iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052790

Ensembl Protein ID

ENSLOCP00000016462.1

UniProt Accession

W5N753; W5N753_LEPOC

Genbank Protein ID

ENSLOCP00000016462

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01026108

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000013355.1	ENSLOCT00000016492.1	ENSLOCP00000016462.1
ENSLOCG00000013355.1	ENSLOCT00000016496.1	ENSLOCP00000016465.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-39	132.1	279	315
UBD/Beta-Prp	1.80e-52	178.6	188	392

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           +H+++++++++ ++ + ++sGsdD t++++Dlr ++ 
   Q: 279  THESDINSVRYyPSgDAFASGSDDATCRLYDLRADRE 315
           5*********99666*****************99875 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqclee 131
            +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vlsl++ p  +g+++vsG+ d+ ++vwdl++gqc++ 
   Q: 188  KKSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHAADVLSLDLAPseTGNTFVSGGCDKKAMVWDLRSGQCIQ- 275
           4677889999*********99***************************************9777************************. PP
   S: 132  tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l 
   Q: 276  SFETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGTRVSILF 364
           *******************************************95333556778999******************************** PP
   S: 220  ghtdnvksvrfspnderlvsgssDgsir 247
           gh++ v+ +r+sp+++ + sgs D ++r
   Q: 365  GHENRVSTLRVSPDGTAFCSGSWDHTLR 392
           **********************999986 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MCDQTFLAIN FGPCDKCQKT KPLMNIYIKS EPINYCALCV ELMATEGLQE SETLASLKNE 60
SETLKSKLEE ERAKLHDVEL HQVADRVEAL GQFVMKTRRT LKGHGNKVLC MDWCKDKRRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGATCTTTA ATACCCTCTA AGTAGCTTAC AAGTCAGTCC TTCATATTCA ATTCTCTTTA 60
CCCCCTGCAC ATGAAACGCA GCCTCTGTAA AGACACAAAG AGTTCTTCTC GGACAAGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR002475--Bcl2-like
IPR026298--Blc2_fam
IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50062--BCL2_FAMILY
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00452--Bcl-2
PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0042981--P:regulation of apoptotic process
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	83.93	0.00e+00	702.00
IUUC-Apl-003399	Anas platyrhynchos	96.81	0.00e+00	642.00
IUUC-Aca-004861	Anolis carolinensis	91.84	0.00e+00	761.00
IUUC-Ame-011851	Astyanax mexicanus	93.14	0.00e+00	688.00
IUUC-Bta-012438	Bos taurus	94.57	0.00e+00	700.00
IUUC-Cel-018408	Caenorhabditis elegans	64.62	2.00e-138	485.00
IUUC-Cja-019086	Callithrix jacchus	90.56	0.00e+00	753.00
IUUC-Cfa-021255	Canis familiaris	88.52	0.00e+00	706.00
IUUC-Cpo-021398	Cavia porcellus	89.57	0.00e+00	744.00
IUUC-Csa-023776	Chlorocebus sabaeus	95.14	0.00e+00	703.00
IUUC-Cin-025305	Ciona intestinalis	57.85	1.00e-129	456.00
IUUC-Csv-026058	Ciona savignyi	57.49	2.00e-128	452.00
IUUC-Dre-028432	Danio rerio	89.29	0.00e+00	712.00
IUUC-Dno-029958	Dasypus novemcinctus	75.86	3.00e-130	457.00
IUUC-Dor-031013	Dipodomys ordii	96.84	4.00e-149	520.00
IUUC-Dme-031889	Drosophila melanogaster	67.54	1.00e-146	512.00
IUUC-Ete-033033	Echinops telfairi	64.03	1.00e-141	496.00
IUUC-Eca-033977	Equus caballus	86.22	0.00e+00	713.00
IUUC-Eeu-035079	Erinaceus europaeus	89.46	0.00e+00	734.00
IUUC-Fca-035693	Felis catus	84.26	0.00e+00	703.00
IUUC-Fal-037345	Ficedula albicollis	94.86	0.00e+00	702.00
IUUC-Gmo-039222	Gadus morhua	92.86	0.00e+00	655.00
IUUC-Gga-040320	Gallus gallus	96.00	0.00e+00	707.00
IUUC-Gac-042644	Gasterosteus aculeatus	92.07	0.00e+00	684.00
IUUC-Ggo-044489	Gorilla gorilla	86.80	0.00e+00	714.00
IUUC-Hsa-046434	Homo sapiens	90.56	0.00e+00	753.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	91.11	3.00e-173	600.00
IUUC-Laf-054255	Loxodonta africana	89.29	0.00e+00	746.00
IUUC-Mcc-055610	Macaca mulatta	90.56	0.00e+00	753.00
IUUC-Meu-056819	Macropus eugenii	80.87	0.00e+00	656.00
IUUC-Mga-059740	Meleagris gallopavo	86.68	0.00e+00	711.00
IUUC-Mmr-061221	Microcebus murinus	90.31	0.00e+00	749.00
IUUC-Mdo-062619	Monodelphis domestica	96.00	0.00e+00	707.00
IUUC-Mmu-064266	Mus musculus	90.31	0.00e+00	753.00
IUUC-Mpu-065766	Mustela putorius furo	96.31	2.00e-176	611.00
IUUC-Mlu-067221	Myotis lucifugus	84.01	0.00e+00	692.00
IUUC-Nle-069515	Nomascus leucogenys	96.49	0.00e+00	641.00
IUUC-Opr-070195	Ochotona princeps	82.31	0.00e+00	660.00
IUUC-Ont-071535	Oreochromis niloticus	82.40	2.00e-179	621.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.28	2.00e-105	374.00
IUUC-Ocu-074666	Oryctolagus cuniculus	96.98	5.00e-177	613.00
IUUC-Ola-087428	Oryzias latipes	82.74	0.00e+00	635.00
IUUC-Oga-089090	Otolemur garnettii	90.10	0.00e+00	748.00
IUUC-Oar-090017	Ovis aries	85.42	0.00e+00	692.00
IUUC-Ptr-091280	Pan troglodytes	82.40	0.00e+00	669.00
IUUC-Pan-092198	Papio anubis	95.87	0.00e+00	641.00
IUUC-Psi-093030	Pelodiscus sinensis	85.71	0.00e+00	719.00
IUUC-Pma-094140	Petromyzon marinus	80.28	2.00e-102	364.00
IUUC-Pfo-096685	Poecilia formosa	82.65	0.00e+00	636.00
IUUC-Pab-098157	Pongo abelii	95.43	0.00e+00	706.00
IUUC-Pca-100988	Procavia capensis	70.10	2.00e-154	538.00
IUUC-Pva-102232	Pteropus vampyrus	82.29	2.00e-170	591.00
IUUC-Rno-105526	Rattus norvegicus	91.24	0.00e+00	670.00
IUUC-Sce-106298	Saccharomyces cerevisiae	35.92	9.00e-67	247.00
IUUC-Sha-106754	Sarcophilus harrisii	91.58	0.00e+00	715.00
IUUC-Ssc-115390	Sus scrofa	90.33	0.00e+00	748.00
IUUC-Tgu-117377	Taeniopygia guttata	85.13	0.00e+00	691.00
IUUC-Tru-117905	Takifugu rubripes	71.77	0.00e+00	769.00
IUUC-Tsy-119392	Tarsius syrichta	76.28	2.00e-173	601.00
IUUC-Tni-119834	Tetraodon nigroviridis	77.30	2.00e-174	605.00
IUUC-Tbe-127469	Tupaia belangeri	88.98	0.00e+00	688.00
IUUC-Ttr-128252	Tursiops truncatus	88.04	0.00e+00	714.00
IUUC-Vpa-130173	Vicugna pacos	72.92	6.00e-145	506.00
IUUC-Xtr-131803	Xenopus tropicalis	92.60	0.00e+00	736.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence