iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.3__1753__AT3G15980.3	fgenesh2_kg.3__1753__AT3G15980.3	fgenesh2_kg.3__1753__AT3G15980.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.10e-35	118.7	184	224
UBD/Beta-Prp	3.10e-68	230.8	11	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvllks 38
           H+ +v+c+++    d ++l++GsdD+t kvWD+ t  ++++
   Q: 184  HQKGVNCVDYftgGDkPYLITGSDDHTAKVWDYQTKSCVQT 224
           999*****966*9778*******************999986 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdls 82
           ++++++++++v+ +p +++++++ + gt+ +w+++t++  +s++  + +v++ kf+p++++ v g++D++i+v++++
   Q: 11   FAQRSERVKSVDLHPTEPWILASLYAGTVCIWNYQTQTITKSFEVTDLPVRSAKFIPRKQWVVAGADDMHIRVYNYN 87
           66788899********************************************************************* PP
   S: 83   tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslD 158
           t + v+++++h+d++++++++p+  +++s s+d  i++wd+e+g+   ++++gh++ v+ vv++p++ n ++s+slD
   Q: 88   TMDKVRVFEAHSDYIRCVAVHPTLPYVLSSSDDMLIKLWDWENGWACTQIFEGHSHYVMQVVFNPKDtNTFASASLD 164
           *********************************************9999**************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvysls..fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspn 233
           rt+++W+l + +   tl   h++ v++++     ++++l++gs+d t k+wd+qt++cv+tl ght nv+ v f+p+
   Q: 165  RTIKIWNLGSPDPNFTLDA-HQKGVNCVDyfTGGDKPYLITGSDDHTAKVWDYQTKSCVQTLDGHTHNVSAVCFHPE 240
           *****************98.*********6444555***************************************** PP
   S: 234  derlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvl 282
             ++++gs+Dg++riW  ++  l +tl++  ++v+++ +++ +++v++ 
   Q: 241  LPIIITGSEDGTVRIWHATTYRLENTLNYGLERVWAIGYIKSSRRVVIG 289
           *************************************997777777654 PP

Organism

Arabidopsis lyrata

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

Protein Sequence
(Fasta)

MPLRLDIKRK FAQRSERVKS VDLHPTEPWI LASLYAGTVC IWNYQTQTIT KSFEVTDLPV 60
RSAKFIPRKQ WVVAGADDMH IRVYNYNTMD KVRVFEAHSD YIRCVAVHPT LPYVLSSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCTCCGCCG TATTAATACA AGCTCTCTGA ACGCACTCTA CGACGAGCCT AACGTCTTTC 60
TCCGATCGCC GGTTAGCAGA TTCAAGCGAA ATACGAGATC CGACGAGCAG ATCTTCTGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030663--C:COPI-coated vesicle membrane
GO:0000139--C:Golgi membrane
GO:0030117--C:membrane coat
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

KEGG

aly:ARALYDRAFT_479052

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ath-006670	Arabidopsis thaliana	95.38	0.00e+00	1710.00
IUUC-Bol-016338	Brassica oleracea	95.78	0.00e+00	1689.00
IUUC-Bra-017576	Brassica rapa	91.47	0.00e+00	1706.00
IUUC-Cel-018387	Caenorhabditis elegans	55.21	0.00e+00	990.00
IUUC-Dme-031791	Drosophila melanogaster	57.35	0.00e+00	1005.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence