iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052215

Ensembl Protein ID

ENSLOCP00000012778.1

UniProt Accession

W5MWL9; W5MWL9_LEPOC

Genbank Protein ID

ENSLOCP00000012778

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01003764

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000010403.1	ENSLOCT00000012802.1	ENSLOCP00000012778.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-56	185.1	105	143
UBD/Beta-Prp	2.70e-125	417.7	734	945

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht ++ claf  +   lvs + D  +ti vWD+r+g++l
   Q: 105  HTHGIACLAFdLEgQCLVSVGLDskNTICVWDWRRGKVL 143
           99********8445779****9999**********9976 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +wd++  k l+ l   h+ +v  v+fs dgk l++++ D  +t+ +wd ++g+ +++++g
   Q: 734  HDDDILCLAIHPLKDYVATGqvGRDSSIHIWDTEVLKPLSVLkGYHQYGVCGVDFSADGKRLASVGLDdnHTLVLWDWRKGEKLSAVRG 822
           4555566************96669******************5559**********************999****************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgght 180
            +d++  ++++p+   ++++  ++  + w+   g  +      g++++ +c+v+  ++ +++sG+  + + +W  + + l++t +  h+
   Q: 823  SKDKIFVVKINPYMPEKLITAGVKHMKFWHKAGGGLIGRkGHVGKMETMMCAVYGWTEEMVFSGTCTGDLCIW--RDMYLIKTVKA-HD 908
           ************9955555556*******8888877764567778999*************************..88*******98.** PP
   S: 181  dsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           ++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 909  GPVFSMHALE--KGFVTGGKDGVVALWDDTFERCLKTYA 945
           ******9888..67**********************996 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGDRTAPNGH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYNTR EHKQKFYLGH 60
NDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTVSI LKDIHTHGIA CLAFDLEGQC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGACA GAACAGCTCC AAATGGTCAC CTCCGGCTGG AATGGGTCTA CGGCTACCGA 60
GGACACCAGT GCCGCAACAA CCTGTACTAC ACGGCGGCGA AGGAAATTGT CTATTTCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	85.21	0.00e+00	3486.00
IUUC-Apl-003360	Anas platyrhynchos	87.91	0.00e+00	3472.00
IUUC-Ame-011681	Astyanax mexicanus	91.59	0.00e+00	3734.00
IUUC-Bta-012838	Bos taurus	84.69	0.00e+00	3501.00
IUUC-Cja-019068	Callithrix jacchus	84.77	0.00e+00	3494.00
IUUC-Cfa-020531	Canis familiaris	84.97	0.00e+00	3529.00
IUUC-Cpo-022304	Cavia porcellus	82.18	0.00e+00	3292.00
IUUC-Csa-023621	Chlorocebus sabaeus	83.94	0.00e+00	3179.00
IUUC-Cho-024944	Choloepus hoffmanni	66.99	0.00e+00	1335.00
IUUC-Dre-028772	Danio rerio	91.19	0.00e+00	3734.00
IUUC-Dno-030063	Dasypus novemcinctus	84.45	0.00e+00	3479.00
IUUC-Dor-030980	Dipodomys ordii	77.59	0.00e+00	1464.00
IUUC-Ete-032554	Echinops telfairi	84.79	0.00e+00	974.00
IUUC-Eca-033909	Equus caballus	85.02	0.00e+00	3243.00
IUUC-Eeu-035180	Erinaceus europaeus	69.83	0.00e+00	1318.00
IUUC-Fal-037219	Ficedula albicollis	87.76	0.00e+00	3589.00
IUUC-Gmo-039146	Gadus morhua	87.04	0.00e+00	3539.00
IUUC-Gga-041095	Gallus gallus	87.37	0.00e+00	2600.00
IUUC-Gac-041341	Gasterosteus aculeatus	89.56	0.00e+00	3626.00
IUUC-Hsa-045997	Homo sapiens	85.18	0.00e+00	3509.00
IUUC-Lch-050306	Latimeria chalumnae	85.19	0.00e+00	3212.00
IUUC-Laf-054044	Loxodonta africana	83.89	0.00e+00	3477.00
IUUC-Mcc-054733	Macaca mulatta	84.97	0.00e+00	3499.00
IUUC-Meu-055977	Macropus eugenii	75.18	0.00e+00	1843.00
IUUC-Mga-059666	Meleagris gallopavo	87.00	0.00e+00	3431.00
IUUC-Mmr-060995	Microcebus murinus	85.13	0.00e+00	3494.00
IUUC-Mdo-062482	Monodelphis domestica	86.13	0.00e+00	3557.00
IUUC-Mmu-063533	Mus musculus	84.57	0.00e+00	3465.00
IUUC-Mpu-066704	Mustela putorius furo	85.33	0.00e+00	3530.00
IUUC-Mlu-067592	Myotis lucifugus	84.40	0.00e+00	3474.00
IUUC-Nle-069911	Nomascus leucogenys	84.77	0.00e+00	3489.00
IUUC-Ont-071966	Oreochromis niloticus	91.71	0.00e+00	3761.00
IUUC-Ola-086738	Oryzias latipes	90.33	0.00e+00	3687.00
IUUC-Oga-088436	Otolemur garnettii	82.68	0.00e+00	3429.00
IUUC-Oar-090153	Ovis aries	84.93	0.00e+00	3386.00
IUUC-Ptr-091008	Pan troglodytes	84.88	0.00e+00	3484.00
IUUC-Pan-092404	Papio anubis	84.57	0.00e+00	3481.00
IUUC-Psi-093417	Pelodiscus sinensis	87.38	0.00e+00	3459.00
IUUC-Ppa-095656	Physcomitrella patens	24.25	4.00e-16	81.30
IUUC-Pfo-096073	Poecilia formosa	91.24	0.00e+00	3751.00
IUUC-Pab-097900	Pongo abelii	84.52	0.00e+00	3482.00
IUUC-Pva-102880	Pteropus vampyrus	81.71	0.00e+00	3202.00
IUUC-Rno-106084	Rattus norvegicus	84.67	0.00e+00	3518.00
IUUC-Sha-106974	Sarcophilus harrisii	85.70	0.00e+00	3534.00
IUUC-Ssc-116057	Sus scrofa	85.23	0.00e+00	3464.00
IUUC-Tru-118444	Takifugu rubripes	90.03	0.00e+00	3656.00
IUUC-Tsy-118941	Tarsius syrichta	75.88	0.00e+00	2285.00
IUUC-Tni-120683	Tetraodon nigroviridis	89.65	0.00e+00	3505.00
IUUC-Tbe-127467	Tupaia belangeri	77.72	0.00e+00	1661.00
IUUC-Ttr-129138	Tursiops truncatus	81.44	0.00e+00	3212.00
IUUC-Vpa-130083	Vicugna pacos	79.52	0.00e+00	3121.00
IUUC-Xtr-131835	Xenopus tropicalis	85.86	0.00e+00	3583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence