iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000053517.6	ENSDART00000156885.1	ENSDARP00000127915.1
ENSDARG00000053517.6	ENSDART00000112088.3	ENSDARP00000100360.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-53	177.5	105	143
UBD/Beta-Prp	1.10e-130	436.0	726	937

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht ++ claf  d   lvs + D  +ti vWD+r+g++l
   Q: 105  HTHGIACLAFdLDgQCLVSVGLDskNTICVWDWRQGKVL 143
           99********9665889****9999***********976 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +w+++  k l+ l+g h+ +v a++fs dgk l++++ D  +ti +w+ ++g+ ++t++g
   Q: 726  HDDDILCLAIHPVKDYVATGqvGRDSSIHIWETEFLKPLSVLKGfHQFGVCALDFSADGKRLASVGLDdnHTIVLWEWRKGEKLSTIRG 814
           4555566************96669******************6659999*******************999****************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
            +d++  ++++p+  dkl+s++ ++  + w+   g  + +    g++++ +c+v+  ++ +++sG+  + + +W  + ++l++t +  h
   Q: 815  SKDKIFVIKINPYMpDKLISAG-VKHMKFWHRAGGGLIGKkGSMGKTETMMCAVYGWTEEMVFSGTCTGDICIW--RDMFLVKTVKA-H 899
           ************9889999999.99*****98888887767999******************************..88*******98.* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           +++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 900  DGPVFSMHALE--KGFVTGGKDGIVALWDDTFERCLKTYA 937
           *******9888..67*********************9996 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MADRTAPNCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYNTR EHKQKFYLGH 60
NDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTVSI LRDMHTHGIA CLAFDLDGQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCGCCTTTC GCAATTGGCG GGTCTCAGTT AACTAATGCG AGAAATCCAT GTTCTCAGGT 60
TTTGACATGT CACTAGAGCA AAACCAGCCG TCCGGTCAGA AGTAGAGAGG AGCTTCATTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR003143--Cyt_cd1_C
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	85.16	0.00e+00	3467.00
IUUC-Apl-003360	Anas platyrhynchos	86.91	0.00e+00	3447.00
IUUC-Aca-004572	Anolis carolinensis	72.20	0.00e+00	2991.00
IUUC-Ame-011681	Astyanax mexicanus	94.92	0.00e+00	3835.00
IUUC-Bta-012838	Bos taurus	84.39	0.00e+00	3483.00
IUUC-Cja-019068	Callithrix jacchus	84.57	0.00e+00	3487.00
IUUC-Cfa-020531	Canis familiaris	85.40	0.00e+00	3529.00
IUUC-Cpo-022304	Cavia porcellus	82.43	0.00e+00	3291.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	32.07	2.00e-98	355.00
IUUC-Csa-023621	Chlorocebus sabaeus	84.16	0.00e+00	3178.00
IUUC-Cho-025038	Choloepus hoffmanni	72.85	0.00e+00	1152.00
IUUC-Cin-025205	Ciona intestinalis	58.10	0.00e+00	2424.00
IUUC-Csv-026014	Ciona savignyi	58.23	0.00e+00	2417.00
IUUC-Dno-030063	Dasypus novemcinctus	83.91	0.00e+00	3457.00
IUUC-Dor-030980	Dipodomys ordii	77.50	0.00e+00	1462.00
IUUC-Ete-032554	Echinops telfairi	83.72	0.00e+00	969.00
IUUC-Eca-033909	Equus caballus	84.69	0.00e+00	3222.00
IUUC-Eeu-035180	Erinaceus europaeus	69.40	0.00e+00	1310.00
IUUC-Fca-036307	Felis catus	74.44	0.00e+00	3051.00
IUUC-Fal-037219	Ficedula albicollis	87.30	0.00e+00	3565.00
IUUC-Gmo-039146	Gadus morhua	88.09	0.00e+00	3567.00
IUUC-Gga-041095	Gallus gallus	86.52	0.00e+00	2572.00
IUUC-Gac-041341	Gasterosteus aculeatus	91.35	0.00e+00	3668.00
IUUC-Ggo-045107	Gorilla gorilla	73.88	0.00e+00	3040.00
IUUC-Hsa-045997	Homo sapiens	84.67	0.00e+00	3494.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	72.98	0.00e+00	2957.00
IUUC-Lch-050306	Latimeria chalumnae	84.88	0.00e+00	3190.00
IUUC-Loc-052215	Lepisosteus oculatus	91.19	0.00e+00	3759.00
IUUC-Laf-054044	Loxodonta africana	83.79	0.00e+00	3469.00
IUUC-Mcc-054733	Macaca mulatta	84.67	0.00e+00	3487.00
IUUC-Meu-055977	Macropus eugenii	75.18	0.00e+00	1847.00
IUUC-Mga-059666	Meleagris gallopavo	85.87	0.00e+00	3386.00
IUUC-Mmr-060995	Microcebus murinus	85.01	0.00e+00	3482.00
IUUC-Mdo-062482	Monodelphis domestica	85.71	0.00e+00	3536.00
IUUC-Mmu-063533	Mus musculus	84.67	0.00e+00	3455.00
IUUC-Mpu-066704	Mustela putorius furo	85.23	0.00e+00	3513.00
IUUC-Mlu-067592	Myotis lucifugus	84.27	0.00e+00	3465.00
IUUC-Nle-069911	Nomascus leucogenys	84.76	0.00e+00	3484.00
IUUC-Opr-070213	Ochotona princeps	73.27	0.00e+00	1615.00
IUUC-Ont-071966	Oreochromis niloticus	93.11	0.00e+00	3787.00
IUUC-Oan-073563	Ornithorhynchus anatinus	73.86	0.00e+00	3026.00
IUUC-Ocu-074531	Oryctolagus cuniculus	74.24	0.00e+00	3051.00
IUUC-Ola-086738	Oryzias latipes	91.77	0.00e+00	3720.00
IUUC-Olu-087860	Ostreococcus lucimarinus	36.54	2.00e-114	406.00
IUUC-Oga-088436	Otolemur garnettii	83.03	0.00e+00	3430.00
IUUC-Oar-090153	Ovis aries	84.68	0.00e+00	3370.00
IUUC-Ptr-091008	Pan troglodytes	84.38	0.00e+00	3469.00
IUUC-Pan-092404	Papio anubis	84.69	0.00e+00	3478.00
IUUC-Psi-093417	Pelodiscus sinensis	85.64	0.00e+00	3414.00
IUUC-Pma-094424	Petromyzon marinus	67.03	2.00e-117	415.00
IUUC-Pfo-096073	Poecilia formosa	92.59	0.00e+00	3779.00
IUUC-Pab-097900	Pongo abelii	84.12	0.00e+00	3467.00
IUUC-Pca-100107	Procavia capensis	70.62	0.00e+00	2269.00
IUUC-Pva-102880	Pteropus vampyrus	81.65	0.00e+00	3197.00
IUUC-Rno-106084	Rattus norvegicus	84.57	0.00e+00	3502.00
IUUC-Sha-106974	Sarcophilus harrisii	85.58	0.00e+00	3520.00
IUUC-Sar-113401	Sorex araneus	75.30	0.00e+00	1652.00
IUUC-Ssc-116057	Sus scrofa	84.44	0.00e+00	3421.00
IUUC-Tgu-116807	Taeniopygia guttata	74.14	0.00e+00	3020.00
IUUC-Tru-118444	Takifugu rubripes	91.62	0.00e+00	3690.00
IUUC-Tsy-118941	Tarsius syrichta	74.24	0.00e+00	2553.00
IUUC-Tni-120683	Tetraodon nigroviridis	90.97	0.00e+00	3523.00
IUUC-Tbe-127467	Tupaia belangeri	77.83	0.00e+00	1656.00
IUUC-Ttr-129138	Tursiops truncatus	81.64	0.00e+00	3202.00
IUUC-Vpa-130083	Vicugna pacos	79.59	0.00e+00	3104.00
IUUC-Xtr-131835	Xenopus tropicalis	85.46	0.00e+00	3541.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence