iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074151

UUCD1 version

UUC-OrC-00831

Ensembl Protein ID

ENSOCUP00000022844.2

UniProt Accession

G1U0G4; G1U0G4_RABIT

Protein Name

Uncharacterized protein

Gene Name

CRBN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000025795.2	ENSOCUT00000030486.2	ENSOCUP00000022844.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	97.26	0.00e+00	819.00	IUUC-Hsa-046888

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDSWRPLDRL SQAGADGEDE SEDEDEMEVE DQDSKEAKKP NIINFDTSLP TSHTYLGADM 60
EEFHGRTLHD DDSCPVIPVL PQVVMILIPG QTLPLQLSHP PEVSMVRSLI QKDRTFAVLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACAAGGTT TAATCCGAGA AAGCTGTTTG CCTAGATGTT TTAGTCGGGT GAGTTCCCGT 60
TGTCATGGAC AGCTGGAGGC CCCTGGACAG GCTGAGCCAA GCGGGAGCCG ATGGTGAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR034750--CULT
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR004910--Yippee/Mis18/Cereblon

PROSITE

PS51788--CULT
PS51787--LON_N

Pfam

PF02190--LON_substr_bdg
PF03226--Yippee-Mis18

SMART

SM00464--LON

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0046872--F:metal ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000549	Aegilops tauschii	29.95	1.00e-23	104.00
IUUC-Aml-002159	Ailuropoda melanoleuca	95.29	0.00e+00	800.00
IUUC-Atr-002820	Amborella trichopoda	38.25	5.00e-37	149.00
IUUC-Apl-003508	Anas platyrhynchos	84.65	0.00e+00	726.00
IUUC-Aca-004675	Anolis carolinensis	83.70	0.00e+00	718.00
IUUC-Aly-005404	Arabidopsis lyrata	36.32	1.00e-37	150.00
IUUC-Ath-006819	Arabidopsis thaliana	35.79	3.00e-37	149.00
IUUC-Ani-009423	Aspergillus nidulans	38.60	4.60e-02	32.70
IUUC-Ame-010773	Astyanax mexicanus	69.75	7.00e-168	583.00
IUUC-Bta-012711	Bos taurus	94.53	0.00e+00	803.00
IUUC-Bdi-014416	Brachypodium distachyon	28.38	7.00e-44	171.00
IUUC-Bol-015668	Brassica oleracea	36.73	4.00e-39	155.00
IUUC-Bra-016836	Brassica rapa	36.15	3.00e-39	156.00
IUUC-Cja-019624	Callithrix jacchus	97.26	0.00e+00	822.00
IUUC-Cpo-022319	Cavia porcellus	94.78	0.00e+00	798.00
IUUC-Csa-023791	Chlorocebus sabaeus	97.01	0.00e+00	818.00
IUUC-Cho-024850	Choloepus hoffmanni	96.53	0.00e+00	692.00
IUUC-Csv-025832	Ciona savignyi	44.02	3.00e-88	318.00
IUUC-Cgl-026484	Colletotrichum gloeosporioides	31.82	2.80e-01	30.00
IUUC-Dre-028071	Danio rerio	70.72	6.00e-171	593.00
IUUC-Dno-029431	Dasypus novemcinctus	96.52	0.00e+00	810.00
IUUC-Dor-030571	Dipodomys ordii	79.35	0.00e+00	649.00
IUUC-Dme-031920	Drosophila melanogaster	27.96	6.00e-36	145.00
IUUC-Eca-033462	Equus caballus	95.27	0.00e+00	805.00
IUUC-Fca-036279	Felis catus	94.62	0.00e+00	812.00
IUUC-Fal-037498	Ficedula albicollis	80.90	0.00e+00	692.00
IUUC-Fox-037856	Fusarium oxysporum	42.86	2.40e-01	30.40
IUUC-Gmo-038734	Gadus morhua	74.55	5.00e-175	607.00
IUUC-Gga-040615	Gallus gallus	85.82	0.00e+00	732.00
IUUC-Gac-041426	Gasterosteus aculeatus	73.05	2.00e-176	612.00
IUUC-Gma-043891	Glycine max	36.19	4.00e-39	155.00
IUUC-Ggo-045108	Gorilla gorilla	97.01	0.00e+00	818.00
IUUC-Hsa-046888	Homo sapiens	97.26	0.00e+00	819.00
IUUC-Itr-047937	Ictidomys tridecemlineatus	95.52	0.00e+00	803.00
IUUC-Lch-050189	Latimeria chalumnae	76.00	9.00e-174	602.00
IUUC-Lpe-050808	Leersia perrieri	41.53	1.00e-41	164.00
IUUC-Loc-051762	Lepisosteus oculatus	76.11	0.00e+00	643.00
IUUC-Laf-053882	Loxodonta africana	95.74	0.00e+00	797.00
IUUC-Mcc-054883	Macaca mulatta	97.01	0.00e+00	818.00
IUUC-Mtr-058216	Medicago truncatula	37.33	2.00e-40	159.00
IUUC-Mdo-062260	Monodelphis domestica	89.45	0.00e+00	752.00
IUUC-Mmu-063438	Mus musculus	94.53	0.00e+00	801.00
IUUC-Mac-064610	Musa acuminata	44.39	1.00e-45	178.00
IUUC-Mpu-066362	Mustela putorius furo	95.27	0.00e+00	806.00
IUUC-Nle-069908	Nomascus leucogenys	97.26	0.00e+00	819.00
IUUC-Ont-072223	Oreochromis niloticus	75.00	2.00e-179	622.00
IUUC-Oba-075882	Oryza barthii	40.59	8.00e-42	164.00
IUUC-Obr-076670	Oryza brachyantha	38.61	7.00e-40	158.00
IUUC-Ogl-077753	Oryza glaberrima	40.59	8.00e-42	164.00
IUUC-Ogu-078786	Oryza glumaepatula	40.38	1.00e-41	164.00
IUUC-Oin-079191	Oryza indica	40.59	8.00e-42	164.00
IUUC-Olo-080357	Oryza longistaminata	40.59	8.00e-42	164.00
IUUC-Ome-081227	Oryza meridionalis	30.32	2.00e-18	87.40
IUUC-Oni-082557	Oryza nivara	40.59	8.00e-42	164.00
IUUC-Opu-083920	Oryza punctata	40.59	4.00e-41	162.00
IUUC-Oru-085227	Oryza rufipogon	40.59	8.00e-42	164.00
IUUC-Ola-087321	Oryzias latipes	71.14	9.00e-171	592.00
IUUC-Oga-088413	Otolemur garnettii	95.52	0.00e+00	806.00
IUUC-Oar-089512	Ovis aries	94.09	0.00e+00	801.00
IUUC-Ptr-090764	Pan troglodytes	97.26	0.00e+00	819.00
IUUC-Pan-091942	Papio anubis	97.01	0.00e+00	818.00
IUUC-Psi-092985	Pelodiscus sinensis	85.82	0.00e+00	725.00
IUUC-Ppa-095670	Physcomitrella patens	41.45	1.00e-45	177.00
IUUC-Pfo-097251	Poecilia formosa	74.56	0.00e+00	626.00
IUUC-Pab-097842	Pongo abelii	97.26	0.00e+00	818.00
IUUC-Pop-099118	Populus trichocarpa	37.67	9.00e-43	167.00
IUUC-Pca-101077	Procavia capensis	83.33	0.00e+00	679.00
IUUC-Ppe-101706	Prunus persica	37.86	4.00e-41	162.00
IUUC-Pva-102245	Pteropus vampyrus	80.51	1.00e-145	508.00
IUUC-Rno-105788	Rattus norvegicus	94.53	0.00e+00	801.00
IUUC-Smo-109165	Selaginella moellendorffii	42.03	2.00e-46	180.00
IUUC-Sit-109818	Setaria italica	40.50	3.00e-42	166.00
IUUC-Sly-111062	Solanum lycopersicum	38.58	9.00e-44	171.00
IUUC-Sbi-114298	Sorghum bicolor	38.86	3.00e-43	169.00
IUUC-Ssc-115779	Sus scrofa	96.53	0.00e+00	698.00
IUUC-Tgu-117378	Taeniopygia guttata	81.34	0.00e+00	703.00
IUUC-Tru-118515	Takifugu rubripes	73.35	1.00e-166	578.00
IUUC-Tsy-119555	Tarsius syrichta	93.70	0.00e+00	733.00
IUUC-Tni-119679	Tetraodon nigroviridis	74.30	4.00e-166	577.00
IUUC-Tca-121374	Theobroma cacao	37.64	2.00e-32	133.00
IUUC-Tae-123098	Triticum aestivum	33.09	3.00e-52	199.00
IUUC-Tur-126689	Triticum urartu	29.41	7.00e-16	78.60
IUUC-Vpa-130719	Vicugna pacos	83.04	0.00e+00	691.00
IUUC-Vvi-131014	Vitis vinifera	40.33	2.00e-40	160.00
IUUC-Xtr-131811	Xenopus tropicalis	74.50	0.00e+00	631.00
IUUC-Xma-133238	Xiphophorus maculatus	75.26	0.00e+00	627.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence