iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tni-120553

Ensembl Protein ID

ENSTNIP00000006472.1

UniProt Accession

H3CDZ8; H3CDZ8_TETNG

Protein Name

Phosphoinositide phospholipase C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000003869.1	ENSTNIT00000006622.1	ENSTNIP00000006472.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.40e-12	45.4	801	859

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +k +v+++y+y+aq ddeL+++k  +++ +  ++q++gW+kg  +  gk+ l fP+n+ve+++
   Q: 801  FKCTVRAMYEYKAQRDDELSFTKNAIIYNV--DKQEGGWWKG--DCGGKKQLwFPANYVEEIS 859
           67789************************9..9*********..777777666*******986 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MAGTSGFFSN GPVTWMDNDA EMNNLYRDLE LGTVLTLFYS KKSQRPERRT FQVKLETRTI 60
IWTRGTDKIE GEIDIREIKE IRPGQKSRDF ERCLEDSAAR LDQAHCFVIL YGTEFRLKSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGGAA CCTCGGGCTT CTTTTCCAAC GGACCCGTAA CGTGGATGGA CAACGACGCC 60
GAGATGAACA ACCTGTACCG AGACCTGGAG CTAGGCACGG TGCTGACGCT GTTTTACTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS00018--EF_HAND_1
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00388--PI-PLC-X
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00148--PLCXc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0001525--P:angiogenesis
GO:0048844--P:artery morphogenesis
GO:0031101--P:fin regeneration
GO:0030851--P:granulocyte differentiation
GO:0060218--P:hematopoietic stem cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0016042--P:lipid catabolic process
GO:0035477--P:regulation of angioblast cell migration involved in selective angioblast sprouting
GO:0008016--P:regulation of heart contraction
GO:0001570--P:vasculogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Csa-024170	Chlorocebus sabaeus	77.59	0.00e+00	1454.00
IUUC-Opr-070718	Ochotona princeps	45.44	1.00e-159	557.00
IUUC-Ont-072524	Oreochromis niloticus	93.15	0.00e+00	1680.00
IUUC-Oan-073214	Ornithorhynchus anatinus	69.57	3.00e-37	147.00
IUUC-Ola-086820	Oryzias latipes	88.94	0.00e+00	1622.00
IUUC-Tru-117742	Takifugu rubripes	95.42	0.00e+00	1723.00
IUUC-Tsy-119139	Tarsius syrichta	45.76	1.00e-135	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence