iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074220

Ensembl Protein ID

ENSOCUP00000017947.1

UniProt Accession

G1TLU5; G1TLU5_RABIT

Genbank Protein ID

ENSOCUP00000017947

Protein Name

Small ubiquitin-related modifier

Genbank Nucleotide ID

AAGW02045478

Gene Name

SUMO1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000024022.1	ENSOCUT00000025338.1	ENSOCUP00000017947.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UBL/SUMO	3.70e-30	104.5	20	96
ULD/UDP/UBQ/UBQ_Other	7.90e-07	28.9	28	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UBL/SUMO

   S: 7    apvslkvagqdGsevlfklklsaqlkklmeavYvkrinldensvrfvfngqkireqetpeelevededkiellcqksG 84
           ++++lkv gqd+se++fk+k++++lkkl+e+ Y++r+++ +ns+rf+f+gq+i++++tp+el++e+ed+ie++++++G
   Q: 20   EYIKLKVIGQDSSEIHFKVKMTTHLKKLKES-YCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQTG 96
           69*****************************.*********************************************9 PP

ULD/UDP/UBQ/UBQ_Other

   S: 7    sldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllekk 73
             d+se  +kv+ ++  ++LKe   +++g+p+++ r +++G+ + d++t +++g+ ++++i +++++
   Q: 28   GQDSSEIHFKVKMTTHLKKLKESYCQRQGVPMNSLRFLFEGQRIADNHTPKELGMEEEDVIEVYQEQ 94
           445557778899999*************************************************986 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MSDQEAKPST EDLGDKKEGE YIKLKVIGQD SSEIHFKVKM TTHLKKLKES YCQRQGVPMN 60
SLRFLFEGQR IADNHTPKEL GMEEEDVIEV YQEQTGSFNG L 101

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGACC AGGAGGCAAA ACCTTCAACT GAGGACTTGG GGGATAAGAA GGAAGGAGAG 60
TACATTAAAC TCAAAGTCAT TGGACAGGAT AGCAGTGAGA TTCATTTCAA AGTGAAAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR022617--Rad60/SUMO-like_dom
IPR033950--Sumo
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF11976--Rad60-SLD

SMART

SM00213--UBQ

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0097165--C:nuclear stress granule
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008076--C:voltage-gated potassium channel complex
GO:0001741--C:XY body
GO:0015459--F:potassium channel regulator activity
GO:0003723--F:RNA binding
GO:0008134--F:transcription factor binding
GO:0071276--P:cellular response to cadmium ion
GO:0034605--P:cellular response to heat
GO:0045759--P:negative regulation of action potential
GO:1902260--P:negative regulation of delayed rectifier potassium channel activity
GO:0043392--P:negative regulation of DNA binding
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0060021--P:palate development
GO:0030578--P:PML body organization
GO:1901896--P:positive regulation of calcium-transporting ATPase activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0031334--P:positive regulation of protein complex assembly
GO:0090204--P:protein localization to nuclear pore
GO:0050821--P:protein stabilization
GO:0016925--P:protein sumoylation
GO:0086004--P:regulation of cardiac muscle cell contraction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004710	Anolis carolinensis	97.92	8.00e-52	194.00
IUUC-Ame-011662	Astyanax mexicanus	84.69	3.00e-44	169.00
IUUC-Cel-018251	Caenorhabditis elegans	65.00	2.00e-28	116.00
IUUC-Dre-028383	Danio rerio	86.46	2.00e-43	166.00
IUUC-Eeu-034822	Erinaceus europaeus	100.00	4.00e-53	198.00
IUUC-Gac-042112	Gasterosteus aculeatus	85.71	5.00e-46	175.00
IUUC-Lch-049881	Latimeria chalumnae	84.38	1.00e-38	150.00
IUUC-Loc-052189	Lepisosteus oculatus	89.47	3.00e-47	179.00
IUUC-Mcc-055059	Macaca mulatta	81.37	2.00e-45	174.00
IUUC-Ont-071436	Oreochromis niloticus	85.71	5.00e-46	175.00
IUUC-Oan-072986	Ornithorhynchus anatinus	96.30	8.00e-26	107.00
IUUC-Ola-086373	Oryzias latipes	84.69	1.00e-44	170.00
IUUC-Oga-088024	Otolemur garnettii	93.07	1.00e-52	197.00
IUUC-Pfo-096306	Poecilia formosa	85.71	2.00e-45	173.00
IUUC-Pva-102353	Pteropus vampyrus	100.00	3.00e-43	166.00
IUUC-Sar-113550	Sorex araneus	100.00	1.00e-50	190.00
IUUC-Sre-115172	Sporisorium reilianum	52.56	5.00e-19	85.10
IUUC-Tru-117752	Takifugu rubripes	85.71	2.00e-46	176.00
IUUC-Tsy-119358	Tarsius syrichta	100.00	2.00e-40	157.00
IUUC-Tni-120621	Tetraodon nigroviridis	85.71	9.00e-46	174.00
IUUC-Ttr-128166	Tursiops truncatus	100.00	7.00e-53	199.00
IUUC-Uma-129444	Ustilago maydis	52.56	1.00e-19	87.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence