iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	9.00e-06	25.9	309	384

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 1    vqvtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL..eddktLady.glkdgstihllek 72
           ++++v sl+++  l++ +++++t a++ e ++k+++i +  q Liy+G+ L  e ++  +++ + ++++ i+++ +
   Q: 309  MVIHVFSLQHMtALKIYIHSYNTAAVFHELVYKQTKIISSNQELIYEGRRLvlELGRLAQHFpKTTEENPIFVTSR 384
           6899**********************************************98899999999999999999998866 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MQSTSNHLWL LSDILGQGAT ANVFRGRHKK TGDLYAVKVF NNISFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTTR HKVLIMEFCP CGSLYTVLEE PSNAYGLPES EFLIVLRDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCGGGAGC CGCGGGCTGT ACGCGGCGGA CGCTCGCTGG GTAAGAGGGG CGGGCGGAGG 60
CCGGTGGGAG CGGACAGGGA TGGAGGGGAC GGGCGGGGGC GCGCCCGGAG GGTCGGGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0045087--P:innate immune response
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

KEGG

rno:299827

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	94.38	0.00e+00	1451.00
IUUC-Apl-004028	Anas platyrhynchos	85.60	0.00e+00	1333.00
IUUC-Aca-004998	Anolis carolinensis	81.48	0.00e+00	1269.00
IUUC-Ame-011617	Astyanax mexicanus	70.34	0.00e+00	1053.00
IUUC-Bta-012799	Bos taurus	93.83	0.00e+00	1447.00
IUUC-Cja-019357	Callithrix jacchus	94.11	0.00e+00	1449.00
IUUC-Cfa-020309	Canis familiaris	93.55	0.00e+00	1442.00
IUUC-Cpo-022062	Cavia porcellus	93.00	0.00e+00	1429.00
IUUC-Csa-023517	Chlorocebus sabaeus	94.38	0.00e+00	1458.00
IUUC-Cho-025037	Choloepus hoffmanni	91.52	0.00e+00	952.00
IUUC-Cin-025580	Ciona intestinalis	40.32	2.00e-149	523.00
IUUC-Csv-025818	Ciona savignyi	39.05	3.00e-141	495.00
IUUC-Dre-027527	Danio rerio	71.11	0.00e+00	1074.00
IUUC-Dno-029475	Dasypus novemcinctus	82.32	0.00e+00	1099.00
IUUC-Dme-031698	Drosophila melanogaster	39.78	1.00e-134	473.00
IUUC-Ete-033090	Echinops telfairi	80.66	0.00e+00	1199.00
IUUC-Eca-033996	Equus caballus	92.04	0.00e+00	1428.00
IUUC-Eeu-035082	Erinaceus europaeus	85.36	0.00e+00	845.00
IUUC-Fca-035921	Felis catus	90.98	0.00e+00	1390.00
IUUC-Fal-037406	Ficedula albicollis	85.60	0.00e+00	1339.00
IUUC-Gmo-038721	Gadus morhua	70.39	0.00e+00	1035.00
IUUC-Gga-041234	Gallus gallus	85.05	0.00e+00	1333.00
IUUC-Gac-042315	Gasterosteus aculeatus	71.17	0.00e+00	1055.00
IUUC-Ggo-044885	Gorilla gorilla	88.48	0.00e+00	1344.00
IUUC-Hsa-046847	Homo sapiens	94.51	0.00e+00	1457.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	92.93	0.00e+00	1431.00
IUUC-Lch-049731	Latimeria chalumnae	54.48	0.00e+00	771.00
IUUC-Loc-051879	Lepisosteus oculatus	72.66	0.00e+00	1092.00
IUUC-Laf-054232	Loxodonta africana	92.33	0.00e+00	1426.00
IUUC-Mcc-055447	Macaca mulatta	94.51	0.00e+00	1460.00
IUUC-Meu-056138	Macropus eugenii	94.86	0.00e+00	672.00
IUUC-Mga-059460	Meleagris gallopavo	83.86	0.00e+00	1305.00
IUUC-Mmr-061445	Microcebus murinus	94.51	0.00e+00	1451.00
IUUC-Mmu-064107	Mus musculus	97.53	0.00e+00	1465.00
IUUC-Mpu-066834	Mustela putorius furo	94.51	0.00e+00	1454.00
IUUC-Mlu-068006	Myotis lucifugus	91.37	0.00e+00	1384.00
IUUC-Nle-069280	Nomascus leucogenys	94.10	0.00e+00	1456.00
IUUC-Opr-070728	Ochotona princeps	86.52	0.00e+00	1172.00
IUUC-Ont-071621	Oreochromis niloticus	72.47	0.00e+00	1078.00
IUUC-Oan-073162	Ornithorhynchus anatinus	89.57	0.00e+00	1340.00
IUUC-Ocu-074787	Oryctolagus cuniculus	94.25	0.00e+00	1451.00
IUUC-Ola-086737	Oryzias latipes	33.04	1.00e-27	118.00
IUUC-Oga-088764	Otolemur garnettii	93.55	0.00e+00	1440.00
IUUC-Oar-090333	Ovis aries	93.56	0.00e+00	1441.00
IUUC-Ptr-090568	Pan troglodytes	94.24	0.00e+00	1454.00
IUUC-Pan-091979	Papio anubis	94.25	0.00e+00	1450.00
IUUC-Psi-093336	Pelodiscus sinensis	85.60	0.00e+00	1321.00
IUUC-Pma-094200	Petromyzon marinus	43.51	4.00e-173	601.00
IUUC-Pfo-096354	Poecilia formosa	71.41	0.00e+00	1068.00
IUUC-Pab-098499	Pongo abelii	94.38	0.00e+00	1457.00
IUUC-Pva-102454	Pteropus vampyrus	92.59	0.00e+00	1408.00
IUUC-Sha-106864	Sarcophilus harrisii	91.12	0.00e+00	1415.00
IUUC-Sar-113728	Sorex araneus	85.57	0.00e+00	1232.00
IUUC-Tgu-117200	Taeniopygia guttata	84.15	0.00e+00	1318.00
IUUC-Tsy-119017	Tarsius syrichta	93.75	0.00e+00	1073.00
IUUC-Tni-120724	Tetraodon nigroviridis	70.39	0.00e+00	1060.00
IUUC-Tbe-127887	Tupaia belangeri	84.30	0.00e+00	1014.00
IUUC-Ttr-129111	Tursiops truncatus	86.42	0.00e+00	1306.00
IUUC-Vpa-130724	Vicugna pacos	94.38	0.00e+00	1451.00
IUUC-Xtr-132091	Xenopus tropicalis	75.24	0.00e+00	1168.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence