iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054090

Ensembl Protein ID

ENSLAFP00000008060.3

UniProt Accession

G3T420; G3T420_LOXAF

Protein Name

Uncharacterized protein

Gene Name

FXN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000009606.3	ENSLAFT00000009606.3	ENSLAFP00000008060.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Other/Other	76.78	4.00e-85	311.00	IUUC-Hsa-046921

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MWTLGRRAAA GFLPRAAPPG LTQARAGAPG PPEGALLCGR RGLQCARPSC EYRHHSSNPY 60
CLNQILNAKK QSVHLMNLRK TGTLGDPSSL NETTYERLAE ETLDSLAEFF EDLADKPYTF 120

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Nucleotide Sequence
(Fasta)

ATGTGGACGC TCGGGCGCCG CGCGGCCGCC GGCTTCCTGC CCCGGGCGGC GCCCCCGGGC 60
CTGACCCAGG CCCGCGCCGG GGCCCCCGGG CCGCCGGAAG GCGCCTTGCT CTGCGGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR017789--Frataxin
IPR002908--Frataxin/CyaY
IPR020895--Frataxin_CS

PROSITE

PS01344--FRATAXIN_1
PS50810--FRATAXIN_2

Pfam

PF01491--Frataxin_Cyay

PRINTS

PR00904--FRATAXIN

SMART

SM01219--Frataxin_Cyay

Gene Ontology

GO:0005829--C:cytosol
GO:0005739--C:mitochondrion
GO:0051537--F:2 iron, 2 sulfur cluster binding
GO:0008199--F:ferric iron binding
GO:0008198--F:ferrous iron binding
GO:0004322--F:ferroxidase activity
GO:0034986--F:iron chaperone activity
GO:0007628--P:adult walking behavior
GO:0009060--P:aerobic respiration
GO:0006879--P:cellular iron ion homeostasis
GO:0070301--P:cellular response to hydrogen peroxide
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0018283--P:iron incorporation into metallo-sulfur cluster
GO:0007005--P:mitochondrion organization
GO:0040015--P:negative regulation of multicellular organism growth
GO:0046621--P:negative regulation of organ growth
GO:0090201--P:negative regulation of release of cytochrome c from mitochondria
GO:0006119--P:oxidative phosphorylation
GO:1904234--P:positive regulation of aconitate hydratase activity
GO:0030307--P:positive regulation of cell growth
GO:0008284--P:positive regulation of cell proliferation
GO:1904231--P:positive regulation of succinate dehydrogenase activity
GO:0019230--P:proprioception
GO:0016540--P:protein autoprocessing
GO:0010722--P:regulation of ferrochelatase activity
GO:0010039--P:response to iron ion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002122	Ailuropoda melanoleuca	73.53	8.00e-82	296.00
IUUC-Apl-003853	Anas platyrhynchos	82.64	2.00e-56	210.00
IUUC-Aca-005026	Anolis carolinensis	72.79	8.00e-61	225.00
IUUC-Aly-006200	Arabidopsis lyrata	48.89	8.00e-20	89.70
IUUC-Ath-007033	Arabidopsis thaliana	48.89	7.00e-20	90.10
IUUC-Ago-007707	Ashbya gossypii	46.36	1.00e-19	87.80
IUUC-Acl-008146	Aspergillus clavatus	38.52	2.00e-18	85.50
IUUC-Afl-008501	Aspergillus flavus	39.29	2.00e-15	75.10
IUUC-Afu-008851	Aspergillus fumigatus	34.88	5.00e-19	87.40
IUUC-Ani-009129	Aspergillus nidulans	40.00	1.00e-11	63.20
IUUC-Ang-009557	Aspergillus niger	37.80	1.00e-17	82.80
IUUC-Ate-010486	Aspergillus terreus	38.58	3.00e-18	84.70
IUUC-Bgr-012108	Blumeria graminis	41.03	2.00e-15	75.10
IUUC-Bta-013437	Bos taurus	73.68	2.00e-79	287.00
IUUC-Bci-013810	Botrytis cinerea	48.31	5.00e-15	74.30
IUUC-Bdi-014226	Brachypodium distachyon	47.41	7.00e-25	106.00
IUUC-Bol-015092	Brassica oleracea	48.89	3.00e-20	91.30
IUUC-Bra-017945	Brassica rapa	48.89	7.00e-20	89.40
IUUC-Cel-018466	Caenorhabditis elegans	50.46	1.00e-25	108.00
IUUC-Cja-019306	Callithrix jacchus	76.30	3.00e-79	287.00
IUUC-Cfa-020063	Canis familiaris	74.16	6.00e-78	283.00
IUUC-Cpo-021325	Cavia porcellus	72.60	2.00e-82	297.00
IUUC-Cre-022889	Chlamydomonas reinhardtii	49.55	6.00e-22	97.10
IUUC-Csa-023739	Chlorocebus sabaeus	77.14	2.00e-88	317.00
IUUC-Cho-024324	Choloepus hoffmanni	78.95	4.00e-81	293.00
IUUC-Cgl-026402	Colletotrichum gloeosporioides	43.22	6.00e-19	87.00
IUUC-Cne-027094	Cryptococcus neoformans	40.74	2.00e-13	68.90
IUUC-Cme-027112	Cyanidioschyzon merolae	47.25	2.00e-13	67.80
IUUC-Dre-028813	Danio rerio	58.28	3.00e-46	177.00
IUUC-Dno-029949	Dasypus novemcinctus	85.07	7.00e-55	205.00
IUUC-Dse-031482	Dothistroma septosporum	42.74	2.00e-19	89.00
IUUC-Dme-031608	Drosophila melanogaster	51.22	2.00e-32	131.00
IUUC-Ete-032937	Echinops telfairi	100.00	2.00e-13	67.80
IUUC-Eca-033899	Equus caballus	87.58	2.00e-64	237.00
IUUC-Fca-036579	Felis catus	76.57	6.00e-63	233.00
IUUC-Fox-037940	Fusarium oxysporum	49.14	4.00e-23	100.00
IUUC-Fso-038465	Fusarium solani	50.86	2.00e-23	101.00
IUUC-Ggr-040089	Gaeumannomyces graminis	46.49	1.00e-20	93.20
IUUC-Gga-040910	Gallus gallus	80.00	9.00e-64	235.00
IUUC-Gma-044349	Glycine max	46.28	1.00e-24	105.00
IUUC-Ggo-044854	Gorilla gorilla	78.57	4.00e-78	283.00
IUUC-Hsa-046921	Homo sapiens	78.10	2.00e-77	281.00
IUUC-Hvu-047142	Hordeum vulgare	45.61	1.00e-24	105.00
IUUC-Kpa-049187	Komagataella pastoris	34.76	2.00e-15	74.70
IUUC-Lch-050614	Latimeria chalumnae	68.84	1.00e-54	205.00
IUUC-Lpe-051184	Leersia perrieri	37.58	3.00e-24	104.00
IUUC-Loc-052083	Lepisosteus oculatus	71.43	6.00e-48	182.00
IUUC-Lma-053209	Leptosphaeria maculans	40.18	7.00e-15	73.20
IUUC-Meu-056814	Macropus eugenii	80.00	2.00e-67	247.00
IUUC-Mor-057169	Magnaporthe oryzae	46.34	1.00e-21	95.90
IUUC-Mpo-057483	Magnaporthe poae	46.09	2.00e-21	95.50
IUUC-Mtr-058166	Medicago truncatula	48.60	8.00e-20	89.70
IUUC-Mla-059015	Melampsora laricipopulina	46.30	1.00e-19	88.60
IUUC-Mvi-060356	Microbotryum violaceum	51.09	1.00e-19	89.70
IUUC-Mdo-062658	Monodelphis domestica	65.46	2.00e-66	244.00
IUUC-Mmu-063470	Mus musculus	72.12	3.00e-80	290.00
IUUC-Mac-065327	Musa acuminata	53.70	7.00e-26	110.00
IUUC-Mpu-065761	Mustela putorius furo	80.95	6.00e-66	242.00
IUUC-Mlu-067175	Myotis lucifugus	71.98	7.00e-78	282.00
IUUC-Nfi-068535	Neosartorya fischeri	35.63	3.00e-19	88.60
IUUC-Ncr-068966	Neurospora crassa	43.31	2.00e-22	99.00
IUUC-Opr-070533	Ochotona princeps	53.38	8.00e-31	125.00
IUUC-Oan-073024	Ornithorhynchus anatinus	80.00	3.00e-59	221.00
IUUC-Ocu-074451	Oryctolagus cuniculus	70.75	1.00e-68	253.00
IUUC-Oba-075540	Oryza barthii	44.83	2.00e-23	102.00
IUUC-Obr-076285	Oryza brachyantha	44.83	4.00e-24	104.00
IUUC-Ogl-077827	Oryza glaberrima	44.83	2.00e-23	102.00
IUUC-Ogu-078491	Oryza glumaepatula	44.83	1.00e-23	102.00
IUUC-Oin-080149	Oryza indica	44.83	2.00e-23	102.00
IUUC-Olo-080318	Oryza longistaminata	42.62	1.00e-21	94.70
IUUC-Oni-083037	Oryza nivara	44.83	2.00e-23	102.00
IUUC-Opu-083448	Oryza punctata	44.83	1.00e-23	102.00
IUUC-Oru-084793	Oryza rufipogon	44.83	2.00e-23	102.00
IUUC-Osa-086032	Oryza sativa	44.83	2.00e-23	102.00
IUUC-Ola-086956	Oryzias latipes	65.62	4.00e-45	173.00
IUUC-Olu-087806	Ostreococcus lucimarinus	40.91	6.00e-17	79.70
IUUC-Oga-089029	Otolemur garnettii	79.43	2.00e-85	308.00
IUUC-Oar-089471	Ovis aries	71.29	2.00e-76	278.00
IUUC-Pan-092091	Papio anubis	77.62	7.00e-89	319.00
IUUC-Psi-093193	Pelodiscus sinensis	77.55	4.00e-66	243.00
IUUC-Pma-094540	Petromyzon marinus	63.03	2.00e-42	163.00
IUUC-Pno-094873	Phaeosphaeria nodorum	37.60	3.00e-16	78.20
IUUC-Ppa-095343	Physcomitrella patens	45.45	5.00e-18	84.30
IUUC-Pfo-097093	Poecilia formosa	67.52	3.00e-44	171.00
IUUC-Pab-098781	Pongo abelii	91.25	2.00e-28	117.00
IUUC-Pop-098983	Populus trichocarpa	41.79	7.00e-23	100.00
IUUC-Pca-100872	Procavia capensis	75.12	3.00e-69	254.00
IUUC-Ppe-101711	Prunus persica	51.11	1.00e-20	92.80
IUUC-Pva-102256	Pteropus vampyrus	73.21	4.00e-84	303.00
IUUC-Pgr-103607	Puccinia graminis	44.26	3.00e-21	94.70
IUUC-Pte-104220	Pyrenophora teres	36.97	1.00e-14	72.00
IUUC-Pyt-104562	Pyrenophora triticirepentis	36.97	3.00e-15	74.70
IUUC-Rno-105021	Rattus norvegicus	67.79	7.00e-76	276.00
IUUC-Sce-106182	Saccharomyces cerevisiae	49.30	1.00e-15	75.50
IUUC-Sha-107279	Sarcophilus harrisii	83.45	8.00e-69	252.00
IUUC-Sja-107819	Schizosaccharomyces japonicus	42.86	3.00e-20	90.90
IUUC-Spo-108197	Schizosaccharomyces pombe	47.17	1.00e-20	91.70
IUUC-Smo-108810	Selaginella moellendorffii	53.57	3.00e-21	93.20
IUUC-Sit-110256	Setaria italica	45.54	1.00e-23	102.00
IUUC-Sly-111448	Solanum lycopersicum	45.69	9.00e-23	99.80
IUUC-Stu-112702	Solanum tuberosum	45.69	6.00e-23	100.00
IUUC-Sbi-113956	Sorghum bicolor	46.96	2.00e-25	108.00
IUUC-Sre-115024	Sporisorium reilianum	37.50	1.00e-16	79.30
IUUC-Ssc-116034	Sus scrofa	77.51	8.00e-86	309.00
IUUC-Tgu-117503	Taeniopygia guttata	76.06	6.00e-56	209.00
IUUC-Tsy-119166	Tarsius syrichta	64.71	1.00e-43	168.00
IUUC-Tni-120703	Tetraodon nigroviridis	43.38	1.00e-25	109.00
IUUC-Tca-121473	Theobroma cacao	51.11	3.00e-20	91.30
IUUC-Tre-122241	Trichoderma reesei	43.75	3.00e-20	90.50
IUUC-Tvi-122347	Trichoderma virens	41.41	1.00e-18	85.50
IUUC-Tae-124560	Triticum aestivum	46.15	1.00e-23	102.00
IUUC-Tur-126452	Triticum urartu	35.33	9.00e-26	109.00
IUUC-Tme-127205	Tuber melanosporum	48.96	1.00e-18	84.30
IUUC-Ttr-128186	Tursiops truncatus	75.12	9.00e-74	269.00
IUUC-Uma-129523	Ustilago maydis	36.76	3.00e-16	78.20
IUUC-Vda-129793	Verticillium dahliae	43.97	1.00e-19	89.40
IUUC-Vpa-130040	Vicugna pacos	85.81	9.00e-72	261.00
IUUC-Vvi-131588	Vitis vinifera	50.00	2.00e-20	92.00
IUUC-Yli-134631	Yarrowia lipolytica	49.41	1.00e-17	82.40
IUUC-Zma-135478	Zea mays	35.61	4.00e-27	114.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence