iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066704

Ensembl Protein ID

ENSMPUP00000008136.1

UniProt Accession

M3Y9X9; M3Y9X9_MUSPF

Genbank Protein ID

ENSMPUP00000008136

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01004338

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000008196.1	ENSMPUT00000008265.1	ENSMPUP00000008136.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.60e-58	190.6	236	266
UBD/Beta-Prp	7.00e-125	416.1	726	940

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDlrt 32
           Ht+++++++  +  +++G++Dg i++WDl+ 
   Q: 236  HTAGIFSMNACEEGFATGGRDGCIRLWDLTF 266
           888888886423338*************986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsg.heaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd +i +wd++t k l+ l+g h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++ +g
   Q: 726  HDDDILCLAIHPLKDYVATGqvGRDPSIHIWDTETIKPLSVLKGcHQYGVCAVDFSADGKRLASVGIDdsHTIVLWDWKKGEKLSVTRG 814
           4555566************95569******************6648889***************99999******************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
            +d++  ++++p+  dkl++++  + ++ w+   g  +         g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t +
   Q: 815  SKDKIFVVKMNPYVpDKLITAG-IKHVKFWHRAGGGLIGRkgyvGTLGKNDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVFLVKTVK 900
           ************9978888887.9******88777777668998455677799************************..889******9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
             h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 901  A-HDGPVFSMHALE--KGFVTGGKDGVVALWDDSFERCLKTYA 940
           8.********9888..67**********************996 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MAARSAPNCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICVW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCTC GGAGCGCCCC GAACTGCCAC CTGCGGCTCG AGTGGGTGTA CGGCTACCGG 60
GGCCACCAGT GCCGCAACAA CCTCTACTAC ACGGCGGCCA AGGAGATCGT GTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	98.57	0.00e+00	3906.00
IUUC-Apl-003360	Anas platyrhynchos	90.70	0.00e+00	3542.00
IUUC-Ame-011681	Astyanax mexicanus	85.22	0.00e+00	3517.00
IUUC-Bta-012838	Bos taurus	96.26	0.00e+00	3875.00
IUUC-Cja-019068	Callithrix jacchus	96.21	0.00e+00	3855.00
IUUC-Cfa-020531	Canis familiaris	98.33	0.00e+00	3965.00
IUUC-Cpo-022304	Cavia porcellus	92.90	0.00e+00	3618.00
IUUC-Csa-023621	Chlorocebus sabaeus	95.37	0.00e+00	3510.00
IUUC-Cho-024944	Choloepus hoffmanni	76.65	0.00e+00	1498.00
IUUC-Dre-028772	Danio rerio	84.98	0.00e+00	3510.00
IUUC-Dno-030063	Dasypus novemcinctus	94.80	0.00e+00	3800.00
IUUC-Dor-030980	Dipodomys ordii	87.19	0.00e+00	1588.00
IUUC-Ete-032554	Echinops telfairi	93.56	0.00e+00	1045.00
IUUC-Eca-033909	Equus caballus	97.11	0.00e+00	3587.00
IUUC-Eeu-035180	Erinaceus europaeus	78.79	0.00e+00	1464.00
IUUC-Fal-037219	Ficedula albicollis	91.08	0.00e+00	3666.00
IUUC-Gmo-039146	Gadus morhua	80.69	0.00e+00	3313.00
IUUC-Gga-041095	Gallus gallus	91.14	0.00e+00	2657.00
IUUC-Gac-041341	Gasterosteus aculeatus	83.38	0.00e+00	3406.00
IUUC-Hsa-045997	Homo sapiens	96.46	0.00e+00	3863.00
IUUC-Lch-050306	Latimeria chalumnae	84.59	0.00e+00	3180.00
IUUC-Loc-052215	Lepisosteus oculatus	85.33	0.00e+00	3549.00
IUUC-Laf-054044	Loxodonta africana	94.95	0.00e+00	3824.00
IUUC-Mcc-054733	Macaca mulatta	96.41	0.00e+00	3860.00
IUUC-Mga-059666	Meleagris gallopavo	89.62	0.00e+00	3502.00
IUUC-Mmr-060995	Microcebus murinus	96.61	0.00e+00	3861.00
IUUC-Mdo-062482	Monodelphis domestica	92.92	0.00e+00	3769.00
IUUC-Mmu-063533	Mus musculus	95.55	0.00e+00	3806.00
IUUC-Mlu-067592	Myotis lucifugus	96.05	0.00e+00	3845.00
IUUC-Nle-069911	Nomascus leucogenys	96.16	0.00e+00	3844.00
IUUC-Ont-071966	Oreochromis niloticus	84.86	0.00e+00	3508.00
IUUC-Ola-086738	Oryzias latipes	84.01	0.00e+00	3458.00
IUUC-Oga-088436	Otolemur garnettii	93.45	0.00e+00	3748.00
IUUC-Oar-090153	Ovis aries	96.14	0.00e+00	3736.00
IUUC-Ptr-091008	Pan troglodytes	96.16	0.00e+00	3836.00
IUUC-Pan-092404	Papio anubis	95.95	0.00e+00	3832.00
IUUC-Psi-093417	Pelodiscus sinensis	90.18	0.00e+00	3523.00
IUUC-Ppa-095656	Physcomitrella patens	23.72	3.00e-17	84.70
IUUC-Pfo-096073	Poecilia formosa	84.83	0.00e+00	3507.00
IUUC-Pab-097900	Pongo abelii	95.85	0.00e+00	3838.00
IUUC-Pca-100107	Procavia capensis	80.58	0.00e+00	2527.00
IUUC-Pva-102880	Pteropus vampyrus	92.36	0.00e+00	3528.00
IUUC-Rno-106084	Rattus norvegicus	95.45	0.00e+00	3862.00
IUUC-Sha-106974	Sarcophilus harrisii	92.88	0.00e+00	3761.00
IUUC-Sar-113401	Sorex araneus	85.08	0.00e+00	1832.00
IUUC-Ssc-116057	Sus scrofa	96.62	0.00e+00	3786.00
IUUC-Tru-118444	Takifugu rubripes	83.50	0.00e+00	3425.00
IUUC-Tsy-118941	Tarsius syrichta	84.64	0.00e+00	2831.00
IUUC-Tni-120683	Tetraodon nigroviridis	83.22	0.00e+00	3274.00
IUUC-Tbe-127467	Tupaia belangeri	87.04	0.00e+00	1833.00
IUUC-Ttr-129138	Tursiops truncatus	92.31	0.00e+00	3545.00
IUUC-Vpa-130083	Vicugna pacos	90.63	0.00e+00	3451.00
IUUC-Xtr-131835	Xenopus tropicalis	88.09	0.00e+00	3641.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence