iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Stu-112474

Ensembl Protein ID

PGSC0003DMT400054414

UniProt Accession

M1BWA5; M1BWA5_SOLTU

Protein Name

E3 ubiquitin-protein ligase

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PGSC0003DMG400021123	PGSC0003DMT400054414	PGSC0003DMT400054414

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	33.98	2.00e-39	159.00	IUUC-Dme-031700

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Solanum tuberosum

Functional Description
(View)

E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

Protein Sequence
(Fasta)

MTAVSPYFDD LRCQPEVIHP PQNEDCTVIG EHMNEPAQHT AKPNVTVSSS VRELLECPVC 60
LNAMYPPIHQ CSNGHTLCSG CKPRVHNRCP TCRHELGNIR CLALEKVAAS LELPCKYQSF 120

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Nucleotide Sequence
(Fasta)

ATCTCTCTTC TTCTCCACCA AATCCAAACC CCCCATTTGG CGCCTACTGC CTATTTACTA 60
AACCCTGTTT GTCTTAAGTT CACATTCAAC TTGCAAACAC GGGCGGGCCC CTAAATTTTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018121--7-in-absentia-prot_TRAF-dom
IPR004162--SINA-like
IPR008974--TRAF-like
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR013010--Znf_SIAH

PROSITE

PS50089--ZF_RING_2
PS51081--ZF_SIAH

Pfam

PF03145--Sina

Gene Ontology

GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007275--P:multicellular organism development
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

sot:102599941

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-003118	Amborella trichopoda	82.95	2.00e-155	540.00
IUUC-Ame-011196	Astyanax mexicanus	32.68	2.00e-43	168.00
IUUC-Cin-025674	Ciona intestinalis	34.94	9.00e-42	162.00
IUUC-Csv-026233	Ciona savignyi	35.34	6.00e-42	162.00
IUUC-Dme-031700	Drosophila melanogaster	34.54	1.00e-36	145.00
IUUC-Ete-032423	Echinops telfairi	35.71	3.00e-41	160.00
IUUC-Eeu-035314	Erinaceus europaeus	35.71	4.00e-41	160.00
IUUC-Gmo-039091	Gadus morhua	34.78	3.00e-37	147.00
IUUC-Gma-042926	Glycine max	86.89	7.00e-163	565.00
IUUC-Loc-052191	Lepisosteus oculatus	33.22	4.00e-42	164.00
IUUC-Mtr-058422	Medicago truncatula	85.57	7.00e-160	555.00
IUUC-Opr-070341	Ochotona princeps	26.51	3.00e-12	64.30
IUUC-Oan-073701	Ornithorhynchus anatinus	24.83	6.00e-12	63.50
IUUC-Oba-075789	Oryza barthii	83.28	5.00e-155	538.00
IUUC-Obr-076037	Oryza brachyantha	83.83	8.00e-156	541.00
IUUC-Ogl-077148	Oryza glaberrima	83.28	5.00e-155	538.00
IUUC-Ogu-078042	Oryza glumaepatula	83.28	3.00e-155	539.00
IUUC-Oin-079325	Oryza indica	83.61	2.00e-155	540.00
IUUC-Olo-080244	Oryza longistaminata	83.28	1.00e-155	541.00
IUUC-Oni-082163	Oryza nivara	83.28	5.00e-155	538.00
IUUC-Oru-084833	Oryza rufipogon	83.61	2.00e-155	540.00
IUUC-Osa-085316	Oryza sativa	83.61	2.00e-155	540.00
IUUC-Pma-094387	Petromyzon marinus	34.93	2.00e-43	167.00
IUUC-Ppa-095212	Physcomitrella patens	85.98	7.00e-139	485.00
IUUC-Pva-103132	Pteropus vampyrus	23.93	7.00e-11	59.70
IUUC-Sit-110245	Setaria italica	84.26	1.00e-154	537.00
IUUC-Sbi-114035	Sorghum bicolor	83.93	8.00e-155	538.00
IUUC-Tru-118250	Takifugu rubripes	34.19	2.00e-41	161.00
IUUC-Tsy-119548	Tarsius syrichta	29.06	1.00e-08	52.00
IUUC-Tni-120488	Tetraodon nigroviridis	36.21	1.00e-39	155.00
IUUC-Tca-121228	Theobroma cacao	89.51	5.00e-167	578.00
IUUC-Tur-126259	Triticum urartu	82.68	1.00e-150	523.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence