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Tag Content
iUUCD ID IUUC-Bra-016775
Ensembl Protein ID Bra026301.1-P
UniProt Accession M4EBZ2; M4EBZ2_BRARP
Protein Name E3 ubiquitin-protein ligase
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
Bra026301 Bra026301.1 Bra026301.1-P
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 34.56 6.00e-36 148.00 IUUC-Dme-031700
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Brassica rapa
Functional Description
(View)

Functional Description



     E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
Protein Sequence
(Fasta)
MDMDSMESST RSVQNDEIHH NGTFHFSSTK SHGGGGAASP AVVTNIVGPT ATSVYELLEC 60
PVCTCSMYPP IHQCHNGHTL CSTCKVRVHN RCPTCRQELG DIRCLALEKV AESLELPCKF 120
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Protein Fasta Sequence



>IUUC-Bra-016775|E3,RING|Brassica rapa
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Nucleotide Sequence
(Fasta)
ATGGATATGG ATAGTATGGA ATCGTCGACG AGAAGCGTTC AGAACGATGA GATCCATCAC 60
AACGGAACTT TCCACTTCTC TTCCACCAAG AGCCACGGCG GCGGAGGCGC CGCTTCTCCC 120
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Nucleotide Fasta Sequence



>IUUC-Bra-016775|E3,RING|Brassica rapa
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Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Bol-015884 Brassica oleracea 99.07 0.00e+00 670.00
IUUC-Cel-018320 Caenorhabditis elegans 33.45 2.00e-37 149.00
IUUC-Dme-031700 Drosophila melanogaster 35.48 3.00e-33 135.00
IUUC-Opr-070341 Ochotona princeps 26.58 2.00e-12 65.90
IUUC-Oan-073701 Ornithorhynchus anatinus 25.15 7.00e-12 63.90
IUUC-Tsy-119548 Tarsius syrichta 31.96 2.00e-08 52.40
Created Date 25-Jun-2017

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