iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dno-028938

Ensembl Protein ID

ENSDNOP00000010916.3

UniProt Accession

C1FXS6; C1FXS6_DASNO

Genbank Protein ID

ACO06221.1

Protein Name

Bromodomain and WD repeat domain containing 1 isoform A (Predicted)

Genbank Nucleotide ID

DP001079

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDNOG00000014021.3	ENSDNOT00000014056.3	ENSDNOP00000010916.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-36	121.6	186	223
UBD/Beta-Prp	3.60e-55	187.6	289	545

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 186  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 223
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl......lrslsgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlsls 101
           ++++++++dgt+  w+++ ++l      l+  ++  ++v+ ++  fs  g +l+tgs+D++i+ +   ++t++ +  l+ h+d+v s++
   Q: 289  RYMVSTGADGTVCFWQWDLESLkfsprpLKFTEKPRPGVQMLCssFSVGGMFLATGSTDHVIRMYflGFETPEKIAELESHTDKVDSIQ 377
           799****************99999988777778888888755522888888**************99999******************* PP
   S: 102  fspsgdklvsGshdrtirvwdletgqclee...............tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
           f+ +gd+++sGs+d t+r+w  e+ ++ +                 ++  +  v++++++++++++v++ +D ++++W++ tg+ll+ l
   Q: 378  FCNNGDRFLSGSRDGTARIWRFEQLEWRSIlldmatrmsgemnseEERFMKPKVTMIAWNKNDSIVVTAVNDHVLKVWNSYTGQLLHNL 466
           ************************999988999********8777666667789*********************************** PP
   S: 176  tgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
            g h d v  l+   fds  + ++s+++dg++ +wd+ +g  ++ + +         v + +fsp++++++++ s+g + i+
   Q: 467  LG-HADEVFVLEthpFDS--RIMLSAGHDGSIFIWDITKGAKMKHYFNMIegqghGAVFDCKFSPDGQHFACTDSHGHLLIF 545
           *9.*********555555..99****************99996666654434445667778999********9999998886 PP

Organism

Dasypus novemcinctus

Protein Sequence
(Fasta)

VARPSPTEPR NCLVESSYQF ILLWIVHLGL CIRNVCLTQA HCMGQLVFTR RPWELNSGTS 60
HMNLFSTQVL SNKHVAPDHL LQICQRIGPM LDKEIPPSIS RVTSLLGAGR QSLLRTAKDC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTTGCAAGGC CCTCCCCCAC AGAGCCAAGA AATTGACTNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNCC TGTCGTTTGT GTGTCTGTTC CTATTCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	83.57	0.00e+00	3252.00
IUUC-Apl-004083	Anas platyrhynchos	67.32	0.00e+00	1896.00
IUUC-Ame-010718	Astyanax mexicanus	66.97	0.00e+00	1094.00
IUUC-Bta-013217	Bos taurus	84.25	0.00e+00	3531.00
IUUC-Cja-019966	Callithrix jacchus	84.87	0.00e+00	3494.00
IUUC-Cfa-021037	Canis familiaris	84.47	0.00e+00	3480.00
IUUC-Cpo-021934	Cavia porcellus	87.78	0.00e+00	2624.00
IUUC-Csa-023352	Chlorocebus sabaeus	86.06	0.00e+00	3338.00
IUUC-Cho-024690	Choloepus hoffmanni	86.37	0.00e+00	1553.00
IUUC-Dre-028205	Danio rerio	65.37	0.00e+00	1071.00
IUUC-Ete-032717	Echinops telfairi	69.29	0.00e+00	823.00
IUUC-Eca-034349	Equus caballus	88.31	0.00e+00	3484.00
IUUC-Fca-035485	Felis catus	79.92	0.00e+00	3015.00
IUUC-Ggo-045500	Gorilla gorilla	84.95	0.00e+00	3514.00
IUUC-Hsa-046350	Homo sapiens	85.01	0.00e+00	3536.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	93.76	0.00e+00	1117.00
IUUC-Lch-049662	Latimeria chalumnae	55.45	0.00e+00	1997.00
IUUC-Laf-053848	Loxodonta africana	84.69	0.00e+00	3493.00
IUUC-Mcc-054638	Macaca mulatta	84.55	0.00e+00	3504.00
IUUC-Meu-056739	Macropus eugenii	79.33	0.00e+00	1112.00
IUUC-Mmr-061227	Microcebus murinus	86.21	0.00e+00	3572.00
IUUC-Mdo-062074	Monodelphis domestica	80.72	0.00e+00	2388.00
IUUC-Mmu-064075	Mus musculus	78.42	0.00e+00	2818.00
IUUC-Mpu-066643	Mustela putorius furo	88.36	0.00e+00	2928.00
IUUC-Mlu-067735	Myotis lucifugus	84.87	0.00e+00	3432.00
IUUC-Nle-069402	Nomascus leucogenys	88.05	0.00e+00	2840.00
IUUC-Oan-072954	Ornithorhynchus anatinus	68.08	0.00e+00	2711.00
IUUC-Ocu-074456	Oryctolagus cuniculus	84.66	0.00e+00	3526.00
IUUC-Ogu-078641	Oryza glumaepatula	39.67	2.00e-30	128.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.25	1.00e-56	215.00
IUUC-Oga-087938	Otolemur garnettii	77.84	0.00e+00	3004.00
IUUC-Oar-090214	Ovis aries	85.66	0.00e+00	3476.00
IUUC-Ptr-091213	Pan troglodytes	84.97	0.00e+00	3487.00
IUUC-Pan-092444	Papio anubis	84.00	0.00e+00	3480.00
IUUC-Pfo-097318	Poecilia formosa	61.19	0.00e+00	1692.00
IUUC-Pab-097573	Pongo abelii	85.16	0.00e+00	3425.00
IUUC-Pca-100759	Procavia capensis	71.71	0.00e+00	1084.00
IUUC-Pva-102782	Pteropus vampyrus	86.13	0.00e+00	3518.00
IUUC-Rno-105687	Rattus norvegicus	74.74	0.00e+00	3101.00
IUUC-Sha-106680	Sarcophilus harrisii	63.64	0.00e+00	1419.00
IUUC-Sar-113519	Sorex araneus	80.27	0.00e+00	1759.00
IUUC-Tsy-118921	Tarsius syrichta	87.31	0.00e+00	1920.00
IUUC-Tbe-127663	Tupaia belangeri	76.43	0.00e+00	1282.00
IUUC-Ttr-128561	Tursiops truncatus	83.05	0.00e+00	3300.00
IUUC-Vpa-130444	Vicugna pacos	83.37	0.00e+00	3258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence