iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dse-031543

Ensembl Protein ID

EME42492

UniProt Accession

N1PJA6; N1PJA6_DOTSN

Genbank Protein ID

EME42492.1

Protein Name

Coatomer subunit alpha

Genbank Nucleotide ID

KB446541

Gene Name

DOTSEDRAFT_73359

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
DOTSEDRAFT_73359	EME42492	EME42492

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.20e-32	109.9	97	129
UBD/Beta-Prp	3.20e-76	255.7	8	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           gH d v+ + f ++ + ++s+sdD ti++W++ 
   Q: 97   GHLDYVRTVFFhHElPWIISSSDDQTIRIWNWQ 129
           8********5597789***************75 PP

UBD/Beta-Prp

   S: 3    ktlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfs 103
            t +++++s+ + ++f+p++++++++  ++ti++wd+++g+l+ ++++h+++v+ ++f+++++++v+g++D+ ikvw+++t+ c+ tl+gh d+v+++ f+
   Q: 8    LTKFESKSSRAKGIAFHPKRPWILVSLHSSTIQLWDYRMGTLIDRFEEHDGPVRGIDFHKTQPLFVSGGDDYKIKVWSYQTRRCLFTLNGHLDYVRTVFFH 108
           67889999********************************************************************************************* PP
   S: 104  psgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...............................ktgkllr 173
            +  +++s s+d+tir+w++++++ +  t +gh++ ++c+++hp+++l+vs+slD+ vr+Wd+                               +t+ +++
   Q: 109  HELPWIISSSDDQTIRIWNWQNRSLIC-TMTGHNHYTMCAQFHPKEDLVVSASLDQSVRVWDIsglrkkhsaptsmsfedqiaranqnqadmfgNTDAVVK 208
           **************************9.*********************************************************9999999977777777 PP
   S: 174  tltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvav 272
              +gh++ v++++f+++ + +vs+++d+ vklw +++++   v+t++gh +n +   f+p++++++s+++D++ir+Wdl  ++ +++++++n++++ +a+
   Q: 209  FVLEGHDRGVNWVAFHPTLPLIVSAGDDRLVKLWRMSETKAweVDTCRGHFQNASACLFHPHQDLILSVGEDKTIRVWDLNRRTSVQSFKRENDRFWVIAA 309
           66777********************************888778********************************************************** PP
   S: 273  lsfgdnvlvlgsedskvniwklkknep 299
            +++ n +++g  d+ v+++kl++++p
   Q: 310  -HPEINLFAAG-HDNGVMVFKLERERP 334
           .6666555555.478*******98775 PP

Organism

Dothistroma septosporum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MASTPSMLTK FESKSSRAKG IAFHPKRPWI LVSLHSSTIQ LWDYRMGTLI DRFEEHDGPV 60
RGIDFHKTQP LFVSGGDDYK IKVWSYQTRR CLFTLNGHLD YVRTVFFHHE LPWIISSSDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACACTTCTG CCCGCCAGCT GTACAGCACC ATCGATTCAG CTGTCCATTC TCCATCTCGC 60
TCATTGGACG TATCGCGACC GCCATCTGGG TGCGCCAACA ATCCCCTGGA GCTGAGGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000064	Aegilops tauschii	54.29	0.00e+00	971.00
IUUC-Aml-001758	Ailuropoda melanoleuca	46.97	0.00e+00	1170.00
IUUC-Atr-002493	Amborella trichopoda	54.63	0.00e+00	948.00
IUUC-Apl-003385	Anas platyrhynchos	41.55	0.00e+00	858.00
IUUC-Aca-005154	Anolis carolinensis	72.33	5.00e-94	334.00
IUUC-Aly-006020	Arabidopsis lyrata	54.51	0.00e+00	951.00
IUUC-Ath-007058	Arabidopsis thaliana	54.51	0.00e+00	949.00
IUUC-Ago-007992	Ashbya gossypii	51.39	0.00e+00	1215.00
IUUC-Acl-008027	Aspergillus clavatus	74.38	0.00e+00	1838.00
IUUC-Afl-008644	Aspergillus flavus	75.21	0.00e+00	1840.00
IUUC-Afu-008964	Aspergillus fumigatus	74.88	0.00e+00	1859.00
IUUC-Ani-009379	Aspergillus nidulans	82.79	0.00e+00	1495.00
IUUC-Ang-009756	Aspergillus niger	75.58	0.00e+00	1861.00
IUUC-Aor-010174	Aspergillus oryzae	75.21	0.00e+00	1838.00
IUUC-Ate-010302	Aspergillus terreus	74.14	0.00e+00	1878.00
IUUC-Ame-011229	Astyanax mexicanus	47.03	0.00e+00	1165.00
IUUC-Bgr-012300	Blumeria graminis	72.61	0.00e+00	1767.00
IUUC-Bta-012524	Bos taurus	47.31	0.00e+00	1169.00
IUUC-Bci-013781	Botrytis cinerea	75.70	0.00e+00	1878.00
IUUC-Bdi-014549	Brachypodium distachyon	45.65	0.00e+00	1100.00
IUUC-Bol-015925	Brassica oleracea	54.75	0.00e+00	952.00
IUUC-Bra-016978	Brassica rapa	54.03	0.00e+00	944.00
IUUC-Cel-018115	Caenorhabditis elegans	51.78	0.00e+00	912.00
IUUC-Cja-019107	Callithrix jacchus	46.92	0.00e+00	1151.00
IUUC-Cfa-020675	Canis familiaris	46.72	0.00e+00	1142.00
IUUC-Cpo-021813	Cavia porcellus	47.23	0.00e+00	1177.00
IUUC-Cre-022969	Chlamydomonas reinhardtii	55.07	0.00e+00	983.00
IUUC-Csa-023523	Chlorocebus sabaeus	47.07	0.00e+00	1173.00
IUUC-Cho-024704	Choloepus hoffmanni	61.34	2.00e-121	428.00
IUUC-Cin-025572	Ciona intestinalis	46.49	0.00e+00	1137.00
IUUC-Csv-025864	Ciona savignyi	54.77	0.00e+00	948.00
IUUC-Cgl-026510	Colletotrichum gloeosporioides	74.88	0.00e+00	1863.00
IUUC-Cne-027053	Cryptococcus neoformans	54.34	0.00e+00	1303.00
IUUC-Cme-027222	Cyanidioschyzon merolae	41.11	4.00e-141	494.00
IUUC-Dre-027421	Danio rerio	48.26	0.00e+00	1173.00
IUUC-Dno-029303	Dasypus novemcinctus	47.07	0.00e+00	1178.00
IUUC-Dor-030290	Dipodomys ordii	46.77	4.00e-147	514.00
IUUC-Dme-031945	Drosophila melanogaster	55.68	0.00e+00	965.00
IUUC-Ete-032873	Echinops telfairi	45.70	0.00e+00	1024.00
IUUC-Eca-033773	Equus caballus	46.22	0.00e+00	1130.00
IUUC-Eeu-034874	Erinaceus europaeus	34.85	4.00e-149	520.00
IUUC-Fca-035739	Felis catus	46.32	0.00e+00	1150.00
IUUC-Fal-037263	Ficedula albicollis	44.29	0.00e+00	1031.00
IUUC-Fox-037738	Fusarium oxysporum	74.49	0.00e+00	1902.00
IUUC-Fso-038153	Fusarium solani	74.30	0.00e+00	1875.00
IUUC-Gmo-039602	Gadus morhua	45.05	0.00e+00	1095.00
IUUC-Ggr-039931	Gaeumannomyces graminis	74.90	0.00e+00	1815.00
IUUC-Gga-040590	Gallus gallus	46.75	0.00e+00	1175.00
IUUC-Gac-041318	Gasterosteus aculeatus	46.66	0.00e+00	1161.00
IUUC-Gma-043894	Glycine max	46.32	0.00e+00	1115.00
IUUC-Ggo-045029	Gorilla gorilla	46.82	0.00e+00	1165.00
IUUC-Hsa-046078	Homo sapiens	46.82	0.00e+00	1166.00
IUUC-Hvu-047556	Hordeum vulgare	46.16	0.00e+00	1100.00
IUUC-Itr-048881	Ictidomys tridecemlineatus	38.05	1.00e-176	612.00
IUUC-Kpa-049256	Komagataella pastoris	52.79	0.00e+00	1303.00
IUUC-Lch-049706	Latimeria chalumnae	48.03	0.00e+00	1168.00
IUUC-Lpe-051316	Leersia perrieri	54.17	0.00e+00	967.00
IUUC-Loc-051867	Lepisosteus oculatus	42.06	0.00e+00	781.00
IUUC-Lma-053138	Leptosphaeria maculans	79.41	0.00e+00	1951.00
IUUC-Laf-053510	Loxodonta africana	47.53	0.00e+00	1170.00
IUUC-Mcc-055836	Macaca mulatta	46.97	0.00e+00	1169.00
IUUC-Meu-056238	Macropus eugenii	51.47	0.00e+00	707.00
IUUC-Mor-057172	Magnaporthe oryzae	74.69	0.00e+00	1875.00
IUUC-Mpo-057300	Magnaporthe poae	73.98	0.00e+00	1817.00
IUUC-Mtr-058248	Medicago truncatula	45.59	0.00e+00	1103.00
IUUC-Mla-059019	Melampsora laricipopulina	54.65	0.00e+00	1343.00
IUUC-Mga-059499	Meleagris gallopavo	46.76	0.00e+00	1171.00
IUUC-Mvi-060336	Microbotryum violaceum	55.30	0.00e+00	1336.00
IUUC-Mmr-061102	Microcebus murinus	46.60	0.00e+00	1162.00
IUUC-Mdo-062594	Monodelphis domestica	47.67	0.00e+00	1182.00
IUUC-Mmu-063736	Mus musculus	47.12	0.00e+00	1167.00
IUUC-Mac-065398	Musa acuminata	43.11	0.00e+00	993.00
IUUC-Mpu-066701	Mustela putorius furo	46.59	0.00e+00	1169.00
IUUC-Mlu-067392	Myotis lucifugus	47.20	0.00e+00	1164.00
IUUC-Nfi-068270	Neosartorya fischeri	75.04	0.00e+00	1840.00
IUUC-Ncr-068892	Neurospora crassa	73.51	0.00e+00	1827.00
IUUC-Nle-069634	Nomascus leucogenys	59.97	0.00e+00	873.00
IUUC-Opr-070952	Ochotona princeps	35.23	5.00e-153	533.00
IUUC-Ont-072488	Oreochromis niloticus	46.62	0.00e+00	1161.00
IUUC-Ocu-074211	Oryctolagus cuniculus	47.15	0.00e+00	1174.00
IUUC-Oba-075761	Oryza barthii	54.29	0.00e+00	968.00
IUUC-Obr-076429	Oryza brachyantha	54.37	0.00e+00	966.00
IUUC-Ogl-077364	Oryza glaberrima	54.29	0.00e+00	969.00
IUUC-Ogu-078257	Oryza glumaepatula	54.37	0.00e+00	966.00
IUUC-Oin-080029	Oryza indica	54.25	0.00e+00	968.00
IUUC-Olo-080466	Oryza longistaminata	54.77	0.00e+00	963.00
IUUC-Ome-081993	Oryza meridionalis	56.20	0.00e+00	927.00
IUUC-Oni-082874	Oryza nivara	54.49	0.00e+00	968.00
IUUC-Opu-083370	Oryza punctata	54.17	0.00e+00	967.00
IUUC-Oru-084274	Oryza rufipogon	54.37	0.00e+00	967.00
IUUC-Osa-085565	Oryza sativa	54.37	0.00e+00	967.00
IUUC-Ola-086921	Oryzias latipes	46.63	0.00e+00	1149.00
IUUC-Olu-087639	Ostreococcus lucimarinus	47.30	0.00e+00	1139.00
IUUC-Oga-087991	Otolemur garnettii	44.67	0.00e+00	1097.00
IUUC-Oar-089590	Ovis aries	47.31	0.00e+00	1178.00
IUUC-Ptr-090808	Pan troglodytes	46.82	0.00e+00	1165.00
IUUC-Pan-092475	Papio anubis	46.79	0.00e+00	1162.00
IUUC-Psi-093044	Pelodiscus sinensis	50.54	0.00e+00	845.00
IUUC-Pno-094839	Phaeosphaeria nodorum	78.08	0.00e+00	1887.00
IUUC-Ppa-095785	Physcomitrella patens	49.07	0.00e+00	1179.00
IUUC-Pfo-097493	Poecilia formosa	47.42	0.00e+00	1159.00
IUUC-Pab-098497	Pongo abelii	47.07	0.00e+00	1174.00
IUUC-Pop-099992	Populus trichocarpa	55.53	0.00e+00	960.00
IUUC-Pca-100413	Procavia capensis	53.58	2.00e-180	625.00
IUUC-Ppe-101899	Prunus persica	54.63	0.00e+00	963.00
IUUC-Pva-102126	Pteropus vampyrus	45.46	0.00e+00	1115.00
IUUC-Pgr-103376	Puccinia graminis	54.08	0.00e+00	1340.00
IUUC-Ptt-103978	Puccinia triticina	48.71	0.00e+00	1136.00
IUUC-Pte-104126	Pyrenophora teres	77.92	0.00e+00	1861.00
IUUC-Pyt-104778	Pyrenophora triticirepentis	71.23	0.00e+00	1442.00
IUUC-Rno-105428	Rattus norvegicus	47.78	0.00e+00	1180.00
IUUC-Sce-106464	Saccharomyces cerevisiae	49.72	0.00e+00	1184.00
IUUC-Sha-107301	Sarcophilus harrisii	46.84	0.00e+00	1153.00
IUUC-Sja-107961	Schizosaccharomyces japonicus	52.64	0.00e+00	1332.00
IUUC-Spo-108217	Schizosaccharomyces pombe	53.57	0.00e+00	1360.00
IUUC-Ssl-108643	Sclerotinia sclerotiorum	76.15	0.00e+00	1879.00
IUUC-Smo-109582	Selaginella moellendorffii	55.12	0.00e+00	996.00
IUUC-Sit-109697	Setaria italica	53.69	0.00e+00	960.00
IUUC-Sly-111759	Solanum lycopersicum	46.02	0.00e+00	1103.00
IUUC-Stu-112564	Solanum tuberosum	46.02	0.00e+00	1102.00
IUUC-Sar-113313	Sorex araneus	37.58	2.00e-145	508.00
IUUC-Sbi-114388	Sorghum bicolor	53.81	0.00e+00	962.00
IUUC-Sre-115209	Sporisorium reilianum	63.65	0.00e+00	1134.00
IUUC-Ssc-115933	Sus scrofa	47.31	0.00e+00	1176.00
IUUC-Tgu-117109	Taeniopygia guttata	41.98	7.00e-87	312.00
IUUC-Tru-117772	Takifugu rubripes	46.06	0.00e+00	1137.00
IUUC-Tsy-119105	Tarsius syrichta	46.53	0.00e+00	919.00
IUUC-Tni-120556	Tetraodon nigroviridis	34.45	0.00e+00	646.00
IUUC-Tca-120918	Theobroma cacao	55.11	0.00e+00	972.00
IUUC-Tre-121951	Trichoderma reesei	73.87	0.00e+00	1820.00
IUUC-Tvi-122359	Trichoderma virens	73.40	0.00e+00	1835.00
IUUC-Tae-125527	Triticum aestivum	45.39	0.00e+00	1090.00
IUUC-Tur-126754	Triticum urartu	45.79	0.00e+00	1091.00
IUUC-Tme-127170	Tuber melanosporum	73.85	0.00e+00	1842.00
IUUC-Tbe-127882	Tupaia belangeri	62.82	7.00e-122	430.00
IUUC-Ttr-128217	Tursiops truncatus	45.54	0.00e+00	1110.00
IUUC-Uma-129337	Ustilago maydis	63.06	0.00e+00	1124.00
IUUC-Vda-129828	Verticillium dahliae	73.10	0.00e+00	1811.00
IUUC-Vpa-130537	Vicugna pacos	46.55	0.00e+00	1151.00
IUUC-Vvi-130958	Vitis vinifera	54.99	0.00e+00	971.00
IUUC-Xtr-132857	Xenopus tropicalis	45.61	0.00e+00	1090.00
IUUC-Xma-133138	Xiphophorus maculatus	47.34	0.00e+00	1158.00
IUUC-Yli-134399	Yarrowia lipolytica	60.54	0.00e+00	1067.00
IUUC-Zma-135612	Zea mays	45.34	0.00e+00	1083.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence