iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115461

Ensembl Protein ID

ENSSSCP00000004824.2

UniProt Accession

F1RQK4; F1RQK4_PIG

Genbank Protein ID

ENSSSCP00000004824

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEMK01111952

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000004473.2	ENSSSCT00000004941.2	ENSSSCP00000004824.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-34	117.2	181	218
UBD/Beta-Prp	2.70e-52	178.1	280	541

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWATDDGRLL 218
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl.....lrsl.sgheaevtavk..fspdgkilvtgseDrtikvw..dlstgkcvhtlkghedsv 97
           s +k++l ++++dgti  w ++ g+l      +++ +   ++v+ ++  fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+v
   Q: 280  SGSKRYLSSTGADGTICFWLWDAGTLkinprPAKFtERPRPGVQMICssFSAGGMFLATGSTDHIIRVYffGSGQPEKISELEFHTDKV 368
           67899***********999999999988988555547777888765522777888**************777779999*********** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgk 170
            s++fs +++++vsGs+d t+r+w+ + +++ +                  +++++  v++v+++  +n ++++ ++ t+++W++ tg+
   Q: 369  DSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSIlldmatrpagqnlqgiEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQ 457
           ********************************99***************888899999******************************* PP
   S: 171  llrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgsiriW 249
           l++ l g h+d v  l+   fd+  + l s+++dg v++wdl +g  +r++ +         v + + sp++++++++ s+g + i+
   Q: 458  LIHVLMG-HEDEVFVLEphpFDP--RVLFSAGHDGNVIVWDLARGVKIRSYFNMIegqghGAVFDCKCSPDGQHFACTDSHGHLLIF 541
           ******9.*********999999..89******************999998875544444566667777999999999999888887 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MSCERKGLSE LRSELYFLIA RFLEDGPCQQ AAQVRRRAGK EKYLLPRRTD WTGKEHPRTY 60
QNLVKYYRHL APDHLLQICH RLGPLLEQEI PQSVPGVQTL LGAGRQSLLR TNKSCRHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTTGTG AGAGGAAAGG CCTCTCGGAG CTGCGATCGG GTAAGTCGGG GGGCTGCCGG 60
GGCCGCTGGC ACCGGGCGAT TCCGCCCGCG GGCCCCCGCC CCCCGCCGCC CGGCCGCTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008286--P:insulin receptor signaling pathway
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	31.02	5.00e-56	213.00
IUUC-Aml-002299	Ailuropoda melanoleuca	93.54	0.00e+00	3064.00
IUUC-Atr-002600	Amborella trichopoda	30.70	3.00e-59	224.00
IUUC-Apl-003700	Anas platyrhynchos	83.33	0.00e+00	2717.00
IUUC-Aca-004474	Anolis carolinensis	79.27	0.00e+00	2669.00
IUUC-Aly-006406	Arabidopsis lyrata	30.24	2.00e-60	228.00
IUUC-Ath-006801	Arabidopsis thaliana	30.50	4.00e-61	230.00
IUUC-Ame-010718	Astyanax mexicanus	59.27	0.00e+00	928.00
IUUC-Bta-013125	Bos taurus	94.43	0.00e+00	3012.00
IUUC-Bdi-014797	Brachypodium distachyon	30.77	3.00e-52	201.00
IUUC-Bol-015737	Brassica oleracea	31.21	1.00e-64	241.00
IUUC-Bra-017961	Brassica rapa	31.70	6.00e-64	239.00
IUUC-Cja-018868	Callithrix jacchus	90.72	0.00e+00	3144.00
IUUC-Cfa-021179	Canis familiaris	92.54	0.00e+00	3038.00
IUUC-Cpo-022077	Cavia porcellus	87.32	0.00e+00	2896.00
IUUC-Csa-023618	Chlorocebus sabaeus	93.08	0.00e+00	3178.00
IUUC-Cin-025553	Ciona intestinalis	38.08	2.00e-107	382.00
IUUC-Csv-025813	Ciona savignyi	39.55	4.00e-153	535.00
IUUC-Dre-028508	Danio rerio	55.43	0.00e+00	1495.00
IUUC-Dno-030048	Dasypus novemcinctus	92.35	0.00e+00	3078.00
IUUC-Dor-030195	Dipodomys ordii	77.86	0.00e+00	1314.00
IUUC-Dme-031752	Drosophila melanogaster	48.04	1.00e-155	544.00
IUUC-Ete-032748	Echinops telfairi	84.26	0.00e+00	1154.00
IUUC-Eca-034274	Equus caballus	94.37	0.00e+00	3041.00
IUUC-Eeu-034688	Erinaceus europaeus	85.51	0.00e+00	1409.00
IUUC-Fca-035451	Felis catus	92.65	0.00e+00	2912.00
IUUC-Fal-037465	Ficedula albicollis	82.22	0.00e+00	2721.00
IUUC-Gmo-039451	Gadus morhua	68.58	0.00e+00	716.00
IUUC-Gga-040798	Gallus gallus	83.00	0.00e+00	2803.00
IUUC-Gac-042435	Gasterosteus aculeatus	52.91	0.00e+00	842.00
IUUC-Gma-043340	Glycine max	33.84	1.00e-57	219.00
IUUC-Ggo-045347	Gorilla gorilla	89.12	0.00e+00	1513.00
IUUC-Hsa-046757	Homo sapiens	93.08	0.00e+00	3146.00
IUUC-Hvu-047706	Hordeum vulgare	31.84	1.00e-37	150.00
IUUC-Itr-048843	Ictidomys tridecemlineatus	92.34	0.00e+00	1159.00
IUUC-Lch-050646	Latimeria chalumnae	75.52	0.00e+00	2597.00
IUUC-Lpe-051619	Leersia perrieri	29.80	1.00e-58	222.00
IUUC-Loc-051802	Lepisosteus oculatus	57.03	0.00e+00	935.00
IUUC-Laf-054140	Loxodonta africana	93.02	0.00e+00	3065.00
IUUC-Mcc-055061	Macaca mulatta	93.03	0.00e+00	3178.00
IUUC-Meu-056321	Macropus eugenii	56.59	0.00e+00	789.00
IUUC-Mtr-058094	Medicago truncatula	30.70	2.00e-61	231.00
IUUC-Mmr-060837	Microcebus murinus	92.48	0.00e+00	3107.00
IUUC-Mdo-061903	Monodelphis domestica	87.96	0.00e+00	3017.00
IUUC-Mmu-063772	Mus musculus	91.05	0.00e+00	3092.00
IUUC-Mac-065343	Musa acuminata	29.43	4.00e-64	240.00
IUUC-Mpu-066359	Mustela putorius furo	93.33	0.00e+00	2816.00
IUUC-Mlu-067928	Myotis lucifugus	91.85	0.00e+00	3053.00
IUUC-Nle-070094	Nomascus leucogenys	92.10	0.00e+00	3096.00
IUUC-Ont-072221	Oreochromis niloticus	69.44	0.00e+00	1172.00
IUUC-Oan-073185	Ornithorhynchus anatinus	84.34	0.00e+00	2747.00
IUUC-Ocu-074033	Oryctolagus cuniculus	90.46	0.00e+00	2701.00
IUUC-Oba-075709	Oryza barthii	30.79	9.00e-48	186.00
IUUC-Obr-076619	Oryza brachyantha	29.61	3.00e-60	227.00
IUUC-Opu-083233	Oryza punctata	29.13	4.00e-55	210.00
IUUC-Oru-085195	Oryza rufipogon	30.79	7.00e-48	186.00
IUUC-Ola-086648	Oryzias latipes	69.61	0.00e+00	1171.00
IUUC-Olu-087745	Ostreococcus lucimarinus	28.40	3.00e-50	194.00
IUUC-Oga-088578	Otolemur garnettii	93.24	0.00e+00	3014.00
IUUC-Oar-090247	Ovis aries	94.60	0.00e+00	3013.00
IUUC-Ptr-091266	Pan troglodytes	93.09	0.00e+00	3058.00
IUUC-Pan-092734	Papio anubis	93.14	0.00e+00	3178.00
IUUC-Psi-093408	Pelodiscus sinensis	60.49	0.00e+00	959.00
IUUC-Pma-094427	Petromyzon marinus	65.22	2.00e-122	431.00
IUUC-Ppa-095793	Physcomitrella patens	29.92	3.00e-68	254.00
IUUC-Pfo-096191	Poecilia formosa	69.29	0.00e+00	1932.00
IUUC-Pab-098402	Pongo abelii	93.14	0.00e+00	3147.00
IUUC-Pop-099803	Populus trichocarpa	32.26	1.00e-69	258.00
IUUC-Pca-101128	Procavia capensis	81.14	0.00e+00	2709.00
IUUC-Ppe-101849	Prunus persica	30.60	2.00e-65	244.00
IUUC-Pva-103058	Pteropus vampyrus	95.80	0.00e+00	1575.00
IUUC-Rno-106013	Rattus norvegicus	90.06	0.00e+00	2970.00
IUUC-Sha-107496	Sarcophilus harrisii	88.19	0.00e+00	2950.00
IUUC-Sly-111348	Solanum lycopersicum	30.39	9.00e-62	232.00
IUUC-Sar-113520	Sorex araneus	91.71	0.00e+00	1536.00
IUUC-Sbi-114195	Sorghum bicolor	29.59	5.00e-57	215.00
IUUC-Tgu-116821	Taeniopygia guttata	82.58	0.00e+00	2757.00
IUUC-Tru-117824	Takifugu rubripes	50.57	0.00e+00	823.00
IUUC-Tsy-119132	Tarsius syrichta	81.34	0.00e+00	2430.00
IUUC-Tni-120716	Tetraodon nigroviridis	69.24	0.00e+00	1181.00
IUUC-Tca-121615	Theobroma cacao	29.58	2.00e-56	214.00
IUUC-Tae-125478	Triticum aestivum	31.18	1.00e-63	239.00
IUUC-Tur-126809	Triticum urartu	31.18	1.00e-63	239.00
IUUC-Tbe-127479	Tupaia belangeri	91.79	0.00e+00	1435.00
IUUC-Ttr-128427	Tursiops truncatus	89.68	0.00e+00	2957.00
IUUC-Vpa-130160	Vicugna pacos	91.84	0.00e+00	2935.00
IUUC-Vvi-131332	Vitis vinifera	31.07	1.00e-65	245.00
IUUC-Xtr-132717	Xenopus tropicalis	71.72	0.00e+00	2413.00
IUUC-Xma-134120	Xiphophorus maculatus	71.04	0.00e+00	1132.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence