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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063727
UUCD1 version UUC-MuM-00270
Ensembl Protein ID ENSMUSP00000049331.9
UniProt Accession O54965; O54966; Q6PEA8; RNF13_MOUSE
Genbank Protein ID AAC03770.1; AAC03771.1; BAE34334.1; EDL35322.1; EDL35326.1; AAH58182.1
Protein Name E3 ubiquitin-protein ligase RNF13; RING finger protein 13; RING-type E3 ubiquitin transferase RNF13
Genbank Nucleotide ID AF037205; AF037206; AK158046; CH466530; CH466530; BC058182
Gene Name Rnf13; Rzf
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000036503.13 ENSMUST00000041826.13 ENSMUSP00000049331.9
ENSMUSG00000036503.13 ENSMUST00000200497.4 ENSMUSP00000142462.1
ENSMUSG00000036503.13 ENSMUST00000198214.4 ENSMUSP00000143498.1
ENSMUSG00000036503.13 ENSMUST00000197205.4 ENSMUSP00000143692.1
ENSMUSG00000036503.13 ENSMUST00000198249.4 ENSMUSP00000142828.1
ENSMUSG00000036503.13 ENSMUST00000199041.1 ENSMUSP00000142335.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 9.90e-09 36.7 240 282
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdg..plvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiCle+++dg  +++lpC H++h +C+  w     +++++ +CP+C+
   Q: 240  CAICLEEYEDGdkLRILPCSHAYHCKCVDPW-----LTKTKKTCPVCK 282
           ********66666******************.....899********7 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation.
 E3 ubiquitin-protein ligase that may play a role in controlling cell proliferation.
Protein Sequence
(Fasta)
MLLSIGMLML SATQVYTILT VQLFAFLNLL PVEADILAYN FENASQTFED LPARFGYRLP 60
AEGLKGFLIN SKPENACEPI VPPPLKDNSS GTFIVLIRRL DCNFDIKVLN AQRAGYKAAI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063727|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGACTTCCG CTTGCCCGCT GTTGTGGTCC CTTCTCCGAC TTGCTTGGGT AGGGGCTCAG 60
TGCGGATACT CAGTCATGAA GTCCGGGTAG CGACTTCTCT TGGGTGGCCG TGAGCCTAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063727|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0967--Endosome
KW-0325--Glycoprotein
KW-0458--Lysosome
KW-0472--Membrane
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0732--Signal
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003137--PA_domain
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50089--ZF_RING_2
Pfam

PF02225--PA
PF13639--zf-RING_2
SMART

SM00184--RING
Gene Ontology

GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0043231--C:intracellular membrane-bounded organelle
GO:0031902--C:late endosome membrane
GO:0005765--C:lysosomal membrane
GO:0005637--C:nuclear inner membrane
GO:0005654--C:nucleoplasm
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0051865--P:protein autoubiquitination
KEGG mmu:24017
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000889 Aegilops tauschii 26.94 4.00e-17 83.20
IUUC-Aml-001909 Ailuropoda melanoleuca 94.23 0.00e+00 627.00
IUUC-Atr-003055 Amborella trichopoda 31.10 5.00e-31 128.00
IUUC-Apl-004022 Anas platyrhynchos 87.93 3.00e-168 584.00
IUUC-Aca-004641 Anolis carolinensis 86.46 9.00e-167 579.00
IUUC-Aly-006519 Arabidopsis lyrata 33.46 4.00e-33 135.00
IUUC-Ath-006590 Arabidopsis thaliana 33.07 7.00e-32 130.00
IUUC-Acl-008221 Aspergillus clavatus 54.00 4.00e-13 70.50
IUUC-Afl-008383 Aspergillus flavus 52.00 6.00e-13 69.70
IUUC-Afu-008769 Aspergillus fumigatus 52.00 7.00e-13 69.70
IUUC-Ani-009337 Aspergillus nidulans 35.56 1.00e-13 69.70
IUUC-Ate-010334 Aspergillus terreus 52.00 6.00e-13 69.70
IUUC-Ame-010635 Astyanax mexicanus 69.89 9.00e-136 476.00
IUUC-Bgr-012131 Blumeria graminis 52.00 6.00e-13 69.70
IUUC-Bta-012593 Bos taurus 93.96 0.00e+00 665.00
IUUC-Bci-013936 Botrytis cinerea 36.49 3.00e-13 70.10
IUUC-Bdi-014479 Brachypodium distachyon 33.60 7.00e-29 120.00
IUUC-Bol-015396 Brassica oleracea 34.14 7.00e-23 101.00
IUUC-Bra-016728 Brassica rapa 32.65 2.00e-33 137.00
IUUC-Cel-018181 Caenorhabditis elegans 31.72 8.00e-29 121.00
IUUC-Cja-019353 Callithrix jacchus 92.91 8.00e-178 616.00
IUUC-Cfa-020234 Canis familiaris 94.49 0.00e+00 627.00
IUUC-Cpo-021602 Cavia porcellus 91.84 2.00e-153 535.00
IUUC-Csa-023201 Chlorocebus sabaeus 93.18 1.00e-178 619.00
IUUC-Cho-024954 Choloepus hoffmanni 79.00 5.00e-144 503.00
IUUC-Cin-025554 Ciona intestinalis 42.81 3.00e-61 228.00
IUUC-Dre-028744 Danio rerio 76.00 2.00e-133 468.00
IUUC-Dno-029675 Dasypus novemcinctus 93.44 8.00e-180 622.00
IUUC-Dor-030791 Dipodomys ordii 77.95 8.00e-135 473.00
IUUC-Dse-031406 Dothistroma septosporum 45.00 5.00e-13 70.10
IUUC-Dme-031765 Drosophila melanogaster 40.07 1.00e-51 197.00
IUUC-Ete-032577 Echinops telfairi 84.28 3.00e-136 478.00
IUUC-Eca-034148 Equus caballus 92.91 1.00e-178 619.00
IUUC-Eeu-034552 Erinaceus europaeus 92.65 6.00e-175 606.00
IUUC-Fca-036021 Felis catus 94.23 2.00e-180 625.00
IUUC-Fal-037621 Ficedula albicollis 86.88 2.00e-165 575.00
IUUC-Gmo-039485 Gadus morhua 75.70 7.00e-130 456.00
IUUC-Ggr-039824 Gaeumannomyces graminis 52.00 1.00e-12 68.90
IUUC-Gga-041166 Gallus gallus 87.93 3.00e-169 587.00
IUUC-Gac-042124 Gasterosteus aculeatus 73.75 2.00e-125 441.00
IUUC-Ggo-045344 Gorilla gorilla 93.44 3.00e-179 620.00
IUUC-Hsa-045960 Homo sapiens 93.44 3.00e-179 620.00
IUUC-Itr-048327 Ictidomys tridecemlineatus 92.65 6.00e-178 616.00
IUUC-Lch-050635 Latimeria chalumnae 80.62 5.00e-132 464.00
IUUC-Loc-052869 Lepisosteus oculatus 76.76 1.00e-137 482.00
IUUC-Lma-053120 Leptosphaeria maculans 43.75 1.00e-13 72.00
IUUC-Laf-054477 Loxodonta africana 90.81 2.00e-176 611.00
IUUC-Mcc-055232 Macaca mulatta 93.18 1.00e-178 619.00
IUUC-Meu-056237 Macropus eugenii 81.99 3.00e-115 407.00
IUUC-Mor-057005 Magnaporthe oryzae 52.00 1.00e-12 68.90
IUUC-Mpo-057523 Magnaporthe poae 52.00 1.00e-12 68.60
IUUC-Mtr-058129 Medicago truncatula 32.03 1.00e-27 117.00
IUUC-Mla-059171 Melampsora laricipopulina 42.59 2.00e-10 60.80
IUUC-Mga-059780 Meleagris gallopavo 87.93 6.00e-169 586.00
IUUC-Mvi-060468 Microbotryum violaceum 46.00 5.00e-12 66.60
IUUC-Mmr-061384 Microcebus murinus 93.78 9.00e-174 602.00
IUUC-Mdo-062781 Monodelphis domestica 89.27 5.00e-174 603.00
IUUC-Mac-064645 Musa acuminata 32.46 6.00e-30 125.00
IUUC-Mpu-066497 Mustela putorius furo 94.75 0.00e+00 627.00
IUUC-Mlu-067654 Myotis lucifugus 94.85 2.00e-114 404.00
IUUC-Nfi-068444 Neosartorya fischeri 52.00 1.00e-12 68.90
IUUC-Ncr-068802 Neurospora crassa 43.59 7.00e-14 72.80
IUUC-Nle-069368 Nomascus leucogenys 93.44 3.00e-179 620.00
IUUC-Opr-070934 Ochotona princeps 65.35 8.00e-106 377.00
IUUC-Ont-071868 Oreochromis niloticus 73.35 1.00e-124 439.00
IUUC-Oan-072733 Ornithorhynchus anatinus 84.34 2.00e-101 362.00
IUUC-Ocu-074083 Oryctolagus cuniculus 92.91 1.00e-178 619.00
IUUC-Ogu-078205 Oryza glumaepatula 34.39 3.00e-28 119.00
IUUC-Ola-086440 Oryzias latipes 71.71 3.00e-112 398.00
IUUC-Oga-088291 Otolemur garnettii 88.68 2.00e-162 565.00
IUUC-Oar-089911 Ovis aries 93.96 0.00e+00 666.00
IUUC-Ptr-091166 Pan troglodytes 93.44 3.00e-179 620.00
IUUC-Pan-092154 Papio anubis 93.18 1.00e-178 619.00
IUUC-Psi-093062 Pelodiscus sinensis 87.66 2.00e-164 571.00
IUUC-Pma-094545 Petromyzon marinus 75.00 3.00e-26 109.00
IUUC-Pno-094874 Phaeosphaeria nodorum 49.06 3.00e-13 70.10
IUUC-Ppa-095268 Physcomitrella patens 30.60 9.00e-28 117.00
IUUC-Pfo-097232 Poecilia formosa 74.92 1.00e-128 452.00
IUUC-Pab-097909 Pongo abelii 93.18 2.00e-179 621.00
IUUC-Pop-099688 Populus trichocarpa 32.08 3.00e-23 102.00
IUUC-Pca-100724 Procavia capensis 76.42 2.00e-133 468.00
IUUC-Pva-102624 Pteropus vampyrus 88.19 1.00e-160 558.00
IUUC-Pgr-103420 Puccinia graminis 53.19 9.00e-12 66.20
IUUC-Ptt-103943 Puccinia triticina 44.44 7.00e-11 62.00
IUUC-Pte-104044 Pyrenophora teres 49.09 9.00e-14 72.00
IUUC-Pyt-104819 Pyrenophora triticirepentis 50.00 2.00e-13 71.20
IUUC-Rno-105109 Rattus norvegicus 97.38 1.00e-172 598.00
IUUC-Sha-107563 Sarcophilus harrisii 89.27 9.00e-170 589.00
IUUC-Ssl-108601 Sclerotinia sclerotiorum 42.86 4.00e-13 69.30
IUUC-Smo-109031 Selaginella moellendorffii 31.79 4.00e-39 154.00
IUUC-Sly-110842 Solanum lycopersicum 29.39 3.00e-28 119.00
IUUC-Stu-112408 Solanum tuberosum 30.65 7.00e-28 118.00
IUUC-Sre-114989 Sporisorium reilianum 45.10 4.00e-13 70.50
IUUC-Ssc-116043 Sus scrofa 93.96 1.00e-179 622.00
IUUC-Tgu-116908 Taeniopygia guttata 86.65 5.00e-166 577.00
IUUC-Tru-118219 Takifugu rubripes 73.90 2.00e-128 452.00
IUUC-Tsy-119333 Tarsius syrichta 93.96 1.00e-178 618.00
IUUC-Tni-120332 Tetraodon nigroviridis 67.58 1.00e-83 302.00
IUUC-Tre-122208 Trichoderma reesei 52.00 1.00e-12 68.60
IUUC-Tvi-122495 Trichoderma virens 43.75 9.00e-13 68.60
IUUC-Tae-125320 Triticum aestivum 31.88 6.00e-30 124.00
IUUC-Tur-126455 Triticum urartu 31.88 6.00e-26 112.00
IUUC-Tme-126894 Tuber melanosporum 39.47 1.00e-12 68.20
IUUC-Tbe-127859 Tupaia belangeri 83.68 3.00e-162 564.00
IUUC-Ttr-129219 Tursiops truncatus 84.25 3.00e-152 531.00
IUUC-Uma-129559 Ustilago maydis 52.08 1.00e-12 68.20
IUUC-Vda-129915 Verticillium dahliae 52.00 5.00e-13 69.70
IUUC-Vpa-130314 Vicugna pacos 91.34 5.00e-169 587.00
IUUC-Xtr-132114 Xenopus tropicalis 74.72 4.00e-130 457.00
IUUC-Xma-133474 Xiphophorus maculatus 74.92 7.00e-129 453.00
IUUC-Yli-134442 Yarrowia lipolytica 46.81 1.00e-12 67.00
Created Date 25-Jun-2017

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