iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oan-073050

Ensembl Protein ID

ENSOANP00000010327.2

UniProt Accession

F6R3T5; F6R3T5_ORNAN

Protein Name

Uncharacterized protein

Gene Name

SIK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000006466.2	ENSOANT00000010329.2	ENSOANP00000010327.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	75.23	0.00e+00	892.00	IUUC-Hsa-046775

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MVIMSDFTSV PISSHIQQRP LRVGFYDIER TLGKGNFAVV KLARHRVTKT QVAIKIIDKT 60
RLDSSNLEKI YREVQIMKLL NHPHIIKLYQ VMETKDMLYI VTEFAKNGEM FDYLTSNGHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCAGCAGGG GCAGCAGGTC CTCCAGCGGG GAAGGGAACG GGTAGCAGCT CCCTCCCACC 60
CGGTCCGCGC TTCCCCGGCG GACCCTCCTG CTCTCACACT CGCACCTTCT CTCTCACTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR034672--SIK
IPR015940--UBA

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0043276--P:anoikis
GO:0055007--P:cardiac muscle cell differentiation
GO:0032870--P:cellular response to hormone stimulus
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0035556--P:intracellular signal transduction
GO:0032792--P:negative regulation of CREB transcription factor activity
GO:0045721--P:negative regulation of gluconeogenesis
GO:0010868--P:negative regulation of triglyceride biosynthetic process
GO:0006468--P:protein phosphorylation
GO:0007346--P:regulation of mitotic cell cycle
GO:0010830--P:regulation of myotube differentiation

KEGG

oaa:100081047

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001538	Ailuropoda melanoleuca	47.64	3.00e-127	448.00
IUUC-Aca-004739	Anolis carolinensis	79.56	0.00e+00	980.00
IUUC-Ame-011603	Astyanax mexicanus	63.82	0.00e+00	769.00
IUUC-Cfa-020801	Canis familiaris	66.38	0.00e+00	850.00
IUUC-Cpo-022296	Cavia porcellus	74.64	0.00e+00	852.00
IUUC-Csa-023676	Chlorocebus sabaeus	74.31	0.00e+00	874.00
IUUC-Cho-025021	Choloepus hoffmanni	71.03	2.00e-148	518.00
IUUC-Cin-025762	Ciona intestinalis	43.16	6.00e-127	447.00
IUUC-Csv-026013	Ciona savignyi	58.58	1.00e-119	421.00
IUUC-Dre-028021	Danio rerio	65.88	0.00e+00	769.00
IUUC-Dno-029103	Dasypus novemcinctus	70.03	0.00e+00	714.00
IUUC-Dme-031957	Drosophila melanogaster	62.10	4.00e-128	452.00
IUUC-Ete-033190	Echinops telfairi	78.60	0.00e+00	675.00
IUUC-Gmo-039423	Gadus morhua	62.59	0.00e+00	755.00
IUUC-Gga-040174	Gallus gallus	73.46	0.00e+00	1001.00
IUUC-Gac-041875	Gasterosteus aculeatus	53.45	4.00e-169	588.00
IUUC-Ggo-045090	Gorilla gorilla	74.39	0.00e+00	863.00
IUUC-Hsa-046775	Homo sapiens	75.15	0.00e+00	872.00
IUUC-Itr-048715	Ictidomys tridecemlineatus	73.84	0.00e+00	884.00
IUUC-Lch-049933	Latimeria chalumnae	62.64	0.00e+00	874.00
IUUC-Loc-052048	Lepisosteus oculatus	68.34	0.00e+00	800.00
IUUC-Laf-054466	Loxodonta africana	76.54	0.00e+00	915.00
IUUC-Mcc-054655	Macaca mulatta	74.46	0.00e+00	872.00
IUUC-Meu-056705	Macropus eugenii	80.44	0.00e+00	901.00
IUUC-Mmr-061419	Microcebus murinus	75.31	0.00e+00	905.00
IUUC-Mdo-062854	Monodelphis domestica	76.71	0.00e+00	896.00
IUUC-Mmu-064252	Mus musculus	75.51	0.00e+00	930.00
IUUC-Nle-069329	Nomascus leucogenys	75.00	0.00e+00	788.00
IUUC-Opr-071101	Ochotona princeps	62.30	5.00e-168	583.00
IUUC-Ont-071887	Oreochromis niloticus	63.48	0.00e+00	743.00
IUUC-Oga-088220	Otolemur garnettii	73.53	0.00e+00	887.00
IUUC-Oar-089420	Ovis aries	74.17	0.00e+00	775.00
IUUC-Ptr-091258	Pan troglodytes	75.15	0.00e+00	870.00
IUUC-Pan-092031	Papio anubis	74.38	0.00e+00	872.00
IUUC-Pfo-097451	Poecilia formosa	63.83	0.00e+00	738.00
IUUC-Pab-097806	Pongo abelii	75.15	0.00e+00	871.00
IUUC-Pva-102182	Pteropus vampyrus	67.75	0.00e+00	661.00
IUUC-Sha-107262	Sarcophilus harrisii	78.59	0.00e+00	973.00
IUUC-Ssc-115584	Sus scrofa	91.53	1.00e-137	481.00
IUUC-Tgu-116973	Taeniopygia guttata	79.72	0.00e+00	962.00
IUUC-Tsy-119567	Tarsius syrichta	46.57	6.00e-117	414.00
IUUC-Ttr-128365	Tursiops truncatus	73.22	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence