iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Zma-134970

UUCD1 version

UUC-ZeM-01613

Ensembl Protein ID

Zm00001d022578_T001

UniProt Accession

A0A1D6IP61; A0A1D6IP61_MAIZE

Genbank Protein ID

ONM61042.1

Protein Name

Ubiquitin-activating enzyme E1 2

Genbank Nucleotide ID

CM007650

Gene Name

ZEAMMB73_Zm00001d022578

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Zm00001d022578	Zm00001d022578_T001	Zm00001d022578_T001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E1	5.40e-170	568.1	458	945

Active Site

Position(s)	Description	Evidence
639	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU10132}

Domain Profile

   S: 1    YDRQirlwGeeaqeklksakvllvGagglGcEllKnLvlaGv.....gsitvvDmdtvevsnlnrqFLfraedvgksKAevaaealkeln 85
           YD Qi ++G++ q+kl  a+v++vG g+lGcE+lKnL+l+Gv     g++t++D+d +e+snl+rqFLfr++++g+ K+ vaa+a+  +n
   Q: 458  YDAQISVFGSKLQKKLLDANVFIVGSGALGCEFLKNLALMGVscsskGKVTITDDDVIEKSNLSRQFLFRDWNIGQAKSTVAAAAAIAIN 547
           ****************************************************************************************** PP
   S: 86   pdvnveaheesiteleeeiv...FfkkfdvVvlaldnrearrkvnrlclnarvpliesgtlGllGqvrviikgltecyscsddppqktiP 172
           p+ +++a +++ ++++e+++   F + +dvV++aldn+ ar++++ +cl+ ++pl+esgtlG + +++ +i++lte y +s+dpp+k++P
   Q: 548  PSLQIDALQNRASPDTENVFhdtFWDGLDVVINALDNVNARMYMDMRCLYFQKPLLESGTLGAKCNTQMVIPHLTENYGASRDPPEKQAP 637
           ******************8899999999************************************************************** PP
   S: 173  fctlketpnaaehtiewa............vlfnklleeeageeevlekldseekeegkdkvkselksedeenfeeaieiavkafaktti 250
           +ct+ ++p +++h+++wa              +n +l++ a+   v  k   ++ +e +++v++ l +e+ ++fe++i++a+  f+ +++
   Q: 638  MCTVHSFPHNIDHCLTWArsefegllektpNEVNSFLSNPAQYAAVMRKAGDAQARELLERVSECLDKERCNTFEDCITWARLRFEDYFS 727
           *****************************9999********************************************************* PP
   S: 251  nsikqllksfecdivtkskspfwv......................................................sfcsnaealqvp 286
           n +kql+  f+ d  t+ ++pfw+                                                       +++++ ++ v+
   Q: 728  NRVKQLTFTFPEDAATSTGTPFWSapkrfprplqfsatdsshinflmaasilraesfgiaipewakntskladavnkvAVPKFEPKKGVN 817
           **************************************************************9999777666655555444444444444 PP
   S: 287  ekvekdeevvkasap.....lylllralerfekk..kgrkpgelsfekddds..avdlvtaaanlraeslgiepkldddlikeiagniip 367
             ++++ +++++++      +  ll++le+ +k   +g +++ ++fekddd   ++dl++ +an+ra +++i++ +d+ + k iag+iip
   Q: 818  IVTDEKATNLSSASVddvavINDLLAKLEEYAKGlpPGFQMKPIQFEKDDDTnfHMDLIAGLANMRARNYSIPE-VDKLKAKFIAGRIIP 906
           44444333333333366678899999999999975589************************************.*************** PP
   S: 368  aiattnavvgGlaaqEviKvvsg..kfeplknfflfdae 404
           aiat +a+  Gl+++E++Kv+ g  ++e ++n+f ++a+
   Q: 907  AIATSTAMATGLVCLELYKVIAGehPMEDYRNTFANLAI 945
           **********************999999******99875 PP

Organism

Zea mays

Protein Sequence
(Fasta)

MRCLRFLRRG FLAMLPSKRS ASADGGEPKR AKLGESPSAA RVGTSNGTRN GAAPEIDEDL 60
HSRQLAVYGR ETMRRLFAAD VLVSGLDGLG AEIAKNLALA GVKSVTIHDV KMVEMWDLSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCGTTGTG TTCGCGATGA GGTGCTTACG GTTTCTGCGC AGGGGTTTCC TCGCCATGCT 60
TCCGTCCAAG AGGTCTGCAA GCGCCGACGG CGGCGAGCCC AAGCGGGCTA AGCTGGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0436--Ligase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR032420--E1_4HB
IPR032418--E1_FCCH
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd
IPR018965--Ub-activating_enz_E1_C
IPR019572--UBA_E1_Cys
IPR018075--UBQ-activ_enz_E1
IPR018074--UBQ-activ_enz_E1_CS
IPR033127--UBQ-activ_enz_E1_Cys_AS
IPR000011--UBQ/SUMO-activ_enz_E1-like

PROSITE

PS00536--UBIQUITIN_ACTIVAT_1
PS00865--UBIQUITIN_ACTIVAT_2

Pfam

PF16191--E1_4HB
PF16190--E1_FCCH
PF09358--E1_UFD
PF00899--ThiF
PF10585--UBA_e1_thiolCys

PRINTS

PR01849--UBIQUITINACT

SMART

SM00985--UBA_e1_C

Gene Ontology

GO:0005524--F:ATP binding
GO:0008641--F:small protein activating enzyme activity
GO:0006464--P:cellular protein modification process

KEGG

zma:103633603

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000144	Aegilops tauschii	87.99	0.00e+00	1823.00
IUUC-Apl-004158	Anas platyrhynchos	39.20	0.00e+00	680.00
IUUC-Bdi-014009	Brachypodium distachyon	84.47	0.00e+00	1767.00
IUUC-Cel-018260	Caenorhabditis elegans	38.69	0.00e+00	665.00
IUUC-Cme-027290	Cyanidioschyzon merolae	38.76	0.00e+00	695.00
IUUC-Eeu-035323	Erinaceus europaeus	40.78	4.00e-154	538.00
IUUC-Ggr-039823	Gaeumannomyces graminis	44.52	0.00e+00	866.00
IUUC-Gga-040747	Gallus gallus	39.49	0.00e+00	676.00
IUUC-Hvu-047191	Hordeum vulgare	87.69	0.00e+00	1822.00
IUUC-Lpe-051299	Leersia perrieri	86.68	0.00e+00	1853.00
IUUC-Mor-057269	Magnaporthe oryzae	44.76	0.00e+00	849.00
IUUC-Mpo-057435	Magnaporthe poae	44.71	0.00e+00	845.00
IUUC-Mga-059721	Meleagris gallopavo	39.49	0.00e+00	656.00
IUUC-Mvi-060437	Microbotryum violaceum	43.14	0.00e+00	815.00
IUUC-Oan-073268	Ornithorhynchus anatinus	41.73	0.00e+00	633.00
IUUC-Oba-075934	Oryza barthii	86.67	0.00e+00	1847.00
IUUC-Obr-076244	Oryza brachyantha	86.40	0.00e+00	1790.00
IUUC-Ogl-077762	Oryza glaberrima	86.64	0.00e+00	1871.00
IUUC-Ogu-078305	Oryza glumaepatula	86.57	0.00e+00	1847.00
IUUC-Oin-080154	Oryza indica	86.74	0.00e+00	1872.00
IUUC-Olo-081089	Oryza longistaminata	86.92	0.00e+00	1876.00
IUUC-Ome-081171	Oryza meridionalis	83.13	0.00e+00	1728.00
IUUC-Oni-082447	Oryza nivara	86.46	0.00e+00	1855.00
IUUC-Opu-083863	Oryza punctata	88.22	0.00e+00	1836.00
IUUC-Oru-084469	Oryza rufipogon	86.86	0.00e+00	1849.00
IUUC-Osa-085625	Oryza sativa	86.84	0.00e+00	1855.00
IUUC-Olu-087687	Ostreococcus lucimarinus	59.19	0.00e+00	1138.00
IUUC-Ptr-090609	Pan troglodytes	38.50	0.00e+00	682.00
IUUC-Pma-094214	Petromyzon marinus	47.02	2.00e-33	134.00
IUUC-Sit-110294	Setaria italica	91.72	0.00e+00	2028.00
IUUC-Sbi-114774	Sorghum bicolor	95.68	0.00e+00	2108.00
IUUC-Tsy-119436	Tarsius syrichta	34.87	4.00e-162	565.00
IUUC-Tae-125702	Triticum aestivum	85.92	0.00e+00	1887.00
IUUC-Tur-126011	Triticum urartu	83.32	0.00e+00	1805.00
IUUC-Tbe-127714	Tupaia belangeri	37.17	5.00e-136	478.00
IUUC-Vpa-130716	Vicugna pacos	38.65	0.00e+00	669.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence