iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Itr-048240

Ensembl Protein ID

ENSSTOP00000005174.2

UniProt Accession

I3M6N8; I3M6N8_ICTTR

Genbank Protein ID

ENSSTOP00000005174

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

AGTP01010405

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000005756.2	ENSSTOT00000005786.2	ENSSTOP00000005174.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.80e-11	41.6	113	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++v++lydy+a+ +deL++ +G  ++ +   ++ +gW+kg    +  +  fP+n+ve ++
   Q: 113  RTVKALYDYKAKRSDELSFCRGALIHNV--SKEPGGWWKGD-YGTRIQQYFPSNYVEDIS 169
           789************************9..77889*****6.55556679******9985 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MRIPRDGAFL IRRRREGTDS YAITFRARGK VKHCRINRDG RHFVLGTSAY FESLVELVNY 60
YEKHALYRKM RLRYPVTPEL LERYNMERDI NSLYDVSRMY VDPSEINPSM PQRTVKALYD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGACTGCTG GGACGGGCCT GACGGGAAGC CCATCATCTA CCACGGCTGG ACGCGGACCA 60
CCAAGATCAA GTTTGACGAC GTCGTCCAGG CCATCAAAGA CCACGCCTTC GTTGCCTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR001192--PI-PLC_fam
IPR028381--PLC-gamma2
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0035556--P:intracellular signal transduction
GO:0016042--P:lipid catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Opr-070718	Ochotona princeps	93.36	0.00e+00	828.00
IUUC-Oga-088036	Otolemur garnettii	94.36	0.00e+00	1043.00
IUUC-Sre-115229	Sporisorium reilianum	43.33	1.00e-09	59.30
IUUC-Tsy-119139	Tarsius syrichta	97.24	3.00e-148	519.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence