iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025193

UUCD1 version

UUC-CiI-00468

Ensembl Protein ID

ENSCINP00000029993.1

UniProt Accession

H2XK11; H2XK11_CIOIN

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000023863.1	ENSCINT00000032352.1	ENSCINP00000029993.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.10e-64	217.8	1	265

Active Site

Position(s)	Description	Evidence
234	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 70   lFeflGrllgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeee..L 156
           +F+f+G+l+g+a++++++ldl+l++ ++kll g ++sl+d+e+ d+ +++ l  +k+ + + ++e++++  +  ++ + ++ + +    
   Q: 1    MFKFFGILIGVAIRTKKPLDLHLAPIVWKLLAGISVSLQDVEDSDEMFVQMLHALKNIDVAGVDESNFNEIIPLESFKAQSWNGKFvpV 89
           7*********************************************************9888888888888777666655444443338 PP
   S: 157  kpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspa 245
           + gG+ ip t  N++eY ++ + +rl+e  ++qve +r G++ +ipl l++l t+  le+l+cG+++id++ lk + +y++ + eds+ 
   Q: 90   VVGGDGIPLTFRNRKEYSDQALYFRLHE-LDQQVEWVRMGISHIIPLPLFTLMTQTRLEQLVCGMPDIDISVLKTNMRYRD-VAEDSEL 176
           9***************************.**************************************************88.******* PP
   S: 246  iqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgF 333
           i+w+w++lee++++er  fL+Fv+g+srlP+  ++ + p++f++ k d+  d+lP+s+TCf++L+LP++ss+ ++ e+L+yAi++++++
   Q: 177  IHWLWQTLEELNRDERVLFLKFVSGRSRLPVHPVD-M-PQRFQVMKiDRPIDSLPTSQTCFFQLRLPPFSSQAVMAERLRYAIRHCRSI 263
           ******************************95554.3.5789999977777***********************************999 PP
   S: 334  el 335
           ++
   Q: 264  DM 265
           87 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

MFKFFGILIG VAIRTKKPLD LHLAPIVWKL LAGISVSLQD VEDSDEMFVQ MLHALKNIDV 60
AGVDESNFNE IIPLESFKAQ SWNGKFVPVV VGGDGIPLTF RNRKEYSDQA LYFRLHELDQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTGATGATA CAATCACTGA AATATGCCAG GTTTGAGACT AATGTTAGTT CTCTGACAAA 60
TTCTTGCCAG ATGGCAGATA AAACATCGGA AATATATATC AATACGCTAC GTTTGTACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-010860	Astyanax mexicanus	62.04	3.00e-102	363.00
IUUC-Cho-024567	Choloepus hoffmanni	60.28	2.00e-97	351.00
IUUC-Csv-026125	Ciona savignyi	77.58	1.00e-92	330.00
IUUC-Eeu-034702	Erinaceus europaeus	56.21	7.00e-49	190.00
IUUC-Meu-056521	Macropus eugenii	62.80	3.00e-76	281.00
IUUC-Tsy-119647	Tarsius syrichta	52.80	2.00e-60	228.00
IUUC-Tbe-127346	Tupaia belangeri	61.21	4.00e-101	363.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence