMLSSCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTCGCCG GTCTTGGGGG GATGGTTCCA TCATGGCGTC AATGCAGGTG AGAGGAGTTT 60
GCTGCATCTG GGCGGGCCAG GGAGCCGCCG AGAGAGTGCC AGCGTTCGGG CGGGGGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003950	Anas platyrhynchos	96.60	4.00e-84	303.00
IUUC-Cho-024448	Choloepus hoffmanni	86.96	1.00e-66	244.00
IUUC-Eca-033939	Equus caballus	100.00	2.00e-83	300.00
IUUC-Fca-035457	Felis catus	93.55	1.00e-84	304.00
IUUC-Gac-041300	Gasterosteus aculeatus	96.55	2.00e-82	297.00
IUUC-Lch-050426	Latimeria chalumnae	92.99	9.00e-85	305.00
IUUC-Laf-053849	Loxodonta africana	100.00	2.00e-83	300.00
IUUC-Ocu-074009	Oryctolagus cuniculus	99.31	3.00e-84	303.00
IUUC-Ola-086845	Oryzias latipes	98.06	3.00e-58	215.00
IUUC-Oar-090149	Ovis aries	100.00	3.00e-84	303.00
IUUC-Pca-100346	Procavia capensis	100.00	4.00e-82	296.00
IUUC-Tsy-119222	Tarsius syrichta	99.31	4.00e-84	303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence