iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091280

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AACZ03098515

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000007084.5	ENSPTRT00000013073.4	ENSPTRP00000012110.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.50e-43	142.5	197	237
UBD/Beta-Prp	1.10e-54	185.6	151	356

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf....sdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++v cl++    +++++vsG+ D++ +vWD+r+g +++
   Q: 197  GHGADVLCLDLapseTGNTFVSGGCDKKAMVWDMRSGQCVQ 237
           8***********9644499********************98 PP

UBD/Beta-Prp

   S: 46   rslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp..sgdklvsGshdrtirvwdletgqcleet 132
           +s+  h++  +a++f +++  ++t+s D+t  +wd+++g+ +++++gh ++vl+l++ p  +g+++vsG+ d+ ++vwd+++gqc++  
   Q: 151  KSVAMHTNYLSACSFTNSDMQILTASGDGTCALWDVESGQLLQSFHGHGADVLCLDLAPseTGNTFVSGGCDKKAMVWDMRSGQCVQ-A 238
           567889999*********99***************************************9778************************.* PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.tgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
           ++ h++ +n+v++ p+g+ ++sGs+D t+rl+dl+ ++ +    ++       s++f+ +g+ l +g +d t+++wd+ +g+ v +l g
   Q: 239  FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYsKESIIFGASSVDFSLSGRLLFAGYNDYTINVWDVLKGSRVSILFG 327
           *******************************************5333556778999********************************* PP
   S: 221  htdnvksvrfspnderlvsgssDgsiriW 249
           h++ v+ +r+sp+++ + sgs D ++r+W
   Q: 328  HENRVSTLRVSPDGTAFCSGSWDHTLRVW 356
           ***************************** PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MCDQTFLVNV FGSCDKCFKQ RALRPVFKKS QQLSYCSTCA EIHQVAERVE ALGQFVMKTR 60
RTLKGHGNKV LCMDWCKDKR RIVSSSQDGK VIVWDSFTTN KEHAVTMPCT WVMACAYAPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTGTGATC AGACCTTTCT CGTTAATGTA TTTGGCTCAT GTGACAAATG TTTCAAACAA 60
CGAGCTCTGA GACCAGTTTT CAAGAAGTCT CAACAACTCA GCTACTGTTC AACATGTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005096--F:GTPase activator activity
GO:1901386--P:negative regulation of voltage-gated calcium channel activity
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001811	Ailuropoda melanoleuca	90.13	0.00e+00	727.00
IUUC-Apl-003399	Anas platyrhynchos	98.72	0.00e+00	648.00
IUUC-Aca-004861	Anolis carolinensis	84.56	0.00e+00	694.00
IUUC-Ame-011851	Astyanax mexicanus	94.92	0.00e+00	639.00
IUUC-Bta-012438	Bos taurus	99.37	0.00e+00	662.00
IUUC-Cel-018408	Caenorhabditis elegans	64.85	8.00e-131	459.00
IUUC-Cja-019086	Callithrix jacchus	90.33	0.00e+00	725.00
IUUC-Cfa-021255	Canis familiaris	90.33	0.00e+00	723.00
IUUC-Cpo-021398	Cavia porcellus	88.64	0.00e+00	712.00
IUUC-Csa-023776	Chlorocebus sabaeus	99.68	0.00e+00	664.00
IUUC-Cin-025305	Ciona intestinalis	58.82	1.00e-123	436.00
IUUC-Csv-026058	Ciona savignyi	59.13	3.00e-122	431.00
IUUC-Dre-028432	Danio rerio	77.72	0.00e+00	640.00
IUUC-Dno-029958	Dasypus novemcinctus	79.31	4.00e-130	456.00
IUUC-Dor-031013	Dipodomys ordii	99.22	3.00e-152	530.00
IUUC-Dme-031889	Drosophila melanogaster	68.35	5.00e-138	483.00
IUUC-Ete-033033	Echinops telfairi	69.64	8.00e-150	523.00
IUUC-Eca-033977	Equus caballus	89.87	0.00e+00	721.00
IUUC-Eeu-035079	Erinaceus europaeus	89.03	0.00e+00	709.00
IUUC-Fca-035693	Felis catus	89.67	0.00e+00	723.00
IUUC-Fal-037345	Ficedula albicollis	98.11	0.00e+00	657.00
IUUC-Gmo-039222	Gadus morhua	93.69	0.00e+00	636.00
IUUC-Gga-040320	Gallus gallus	98.42	0.00e+00	659.00
IUUC-Gac-042644	Gasterosteus aculeatus	94.01	0.00e+00	639.00
IUUC-Ggo-044489	Gorilla gorilla	89.65	0.00e+00	725.00
IUUC-Hsa-046434	Homo sapiens	90.38	0.00e+00	729.00
IUUC-Itr-048771	Ictidomys tridecemlineatus	94.27	8.00e-176	608.00
IUUC-Loc-052790	Lepisosteus oculatus	82.40	0.00e+00	668.00
IUUC-Laf-054255	Loxodonta africana	88.80	0.00e+00	712.00
IUUC-Mcc-055610	Macaca mulatta	90.08	0.00e+00	723.00
IUUC-Meu-056819	Macropus eugenii	86.48	0.00e+00	684.00
IUUC-Mga-059740	Meleagris gallopavo	84.29	0.00e+00	693.00
IUUC-Mmr-061221	Microcebus murinus	90.13	0.00e+00	727.00
IUUC-Mdo-062619	Monodelphis domestica	99.05	0.00e+00	662.00
IUUC-Mmu-064266	Mus musculus	89.87	0.00e+00	727.00
IUUC-Mpu-065766	Mustela putorius furo	99.34	0.00e+00	625.00
IUUC-Mlu-067221	Myotis lucifugus	88.92	0.00e+00	718.00
IUUC-Nle-069515	Nomascus leucogenys	99.68	0.00e+00	658.00
IUUC-Opr-070195	Ochotona princeps	81.68	0.00e+00	638.00
IUUC-Ont-071535	Oreochromis niloticus	72.15	2.00e-163	568.00
IUUC-Oan-072899	Ornithorhynchus anatinus	97.84	6.00e-107	379.00
IUUC-Ocu-074666	Oryctolagus cuniculus	99.67	0.00e+00	626.00
IUUC-Ola-086578	Oryzias latipes	94.62	0.00e+00	637.00
IUUC-Oga-089090	Otolemur garnettii	89.42	0.00e+00	721.00
IUUC-Oar-090017	Ovis aries	88.83	0.00e+00	710.00
IUUC-Pan-092198	Papio anubis	99.68	0.00e+00	658.00
IUUC-Psi-093030	Pelodiscus sinensis	83.08	0.00e+00	689.00
IUUC-Pma-094140	Petromyzon marinus	69.48	3.00e-82	297.00
IUUC-Pfo-097182	Poecilia formosa	94.32	0.00e+00	639.00
IUUC-Pab-098157	Pongo abelii	99.68	0.00e+00	665.00
IUUC-Pca-100988	Procavia capensis	68.86	5.00e-145	506.00
IUUC-Pva-102232	Pteropus vampyrus	100.00	6.00e-161	559.00
IUUC-Rno-105526	Rattus norvegicus	95.30	1.00e-180	625.00
IUUC-Sha-106754	Sarcophilus harrisii	88.35	0.00e+00	716.00
IUUC-Ssc-115390	Sus scrofa	89.65	0.00e+00	723.00
IUUC-Tgu-117377	Taeniopygia guttata	86.01	0.00e+00	685.00
IUUC-Tru-117938	Takifugu rubripes	94.32	0.00e+00	638.00
IUUC-Tsy-119392	Tarsius syrichta	79.13	1.00e-174	605.00
IUUC-Tni-119834	Tetraodon nigroviridis	66.33	1.00e-154	538.00
IUUC-Tbe-127469	Tupaia belangeri	86.97	0.00e+00	647.00
IUUC-Ttr-128252	Tursiops truncatus	86.87	0.00e+00	692.00
IUUC-Vpa-130173	Vicugna pacos	80.95	6.00e-155	540.00
IUUC-Xtr-131803	Xenopus tropicalis	83.04	0.00e+00	681.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence