iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-062074

Ensembl Protein ID

ENSMODP00000026232.4

UniProt Accession

F6S5Z5; F6S5Z5_MONDO

Protein Name

Uncharacterized protein

Gene Name

BRWD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020973.4	ENSMODT00000026699.4	ENSMODP00000026232.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-37	125.9	184	221
UBD/Beta-Prp	8.60e-55	186.2	328	543

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + v+c+af  + +++ +GsdD+ +k+W+++ g+ll
   Q: 184  GHLSAVYCVAFdRTgHRIFTGSDDCLVKIWSTHNGRLL 221
           8**********955599***************999987 PP

UBD/Beta-Prp

   S: 56   tavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee........... 131
            + +fs  g +l+tgs+D++i+ +   ++ ++ +  l+ h+d+v s++fs +gd+++sGs+d t+r+w+ e+ ++ +            
   Q: 328  LCSSFSVGGMFLATGSTDHVIRMYflGFEMPEKIAELESHTDKVDSIQFSNNGDRFLSGSRDGTARIWKFEQPEWKSIlldmatrlsrd 416
           4667888899**************99999**********************************************9999********** PP
   S: 132  ....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlq... 210
                ++  +  v++++++ ++ l+v++ +D ++++Wd+ tg+ll+ l g htd v  l+   fds  + ++s+++dg + +wd+    
   Q: 417  lcseEEKFMKPKVTMIAWNRNDTLVVTAVNDHVLKVWDSHTGQLLHNLVG-HTDEVFVLEthpFDS--RIMLSAGHDGNIFIWDITkgi 502
           9887666777789***********************************99.*********555555..99***************9666 PP
   S: 211  .tgecvrtlnght.dnvksvrfspnderlvsgssDgsiriW 249
            t++  +  +g+    v + +fs+++++++++ s+g + i+
   Q: 503  kTKHYFNMIEGQGhGAVFDCKFSSDGQHFACTDSHGHLLIF 543
           65555555555333566678899999999999999988876 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MAEHSASRHP VPPIESELYF LIARYLSAGP CRRAAQVLVQ ELEQYQLLPK RLDWEGNEYD 60
WKYEDLVLSN KHVAPDHLLQ ICQRIGPILD KEIPPCISRV TSLLGAGRQS LLRTAKDCRD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAACTTTAA AGAGCTGTCA TTGACTTTGA GCCTTGACAA TGAACTAAGC GGATTGTCCA 60
GGCAGCAAGA CGGTTTTCTC GGTCTTTTAT ATTCAGGCAA CAACCAAAGT CGCACAGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

KEGG

mdo:100017599

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002332	Ailuropoda melanoleuca	75.01	0.00e+00	2572.00
IUUC-Aca-004348	Anolis carolinensis	71.82	0.00e+00	1925.00
IUUC-Aly-006517	Arabidopsis lyrata	30.62	5.00e-73	270.00
IUUC-Ame-010718	Astyanax mexicanus	69.43	0.00e+00	1158.00
IUUC-Bta-013217	Bos taurus	70.51	0.00e+00	2771.00
IUUC-Bdi-014797	Brachypodium distachyon	29.73	4.00e-59	224.00
IUUC-Bol-015737	Brassica oleracea	29.51	2.00e-72	268.00
IUUC-Bra-017961	Brassica rapa	29.47	9.00e-72	266.00
IUUC-Cja-019966	Callithrix jacchus	82.08	0.00e+00	2434.00
IUUC-Cfa-021037	Canis familiaris	69.52	0.00e+00	2714.00
IUUC-Cpo-021934	Cavia porcellus	81.96	0.00e+00	2456.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.80	3.00e-34	140.00
IUUC-Csa-023352	Chlorocebus sabaeus	81.57	0.00e+00	2242.00
IUUC-Cho-024690	Choloepus hoffmanni	90.88	0.00e+00	712.00
IUUC-Dre-028205	Danio rerio	68.97	0.00e+00	1140.00
IUUC-Dno-028938	Dasypus novemcinctus	68.19	0.00e+00	2696.00
IUUC-Dme-031752	Drosophila melanogaster	50.00	0.00e+00	671.00
IUUC-Eca-034349	Equus caballus	76.87	0.00e+00	2508.00
IUUC-Fca-035485	Felis catus	90.06	0.00e+00	1370.00
IUUC-Fal-037307	Ficedula albicollis	69.13	0.00e+00	2391.00
IUUC-Gga-040865	Gallus gallus	82.52	0.00e+00	1388.00
IUUC-Gma-043340	Glycine max	30.99	5.00e-72	266.00
IUUC-Ggo-045500	Gorilla gorilla	82.36	0.00e+00	2456.00
IUUC-Hsa-046350	Homo sapiens	69.98	0.00e+00	2732.00
IUUC-Itr-047962	Ictidomys tridecemlineatus	86.25	0.00e+00	1028.00
IUUC-Lch-049662	Latimeria chalumnae	77.88	0.00e+00	1314.00
IUUC-Loc-052853	Lepisosteus oculatus	72.69	0.00e+00	1178.00
IUUC-Laf-053848	Loxodonta africana	69.80	0.00e+00	2753.00
IUUC-Mcc-054638	Macaca mulatta	82.33	0.00e+00	2471.00
IUUC-Meu-056739	Macropus eugenii	86.17	0.00e+00	1201.00
IUUC-Mtr-058094	Medicago truncatula	30.91	1.00e-73	272.00
IUUC-Mmr-061227	Microcebus murinus	69.31	0.00e+00	2760.00
IUUC-Mpu-066643	Mustela putorius furo	82.96	0.00e+00	2338.00
IUUC-Mlu-067735	Myotis lucifugus	68.71	0.00e+00	2613.00
IUUC-Nle-069402	Nomascus leucogenys	82.49	0.00e+00	2447.00
IUUC-Oan-072954	Ornithorhynchus anatinus	69.89	0.00e+00	2716.00
IUUC-Ocu-074456	Oryctolagus cuniculus	83.30	0.00e+00	2431.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.71	5.00e-57	216.00
IUUC-Oga-087938	Otolemur garnettii	63.67	0.00e+00	2415.00
IUUC-Oar-090214	Ovis aries	69.54	0.00e+00	2647.00
IUUC-Ptr-091213	Pan troglodytes	82.53	0.00e+00	2454.00
IUUC-Pan-092444	Papio anubis	82.21	0.00e+00	2467.00
IUUC-Psi-093271	Pelodiscus sinensis	62.48	0.00e+00	2221.00
IUUC-Pma-094427	Petromyzon marinus	65.74	2.00e-130	457.00
IUUC-Ppa-095793	Physcomitrella patens	28.94	4.00e-73	271.00
IUUC-Pfo-097318	Poecilia formosa	62.01	0.00e+00	1746.00
IUUC-Pab-097573	Pongo abelii	81.40	0.00e+00	2375.00
IUUC-Pop-099672	Populus trichocarpa	30.46	3.00e-72	267.00
IUUC-Pva-102782	Pteropus vampyrus	69.08	0.00e+00	2652.00
IUUC-Rno-105687	Rattus norvegicus	66.56	0.00e+00	2640.00
IUUC-Sha-106680	Sarcophilus harrisii	85.04	0.00e+00	3449.00
IUUC-Sly-111348	Solanum lycopersicum	31.19	2.00e-75	278.00
IUUC-Sar-113519	Sorex araneus	71.60	0.00e+00	1575.00
IUUC-Tgu-116513	Taeniopygia guttata	76.61	0.00e+00	2263.00
IUUC-Tsy-118921	Tarsius syrichta	79.51	0.00e+00	1800.00
IUUC-Tca-121615	Theobroma cacao	29.77	5.00e-68	253.00
IUUC-Ttr-128561	Tursiops truncatus	67.97	0.00e+00	2572.00
IUUC-Vpa-130444	Vicugna pacos	67.22	0.00e+00	2424.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence