iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073563

UUCD1 version

UUC-OrA-00676

Ensembl Protein ID

ENSOANP00000017732.1

UniProt Accession

F7FJT4; F7FJT4_ORNAN

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000011192.3	ENSOANT00000017735.1	ENSOANP00000017732.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.70e-56	184.5	105	143
UBD/Beta-Prp	1.90e-130	434.6	730	947

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdD..gtikvWDlrtgvll 36
           Ht +v claf sd  +l+s + D  +ti +WD+++g+ll
   Q: 105  HTHGVACLAFdSDgQRLASVGLDakNTICIWDWKKGKLL 143
           99*********999*******9999**********9987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd+ i vwd+++ k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t +g
   Q: 730  HDDDILCLAIHPVKDFVATGqvGRDAAIHVWDTQSLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATTRG 818
           5555666************95569******************7789**********************77788889************* PP
   S: 93   hedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtlt 176
           h+d++  ++ +p   dklv+ +  + i+ w+   g   ++       g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t++
   Q: 819  HKDKIFVVKCNPHHvDKLVTVG-MKHIKFWQQAGGGFTSKrgifGSVGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDTLLLKTMK 904
           ************7769999988.99*****9888888887998777899999*************************..8899*****9 PP
   S: 177  gghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
             h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 905  A-HDGPVFAMHALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 947
           8.*********888..67*********************9997655 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MADRTAPRCQ LRLEWVYGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR EHSQRFFLGH 60
NDDIISLALH PDKTLVATGQ VGKDPYICLW DSYSVQTVSI LKDVHTHGVA CLAFDSDGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGATC GGACGGCTCC CCGATGCCAG CTGCGCCTCG AGTGGGTCTA CGGGTACAGG 60
GGCCACCAGT GCCGCAACAA CCTGTACTAC ACGGCGGGCA AGGAGGTGGT CTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR027295--Quinoprotein_ADH-like_fam
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0015630--C:microtubule cytoskeleton
GO:0008017--F:microtubule binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	95.57	0.00e+00	3773.00
IUUC-Apl-003604	Anas platyrhynchos	94.17	0.00e+00	3687.00
IUUC-Aca-004572	Anolis carolinensis	89.79	0.00e+00	3575.00
IUUC-Ame-010713	Astyanax mexicanus	80.55	0.00e+00	3212.00
IUUC-Bta-012812	Bos taurus	95.11	0.00e+00	3759.00
IUUC-Cja-019191	Callithrix jacchus	94.70	0.00e+00	3717.00
IUUC-Cfa-020041	Canis familiaris	95.97	0.00e+00	3511.00
IUUC-Cpo-022304	Cavia porcellus	71.61	0.00e+00	2853.00
IUUC-Cre-022931	Chlamydomonas reinhardtii	34.08	2.00e-100	362.00
IUUC-Csa-023689	Chlorocebus sabaeus	94.26	0.00e+00	3633.00
IUUC-Cho-025038	Choloepus hoffmanni	94.78	0.00e+00	1454.00
IUUC-Cin-025205	Ciona intestinalis	62.24	0.00e+00	2574.00
IUUC-Csv-026014	Ciona savignyi	63.76	0.00e+00	2602.00
IUUC-Dre-028772	Danio rerio	73.71	0.00e+00	3064.00
IUUC-Dno-029982	Dasypus novemcinctus	93.51	0.00e+00	3587.00
IUUC-Dor-030980	Dipodomys ordii	69.07	0.00e+00	1288.00
IUUC-Ete-032554	Echinops telfairi	71.20	0.00e+00	823.00
IUUC-Eca-034161	Equus caballus	93.65	0.00e+00	3586.00
IUUC-Eeu-035180	Erinaceus europaeus	63.19	0.00e+00	1143.00
IUUC-Fca-036307	Felis catus	95.47	0.00e+00	3771.00
IUUC-Fal-037332	Ficedula albicollis	92.56	0.00e+00	3606.00
IUUC-Gmo-039057	Gadus morhua	74.81	0.00e+00	2988.00
IUUC-Gga-041095	Gallus gallus	74.24	0.00e+00	2212.00
IUUC-Gac-042555	Gasterosteus aculeatus	80.05	0.00e+00	3216.00
IUUC-Ggo-045107	Gorilla gorilla	95.21	0.00e+00	3763.00
IUUC-Hsa-046482	Homo sapiens	95.32	0.00e+00	3765.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	93.24	0.00e+00	3630.00
IUUC-Lch-050306	Latimeria chalumnae	72.81	0.00e+00	2735.00
IUUC-Loc-052642	Lepisosteus oculatus	88.12	0.00e+00	3457.00
IUUC-Laf-053649	Loxodonta africana	93.13	0.00e+00	3648.00
IUUC-Mcc-055361	Macaca mulatta	95.12	0.00e+00	3294.00
IUUC-Meu-056618	Macropus eugenii	78.54	0.00e+00	1790.00
IUUC-Mga-059202	Meleagris gallopavo	93.22	0.00e+00	3572.00
IUUC-Mmr-060729	Microcebus murinus	92.94	0.00e+00	3719.00
IUUC-Mdo-062462	Monodelphis domestica	95.32	0.00e+00	3656.00
IUUC-Mmu-063865	Mus musculus	94.09	0.00e+00	3739.00
IUUC-Mpu-066724	Mustela putorius furo	95.72	0.00e+00	3776.00
IUUC-Mlu-067816	Myotis lucifugus	94.77	0.00e+00	3754.00
IUUC-Nle-069911	Nomascus leucogenys	73.70	0.00e+00	3047.00
IUUC-Opr-070213	Ochotona princeps	91.36	0.00e+00	1939.00
IUUC-Ont-071928	Oreochromis niloticus	79.44	0.00e+00	3224.00
IUUC-Ocu-074531	Oryctolagus cuniculus	95.16	0.00e+00	3759.00
IUUC-Ola-086943	Oryzias latipes	78.40	0.00e+00	3113.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	5.00e-119	421.00
IUUC-Oga-088665	Otolemur garnettii	94.23	0.00e+00	3613.00
IUUC-Oar-090429	Ovis aries	95.37	0.00e+00	3768.00
IUUC-Ptr-091168	Pan troglodytes	86.65	0.00e+00	3362.00
IUUC-Pan-092404	Papio anubis	73.77	0.00e+00	3046.00
IUUC-Psi-093281	Pelodiscus sinensis	92.09	0.00e+00	3638.00
IUUC-Pma-094424	Petromyzon marinus	71.01	2.00e-122	431.00
IUUC-Pfo-096150	Poecilia formosa	79.67	0.00e+00	3110.00
IUUC-Pab-098561	Pongo abelii	95.65	0.00e+00	3266.00
IUUC-Pca-100107	Procavia capensis	63.33	0.00e+00	1910.00
IUUC-Pva-102880	Pteropus vampyrus	70.79	0.00e+00	2782.00
IUUC-Rno-105002	Rattus norvegicus	93.33	0.00e+00	3728.00
IUUC-Sha-107105	Sarcophilus harrisii	92.70	0.00e+00	3540.00
IUUC-Sar-113401	Sorex araneus	68.54	0.00e+00	770.00
IUUC-Ssc-116282	Sus scrofa	95.27	0.00e+00	3655.00
IUUC-Tgu-116807	Taeniopygia guttata	93.74	0.00e+00	3675.00
IUUC-Tru-118040	Takifugu rubripes	78.99	0.00e+00	3172.00
IUUC-Tsy-118941	Tarsius syrichta	64.05	0.00e+00	2220.00
IUUC-Tni-120118	Tetraodon nigroviridis	76.66	0.00e+00	3149.00
IUUC-Tbe-127467	Tupaia belangeri	68.60	0.00e+00	1455.00
IUUC-Ttr-129138	Tursiops truncatus	70.72	0.00e+00	2784.00
IUUC-Vpa-130083	Vicugna pacos	70.12	0.00e+00	2692.00
IUUC-Xtr-131835	Xenopus tropicalis	72.97	0.00e+00	3076.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence