iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050306

Ensembl Protein ID

ENSLACP00000010327.1

UniProt Accession

H3AL06; H3AL06_LATCH

Genbank Protein ID

ENSLACP00000010327

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01003008

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000009095.1	ENSLACT00000010405.1	ENSLACP00000010327.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-51	168.3	1527	1556
UBD/Beta-Prp	9.00e-109	363.5	554	768

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    d.svtclaf.sd.tllvsGsdDgtikvWDl 30
           d ++++la  ++ + ++s++ Dgt+++WD+
   Q: 1527 DgPIWGLAThPSrDVFLSAAEDGTVRLWDI 1556
           526999998977899**************6 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +wd++t k l+ l+g h+ +v a++fs dgk l++++ D  +ti +wd ++g+ +++ +g
   Q: 554  HDDDILCLAIHPLKDYVATGqvGRDASIHIWDTETLKPLSVLKGcHQFGVCALDFSADGKRLASVGLDdsHTIILWDWKKGEKLSASRG 642
           4555666************96569******************7736667*******************99******************* PP
   S: 93   hedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
            ++++  ++++p   +++v+++  +  + w+   g  +          ++++ +c+v+   + +++sG+  + + +W+   ++l++t +
   Q: 643  SKEKIFVVKINPfMHESIVTAG-IKHMKFWHRAGGGMIGRkgcvGPGAKMETMMCAVYGWAEEMVFSGTSTGDICIWRG--MFLVKTIK 728
           ************6667777777.9999***988777776688876777889999****9999***************66..*******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
             h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 729  A-HDGPVFSMHALE--KGFVTGGKDGVVALWDDSFERCLKTYA 768
           8.********9888..67**********************996 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

FQFWSLCGNA LTPKRGVFGK TGDLQTILCL ACARDEVTYS GALNGDIYVW KGVNLVRTVQ 60
GAHASGIFSM NACEEGFATG GRDGCVRLWD LNFKPITVID LRETDQGYKG LSVRSVCWRG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCAGTTTT GGAGCTTGTG CGGGAATGCC TTGACGCCAA AGCGTGGCGT TTTTGGTAAA 60
ACCGGTGACC TCCAGACTAT TCTGTGCCTG GCCTGTGCGA GGGATGAAGT CACGTACTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	84.81	0.00e+00	3160.00
IUUC-Apl-003360	Anas platyrhynchos	87.20	0.00e+00	3206.00
IUUC-Aca-004572	Anolis carolinensis	71.55	0.00e+00	2654.00
IUUC-Ame-011681	Astyanax mexicanus	85.08	0.00e+00	3166.00
IUUC-Bta-012838	Bos taurus	83.72	0.00e+00	3122.00
IUUC-Cja-019068	Callithrix jacchus	84.53	0.00e+00	3125.00
IUUC-Cfa-020531	Canis familiaris	85.07	0.00e+00	3185.00
IUUC-Cpo-022304	Cavia porcellus	82.22	0.00e+00	3068.00
IUUC-Csa-023621	Chlorocebus sabaeus	84.35	0.00e+00	3093.00
IUUC-Cho-024944	Choloepus hoffmanni	68.51	0.00e+00	1344.00
IUUC-Cin-025205	Ciona intestinalis	57.48	0.00e+00	2147.00
IUUC-Csv-026014	Ciona savignyi	57.94	0.00e+00	2155.00
IUUC-Dre-028772	Danio rerio	84.60	0.00e+00	3166.00
IUUC-Dno-030063	Dasypus novemcinctus	83.86	0.00e+00	3108.00
IUUC-Dor-030980	Dipodomys ordii	77.81	0.00e+00	1448.00
IUUC-Ete-032554	Echinops telfairi	84.11	0.00e+00	962.00
IUUC-Eca-033909	Equus caballus	84.53	0.00e+00	3127.00
IUUC-Eeu-035180	Erinaceus europaeus	69.15	0.00e+00	1290.00
IUUC-Fca-036307	Felis catus	73.30	0.00e+00	2714.00
IUUC-Fal-037219	Ficedula albicollis	87.05	0.00e+00	3214.00
IUUC-Gmo-039146	Gadus morhua	81.15	0.00e+00	3029.00
IUUC-Gga-041095	Gallus gallus	85.48	0.00e+00	2184.00
IUUC-Gac-041341	Gasterosteus aculeatus	84.20	0.00e+00	3114.00
IUUC-Ggo-045107	Gorilla gorilla	73.14	0.00e+00	2711.00
IUUC-Hsa-045997	Homo sapiens	84.70	0.00e+00	3131.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	72.72	0.00e+00	2727.00
IUUC-Loc-052215	Lepisosteus oculatus	85.19	0.00e+00	3214.00
IUUC-Laf-054044	Loxodonta africana	83.96	0.00e+00	3112.00
IUUC-Mcc-054733	Macaca mulatta	84.48	0.00e+00	3121.00
IUUC-Meu-055977	Macropus eugenii	75.40	0.00e+00	1568.00
IUUC-Mga-059666	Meleagris gallopavo	85.67	0.00e+00	3145.00
IUUC-Mmr-060995	Microcebus murinus	84.90	0.00e+00	3137.00
IUUC-Mdo-062482	Monodelphis domestica	85.33	0.00e+00	3175.00
IUUC-Mmu-063533	Mus musculus	84.20	0.00e+00	3091.00
IUUC-Mpu-066704	Mustela putorius furo	84.59	0.00e+00	3155.00
IUUC-Mlu-067592	Myotis lucifugus	83.77	0.00e+00	3107.00
IUUC-Nle-069911	Nomascus leucogenys	84.68	0.00e+00	3129.00
IUUC-Opr-070213	Ochotona princeps	72.34	0.00e+00	1413.00
IUUC-Ont-071966	Oreochromis niloticus	84.77	0.00e+00	3177.00
IUUC-Oan-073563	Ornithorhynchus anatinus	72.81	0.00e+00	2688.00
IUUC-Ocu-074531	Oryctolagus cuniculus	73.47	0.00e+00	2714.00
IUUC-Ola-086738	Oryzias latipes	83.68	0.00e+00	3124.00
IUUC-Oga-088436	Otolemur garnettii	83.85	0.00e+00	3100.00
IUUC-Oar-090153	Ovis aries	84.70	0.00e+00	3147.00
IUUC-Ptr-091008	Pan troglodytes	84.37	0.00e+00	3107.00
IUUC-Pan-092404	Papio anubis	84.85	0.00e+00	3129.00
IUUC-Psi-093417	Pelodiscus sinensis	86.93	0.00e+00	3201.00
IUUC-Pfo-096073	Poecilia formosa	84.35	0.00e+00	3166.00
IUUC-Pab-097900	Pongo abelii	84.09	0.00e+00	3107.00
IUUC-Pca-100107	Procavia capensis	79.76	0.00e+00	1334.00
IUUC-Pva-102880	Pteropus vampyrus	81.82	0.00e+00	2968.00
IUUC-Rno-106084	Rattus norvegicus	84.31	0.00e+00	3142.00
IUUC-Sha-106974	Sarcophilus harrisii	85.52	0.00e+00	3174.00
IUUC-Sar-113401	Sorex araneus	78.62	0.00e+00	874.00
IUUC-Ssc-116057	Sus scrofa	84.09	0.00e+00	3191.00
IUUC-Tgu-116807	Taeniopygia guttata	73.03	0.00e+00	2669.00
IUUC-Tru-118444	Takifugu rubripes	83.73	0.00e+00	3093.00
IUUC-Tsy-118941	Tarsius syrichta	73.22	0.00e+00	2312.00
IUUC-Tni-120683	Tetraodon nigroviridis	83.31	0.00e+00	3065.00
IUUC-Tbe-127467	Tupaia belangeri	77.93	0.00e+00	1644.00
IUUC-Ttr-129138	Tursiops truncatus	82.64	0.00e+00	3043.00
IUUC-Vpa-130083	Vicugna pacos	79.20	0.00e+00	2875.00
IUUC-Xtr-131835	Xenopus tropicalis	83.68	0.00e+00	3164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence