iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Smo-108703

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

GL377572

Gene Name

SELMODRAFT_86216

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SELMODRAFT_86216	EFJ32327	EFJ32327

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-47	162.7	305	763
UBD/Alpha-Helix/UBA	9.00e-15	55.0	594	634

Active Site

Position(s)	Description	Evidence
314	Nucleophile	{ECO:0000256\|PIRSR:PIRSR016308-1}
741	Proton acceptor	{ECO:0000256\|PIRSR:PIRSR016308-1}

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.......kskkkavsprellkalkkeaeefsgyeqqDaq 93
           tGl NlgN+CY+ SvLQ ++++++++  +    k  +  + +  +p+++l ++l kl + l+        + +k + pr++++ +++ ++ef +++qqDa 
   Q: 305  TGLVNLGNSCYLASVLQIIFATRDFQLRYYGnLKLDDAFQLAAADPTQDLNTQLSKLGHGLLsgkyseqPEFQKGIPPRMFKSLIGAGHPEFASSRQQDAF 405
           7************************9776665555566666779*****************86654444455569************************** PP
   S: 94   EflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke......... 185
           Ef++++l+q+e+e                             +  ++  s+ F++ ++++i+c + ++v+ ++   + lsl +p +  t+           
   Q: 406  EFFQYFLEQVEREN--------------------------VAN-PNEDPSRCFKFLVEERIVCCSSGKVKYTKRVDNALSLTLPLDAATNRDevaayekit 479
           ***********998..........................223.3344689*******************9988888888888888877666889****** PP
   S: 186  .................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.. 267
                             l+ cL+ f++++e+e    +y++  +++++a k+++l ++P +L lh+ +f+ + + ++++k++  +++p+++d+s++  +  
   Q: 480  seggnsgekievvrpriPLSACLDRFAAPDEVE----FYSTAVNARTTALKMTSLATFPTYLLLHMRKFQLDAS-WVPKKLDVFLDVPDTIDISHMRGKgl 575
           ********************************9....9*******************************99887.*******************9999999 PP
   S: 268  ..............................................................................peekqke................ 274
                                                                                         +     e                
   Q: 576  qpgeellpeaddeaegpvadeaivsqlmdmgfprvrcekaaiftsnhgaepamewllshmddpdidvpyshsssnanvD-----Enavqalvalgfsadla 671
           9999999888888888888888888888888887777777777777777777777777777777777766665555550.....05555566666666666 PP
   S: 275  .................................................kkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtev 317
                                                            + kY+L++ v+H+G s+ +GHYva++ + +g+W+ f+D kV  +
   Q: 672  rkalratggrtedaaewifsnsddanameldvggsstpsssvphdlpdgSGKYKLMGFVSHMGsSTLCGHYVAHILK-EGRWVIFNDAKVALS 763
           6666666666666666666666777777788888888888888899999****************************.9**********9765 PP

UBD/Alpha-Helix/UBA

   S: 2    ededkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           +de ++ ql++MGF+r ++ +a   + n  +e A+e+Ll++
   Q: 594  ADEAIVSQLMDMGFPRVRCEKAAIFTsNHGAEPAMEWLLSH 634
           58999**********************************97 PP

Organism

Selaginella moellendorffii

Protein Sequence
(Fasta)

MALSNVGMPQ ASTRIYKEEC CLTFDTPKSD GGLFVDLTSF LAFGREQAMW NFKKTGSSVY 60
LHIKHTLKES DEEDDRPHKK PTLLAIGVEG GFETKEPEYD ETLSIVILPD YQTLPLSSAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTCT CCAACGTTGG GATGCCGCAG GCCTCGACGC GGATCTACAA GGAGGAGTGC 60
TGCCTCACGT TCGACACGCC GGTAAGAATC ATCCTCGTAG CCTGGATTAT GAGCTCTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR016652--Ubiquitinyl_hydrolase
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00627--UBA
PF00443--UCH
PF02148--zf-UBP

SMART

SM00165--UBA
SM00290--ZnF_UBP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

smo:SELMODRAFT_86216

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007890	Ashbya gossypii	29.09	4.00e-76	278.00
IUUC-Acl-008057	Aspergillus clavatus	36.28	4.00e-124	437.00
IUUC-Afl-008547	Aspergillus flavus	37.32	1.00e-117	416.00
IUUC-Afu-008805	Aspergillus fumigatus	35.51	9.00e-117	413.00
IUUC-Ani-009441	Aspergillus nidulans	35.38	6.00e-102	364.00
IUUC-Aor-010111	Aspergillus oryzae	36.30	1.00e-128	452.00
IUUC-Bgr-012183	Blumeria graminis	34.11	1.00e-116	413.00
IUUC-Bci-013858	Botrytis cinerea	37.30	4.00e-128	451.00
IUUC-Bdi-014904	Brachypodium distachyon	59.32	0.00e+00	923.00
IUUC-Cel-018625	Caenorhabditis elegans	35.07	2.00e-124	439.00
IUUC-Cin-025411	Ciona intestinalis	43.59	0.00e+00	645.00
IUUC-Cgl-026667	Colletotrichum gloeosporioides	34.79	2.00e-108	385.00
IUUC-Cne-026831	Cryptococcus neoformans	36.82	1.00e-122	433.00
IUUC-Cme-027335	Cyanidioschyzon merolae	30.11	2.00e-41	164.00
IUUC-Fso-038158	Fusarium solani	36.42	8.00e-125	440.00
IUUC-Ggr-040098	Gaeumannomyces graminis	35.48	3.00e-118	418.00
IUUC-Hvu-047563	Hordeum vulgare	60.22	0.00e+00	746.00
IUUC-Lma-053216	Leptosphaeria maculans	37.47	2.00e-118	421.00
IUUC-Mpo-057589	Magnaporthe poae	35.80	5.00e-121	427.00
IUUC-Mla-058903	Melampsora laricipopulina	33.62	2.00e-116	412.00
IUUC-Mac-065634	Musa acuminata	66.75	9.00e-167	580.00
IUUC-Nfi-068558	Neosartorya fischeri	37.18	4.00e-127	447.00
IUUC-Ncr-068960	Neurospora crassa	34.72	7.00e-112	397.00
IUUC-Pgr-103343	Puccinia graminis	34.47	3.00e-106	378.00
IUUC-Ptt-103928	Puccinia triticina	30.21	1.00e-100	359.00
IUUC-Pyt-104696	Pyrenophora triticirepentis	36.39	6.00e-113	400.00
IUUC-Spo-108144	Schizosaccharomyces pombe	32.89	9.00e-112	397.00
IUUC-Sre-115225	Sporisorium reilianum	35.25	1.00e-119	423.00
IUUC-Tsy-119278	Tarsius syrichta	39.63	2.00e-164	572.00
IUUC-Tre-122043	Trichoderma reesei	37.67	4.00e-126	444.00
IUUC-Tur-126732	Triticum urartu	56.65	0.00e+00	895.00
IUUC-Uma-129599	Ustilago maydis	35.60	3.00e-124	438.00
IUUC-Vda-129688	Verticillium dahliae	36.03	4.00e-118	418.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence