iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069911

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01193243

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000016938.1	ENSNLET00000021637.1	ENSNLEP00000020606.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-57	187.8	1698	1730
UBD/Beta-Prp	1.40e-139	464.4	726	940

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htd.svtclaf.sd.tllvsGsdDgtikvWDlr 31
           H d ++++la  ++ ++++s++ Dgt+++WD+ 
   Q: 1698 HVDgPIWGLAThPSrDFFLSAAEDGTVRLWDIA 1730
           5553699999898889***************75 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrslsgh.eaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd +i +wd++t k l+ l+gh + +v+av+fs dgk l++++ D  +ti +wd ++g+ +++ +g
   Q: 726  HDDDILCLTIHPLKDYVATGqvGRDPSIHIWDTETIKPLSILKGHhQYGVSAVDFSADGKRLASVGIDdsHTIVLWDWKKGEKLSIARG 814
           4555566************95569******************7651669***************99999******************** PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl 175
            +d++ +++++p+  dkl++++  +  + w    g  +       t  g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t 
   Q: 815  SKDKIFAVKMNPYVpDKLITAG-IKHMKFWRKAGGGLIGRngyigT-LGKNDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDIFLVKTV 899
           ************9978888887.9999***8888888877999844.5677799************************..889****** PP
   S: 176  tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
           +  h+++v s+   +  k +v+g++dg v lwd + ++c++t+ 
   Q: 900  KA-HDGPVFSMHALE--KGFVTGGKDGIVALWDDSFERCLKTYA 940
           98.********9888..67**********************996 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH 60
SDDIISLALH PERVLVATGQ VGKEPYICIW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGGGCATCC ACTTGACAGC CGGCGGCGCT CGCGGCCCTC AGCATGTTCC GCGAGGCGAG 60
GGTTTTCCTC CCGCCTGTGG GCTGAGGCGG CGGCGGCGGC CCCCGAAACG AGATGCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR011048--Haem_d1
IPR005108--HELP
IPR011041--Quinoprot_gluc/sorb_DH
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0003824--F:catalytic activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	96.21	0.00e+00	3821.00
IUUC-Apl-003360	Anas platyrhynchos	91.22	0.00e+00	3556.00
IUUC-Aca-004572	Anolis carolinensis	73.51	0.00e+00	3008.00
IUUC-Ame-011681	Astyanax mexicanus	85.11	0.00e+00	3502.00
IUUC-Bta-012838	Bos taurus	95.96	0.00e+00	3857.00
IUUC-Cja-019068	Callithrix jacchus	98.53	0.00e+00	3909.00
IUUC-Cfa-020531	Canis familiaris	96.61	0.00e+00	3902.00
IUUC-Cpo-022304	Cavia porcellus	93.20	0.00e+00	3631.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.21	1.00e-99	360.00
IUUC-Csa-023621	Chlorocebus sabaeus	98.53	0.00e+00	3588.00
IUUC-Cho-024944	Choloepus hoffmanni	83.56	0.00e+00	1308.00
IUUC-Cin-025205	Ciona intestinalis	58.57	0.00e+00	2410.00
IUUC-Csv-026014	Ciona savignyi	58.85	0.00e+00	2397.00
IUUC-Dre-028772	Danio rerio	84.76	0.00e+00	3498.00
IUUC-Dno-030063	Dasypus novemcinctus	94.90	0.00e+00	3800.00
IUUC-Dor-030980	Dipodomys ordii	86.76	0.00e+00	1576.00
IUUC-Ete-032554	Echinops telfairi	93.20	0.00e+00	1049.00
IUUC-Eca-033909	Equus caballus	96.68	0.00e+00	3564.00
IUUC-Eeu-035180	Erinaceus europaeus	79.38	0.00e+00	1467.00
IUUC-Fca-036307	Felis catus	74.89	0.00e+00	3061.00
IUUC-Fal-037219	Ficedula albicollis	91.58	0.00e+00	3679.00
IUUC-Gmo-039146	Gadus morhua	80.57	0.00e+00	3306.00
IUUC-Gga-041095	Gallus gallus	90.98	0.00e+00	2652.00
IUUC-Gac-041341	Gasterosteus aculeatus	83.11	0.00e+00	3397.00
IUUC-Ggo-045107	Gorilla gorilla	74.33	0.00e+00	3042.00
IUUC-Hsa-045997	Homo sapiens	99.19	0.00e+00	3926.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	73.49	0.00e+00	2957.00
IUUC-Lch-050306	Latimeria chalumnae	84.68	0.00e+00	3175.00
IUUC-Loc-052215	Lepisosteus oculatus	84.77	0.00e+00	3534.00
IUUC-Laf-054044	Loxodonta africana	95.10	0.00e+00	3825.00
IUUC-Mcc-054733	Macaca mulatta	99.04	0.00e+00	3921.00
IUUC-Meu-056618	Macropus eugenii	63.43	0.00e+00	1459.00
IUUC-Mga-059666	Meleagris gallopavo	89.57	0.00e+00	3490.00
IUUC-Mmr-060995	Microcebus murinus	97.67	0.00e+00	3886.00
IUUC-Mdo-062482	Monodelphis domestica	93.22	0.00e+00	3762.00
IUUC-Mmu-063533	Mus musculus	95.50	0.00e+00	3799.00
IUUC-Mpu-066704	Mustela putorius furo	96.16	0.00e+00	3869.00
IUUC-Mlu-067592	Myotis lucifugus	95.75	0.00e+00	3835.00
IUUC-Opr-070213	Ochotona princeps	73.56	0.00e+00	1621.00
IUUC-Ont-071966	Oreochromis niloticus	84.79	0.00e+00	3506.00
IUUC-Oan-073563	Ornithorhynchus anatinus	73.70	0.00e+00	3018.00
IUUC-Ocu-074531	Oryctolagus cuniculus	74.63	0.00e+00	3054.00
IUUC-Ola-086738	Oryzias latipes	84.14	0.00e+00	3458.00
IUUC-Olu-087860	Ostreococcus lucimarinus	37.75	6.00e-112	397.00
IUUC-Oga-088436	Otolemur garnettii	95.11	0.00e+00	3797.00
IUUC-Oar-090153	Ovis aries	95.98	0.00e+00	3728.00
IUUC-Ptr-091008	Pan troglodytes	98.89	0.00e+00	3901.00
IUUC-Pan-092404	Papio anubis	99.04	0.00e+00	3915.00
IUUC-Psi-093417	Pelodiscus sinensis	90.39	0.00e+00	3521.00
IUUC-Pma-094424	Petromyzon marinus	64.49	3.00e-113	400.00
IUUC-Pfo-096073	Poecilia formosa	84.86	0.00e+00	3509.00
IUUC-Pab-097900	Pongo abelii	98.68	0.00e+00	3905.00
IUUC-Pca-100107	Procavia capensis	81.13	0.00e+00	2543.00
IUUC-Pva-102880	Pteropus vampyrus	92.46	0.00e+00	3517.00
IUUC-Rno-106084	Rattus norvegicus	95.60	0.00e+00	3867.00
IUUC-Sha-106974	Sarcophilus harrisii	93.08	0.00e+00	3765.00
IUUC-Sar-113401	Sorex araneus	84.78	0.00e+00	1825.00
IUUC-Ssc-116057	Sus scrofa	95.99	0.00e+00	3768.00
IUUC-Tgu-116807	Taeniopygia guttata	74.43	0.00e+00	3009.00
IUUC-Tru-118444	Takifugu rubripes	83.49	0.00e+00	3424.00
IUUC-Tsy-118941	Tarsius syrichta	85.26	0.00e+00	2852.00
IUUC-Tni-120683	Tetraodon nigroviridis	83.10	0.00e+00	3272.00
IUUC-Tbe-127467	Tupaia belangeri	89.16	0.00e+00	1867.00
IUUC-Ttr-129138	Tursiops truncatus	92.35	0.00e+00	3537.00
IUUC-Vpa-130083	Vicugna pacos	90.83	0.00e+00	3447.00
IUUC-Xtr-131835	Xenopus tropicalis	88.09	0.00e+00	3635.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence