iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028692

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Josephin domain containing 1; Josephin domain-containing 1

Genbank Nucleotide ID

CU914479

Gene Name

josd1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000071548.4	ENSDART00000105854.4	ENSDARP00000096632.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/Josephin	1.70e-82	276.4	52	232

Active Site

Position(s)	Description	Evidence
69	N/A	{ECO:0000256\|PROSITE-ProRule:PRU00331}
172		{ECO:0000256\|PROSITE-ProRule:PRU00331}
187		{ECO:0000256\|PROSITE-ProRule:PRU00331}

Domain Profile

DUB/Josephin

   S: 7    aqaapesiyhekqrrelCalhalnnvlqd.elfsreeldeiakrldeeerlqPs.kslldtGnydvnvisaalkvlGleavwfdkrrel 93
           +   p+ iyhekq+relCalhalnnv+qd  +fsr++l++i +rl++ + ++P+ k++l++Gnydvnvi+aal+++G+eavw+dkrr++
   Q: 52   TSLQPPAIYHEKQHRELCALHALNNVFQDgAAFSRDALQDIYQRLSPSTLVTPHkKNMLGNGNYDVNVIMAALQTRGFEAVWWDKRRDV 140
           556799***********************99***********************99********************************* PP
   S: 94   qklaldnvlgfilnlpsslslgllklplkkqhWvtvrkvgkayynldsklkaPeligdetelrkflakllqqkyselllvvkeevedke 182
           + +al+nv gfiln+ps+l +g+l+lplk+qhW+ vr+v ++yynldskl++P +ig  +elrkfl+++l++k++elllvv+eeve ++
   Q: 141  GSIALPNVTGFILNVPSNLRWGPLRLPLKRQHWIGVREVAGVYYNLDSKLRSPHAIGTADELRKFLRHQLRGKNCELLLVVSEEVEVHQ 229
           ***************************************************************************************** PP
   S: 183  sdq 185
           +++
   Q: 230  TWK 232
           **6 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MGSTPCSGKG RGVGGFQELG CMPWKVSKQK GEALGGRGSE LEDRPNAGTP PTSLQPPAIY 60
HEKQHRELCA LHALNNVFQD GAAFSRDALQ DIYQRLSPST LVTPHKKNML GNGNYDVNVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCATGCTCAC GTTGAGCCAG AGAGCTGCAA GGAAAAAGTA CAAGAGACAA AGGAATAAAC 60
AACTCAAGGA GTGGACGCGA AAACACTAAC TCAGAGGAAC GAACACAGTA AAGACAGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR006155--Josephin

PROSITE

PS50957--JOSEPHIN

Pfam

PF02099--Josephin

SMART

SM01246--Josephin

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination

KEGG

dre:767655

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002429	Ailuropoda melanoleuca	67.89	2.00e-79	288.00
IUUC-Apl-003240	Anas platyrhynchos	78.41	2.00e-76	278.00
IUUC-Aca-004262	Anolis carolinensis	70.51	9.00e-81	292.00
IUUC-Ame-011040	Astyanax mexicanus	90.68	6.00e-119	419.00
IUUC-Bta-012440	Bos taurus	69.44	1.00e-80	291.00
IUUC-Cja-019461	Callithrix jacchus	69.44	2.00e-80	291.00
IUUC-Cfa-021002	Canis familiaris	68.52	2.00e-79	287.00
IUUC-Cpo-021309	Cavia porcellus	69.44	3.00e-80	290.00
IUUC-Csa-023194	Chlorocebus sabaeus	69.44	1.00e-80	291.00
IUUC-Cho-025019	Choloepus hoffmanni	69.91	3.00e-80	291.00
IUUC-Csv-026011	Ciona savignyi	58.25	7.00e-58	216.00
IUUC-Dno-029803	Dasypus novemcinctus	69.91	6.00e-80	290.00
IUUC-Dor-030619	Dipodomys ordii	78.42	4.00e-57	214.00
IUUC-Ete-032777	Echinops telfairi	69.31	3.00e-80	290.00
IUUC-Eca-034395	Equus caballus	69.44	1.00e-80	292.00
IUUC-Eeu-035075	Erinaceus europaeus	51.39	9.00e-50	189.00
IUUC-Fca-035819	Felis catus	68.52	6.00e-80	290.00
IUUC-Fal-037330	Ficedula albicollis	67.58	2.00e-77	281.00
IUUC-Gmo-038979	Gadus morhua	79.26	6.00e-89	319.00
IUUC-Gga-040456	Gallus gallus	78.41	3.00e-76	277.00
IUUC-Gac-041797	Gasterosteus aculeatus	80.56	3.00e-92	330.00
IUUC-Ggo-045586	Gorilla gorilla	69.27	6.00e-81	293.00
IUUC-Hsa-047008	Homo sapiens	69.91	7.00e-81	293.00
IUUC-Itr-048432	Ictidomys tridecemlineatus	69.91	8.00e-81	292.00
IUUC-Lch-049682	Latimeria chalumnae	64.81	4.00e-73	267.00
IUUC-Loc-051775	Lepisosteus oculatus	75.21	1.00e-86	312.00
IUUC-Laf-054283	Loxodonta africana	67.89	2.00e-77	281.00
IUUC-Mcc-055073	Macaca mulatta	70.05	8.00e-83	299.00
IUUC-Meu-056650	Macropus eugenii	68.52	7.00e-80	289.00
IUUC-Mga-059703	Meleagris gallopavo	78.41	3.00e-76	277.00
IUUC-Mdo-062114	Monodelphis domestica	68.98	1.00e-79	288.00
IUUC-Mmu-064230	Mus musculus	68.98	6.00e-80	290.00
IUUC-Mpu-065845	Mustela putorius furo	68.06	6.00e-79	286.00
IUUC-Mlu-067564	Myotis lucifugus	78.41	9.00e-77	279.00
IUUC-Nle-069516	Nomascus leucogenys	69.44	2.00e-80	291.00
IUUC-Opr-070945	Ochotona princeps	59.72	3.00e-63	234.00
IUUC-Ont-071439	Oreochromis niloticus	78.57	2.00e-92	332.00
IUUC-Oan-073122	Ornithorhynchus anatinus	76.76	1.00e-56	211.00
IUUC-Ocu-074128	Oryctolagus cuniculus	74.36	3.00e-47	179.00
IUUC-Ola-086972	Oryzias latipes	72.94	1.00e-79	288.00
IUUC-Oga-088786	Otolemur garnettii	68.98	3.00e-86	310.00
IUUC-Oar-089212	Ovis aries	69.12	3.00e-79	287.00
IUUC-Ptr-090936	Pan troglodytes	69.91	7.00e-81	293.00
IUUC-Pan-092234	Papio anubis	69.91	7.00e-81	293.00
IUUC-Psi-093448	Pelodiscus sinensis	68.06	2.00e-78	285.00
IUUC-Pfo-096711	Poecilia formosa	72.97	1.00e-92	332.00
IUUC-Pab-097628	Pongo abelii	69.91	7.00e-81	293.00
IUUC-Pca-100555	Procavia capensis	75.16	2.00e-64	237.00
IUUC-Ppe-102087	Prunus persica	37.43	7.00e-28	116.00
IUUC-Pva-102259	Pteropus vampyrus	68.98	3.00e-80	291.00
IUUC-Rno-105045	Rattus norvegicus	69.44	2.00e-80	291.00
IUUC-Sha-107606	Sarcophilus harrisii	68.98	4.00e-80	290.00
IUUC-Sly-111452	Solanum lycopersicum	38.20	2.00e-27	115.00
IUUC-Stu-112215	Solanum tuberosum	37.57	3.00e-26	111.00
IUUC-Ssc-115663	Sus scrofa	69.44	1.00e-80	292.00
IUUC-Tgu-117374	Taeniopygia guttata	69.91	4.00e-80	290.00
IUUC-Tru-118030	Takifugu rubripes	75.93	5.00e-91	327.00
IUUC-Tsy-119298	Tarsius syrichta	68.98	2.00e-79	287.00
IUUC-Tni-119797	Tetraodon nigroviridis	76.39	1.00e-83	302.00
IUUC-Tbe-127896	Tupaia belangeri	69.91	5.00e-81	293.00
IUUC-Ttr-128523	Tursiops truncatus	69.44	6.00e-80	290.00
IUUC-Vpa-130184	Vicugna pacos	66.67	1.00e-81	295.00
IUUC-Vvi-131246	Vitis vinifera	39.11	1.00e-26	112.00
IUUC-Xtr-131903	Xenopus tropicalis	68.06	6.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence