iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tae-125732

Ensembl Protein ID

TRIAE_CS42_5AL_TGACv1_374774_AA1208800.2

UniProt Accession

A0A1D5YFX0; A0A1D5YFX0_WHEAT

Protein Name

Coatomer subunit alpha

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TRIAE_CS42_5AL_TGACv1_374774_AA1208800	TRIAE_CS42_5AL_TGACv1_374774_AA1208800.1	TRIAE_CS42_5AL_TGACv1_374774_AA1208800.1
TRIAE_CS42_5AL_TGACv1_374774_AA1208800	TRIAE_CS42_5AL_TGACv1_374774_AA1208800.2	TRIAE_CS42_5AL_TGACv1_374774_AA1208800.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-38	131.4	50	86
UBD/Beta-Prp	4.10e-77	262.0	3	323

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           H ++v++++f  + +l+vsG+dD +ikvW+++t+++l
   Q: 50   HDGPVRGVHFhKTqPLFVSGGDDYKIKVWNYKTHRCL 86
           99*********4459********************98 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgse 72
           t +++++++++ ++f+p +++++++  +g ++ wd+++g+ll ++ +h+++v+ v f+++++++v+g++
   Q: 3    TKFETKSNRVKGLAFHPRRPWILASLHSGVVQMWDYRMGTLLDRFDEHDGPVRGVHFHKTQPLFVSGGD 71
           67889999************************************************************* PP
   S: 73   DrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvn 141
           D+ ikvw+++t  c+ tl+gh d++++++f+ +  ++vs+s+d+tirvw++++++c+  +l+gh++ v+
   Q: 72   DYKIKVWNYKTHRCLFTLHGHLDYIRTVQFHDEHPWIVSASDDQTIRVWNWQSRTCVA-VLTGHNHYVM 139
           **********************************************************.********** PP
   S: 142  cvvvhpdgnllvsGslDrtvrlWdl..........................ktgkllrtl.......tg 177
           c+++hp+++l+vs+slD+tvr+Wd+                                           +
   Q: 140  CASFHPKEDLVVSASLDQTVRVWDIgalrkkssspaddimrltqmntdlfgG-------IdavvkyvLE 201
           **********************************999999666655555553.......0444444555 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgec..vrtlnghtdnvksvrfspnderlvsgssDg 244
           gh++ v++ sf+++ + +vsg++d++vklw +  ++   v+tl+gh +nv++v f+ +++++vs s+D+
   Q: 202  GHDRGVNWASFHPTLPLIVSGADDRQVKLWRMNDTKAweVDTLRGHMNNVSCVLFHAKQDIIVSNSEDK 270
           5********************************777668****************************** PP
   S: 245  siriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklkknep 299
           sir+Wd ++++ ++t+ +++++++  a+ +++ n l++g  ds   ++kl++++p
   Q: 271  SIRVWDATKRTGIQTFRREHDRFWVLAA-HPEMNLLAAG-HDSGMIVFKLERERP 323
           ****************************.6666655555.689999999988765 PP

Organism

Triticum aestivum

Functional Description
(View)

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

Protein Sequence
(Fasta)

MLTKFETKSN RVKGLAFHPR RPWILASLHS GVVQMWDYRM GTLLDRFDEH DGPVRGVHFH 60
KTQPLFVSGG DDYKIKVWNY KTHRCLFTLH GHLDYIRTVQ FHDEHPWIVS ASDDQTIRVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCCGAGCAA GTCAAGTAGG AGGGGGGAAA GGAAAGAAAA ACCCACCCAG CCCAGCACAC 60
ACATCTTCTT CCCTTCGCTT CTCCGAGATC CAAATCACCA AACTGAGCCC AGATCCACCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR016391--Coatomer_asu
IPR010714--Coatomer_asu_C
IPR006692--Coatomer_WD-assoc_reg
IPR020472--G-protein_beta_WD-40_rep
IPR011048--Haem_d1
IPR011990--TPR-like_helical_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF06957--COPI_C
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006886--P:intracellular protein transport
GO:0016192--P:vesicle-mediated transport

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000201	Aegilops tauschii	99.92	0.00e+00	2405.00
IUUC-Afu-008964	Aspergillus fumigatus	48.10	0.00e+00	1134.00
IUUC-Cme-027222	Cyanidioschyzon merolae	42.65	3.00e-146	514.00
IUUC-Dre-027421	Danio rerio	54.32	0.00e+00	1344.00
IUUC-Mcc-055836	Macaca mulatta	54.42	0.00e+00	1349.00
IUUC-Mdo-062594	Monodelphis domestica	55.30	0.00e+00	1384.00
IUUC-Oga-087991	Otolemur garnettii	52.30	0.00e+00	1269.00
IUUC-Pva-102126	Pteropus vampyrus	52.41	0.00e+00	1281.00
IUUC-Pgr-103376	Puccinia graminis	50.65	0.00e+00	1219.00
IUUC-Ptt-103978	Puccinia triticina	44.37	0.00e+00	981.00
IUUC-Sar-113313	Sorex araneus	41.98	0.00e+00	636.00
IUUC-Tur-126016	Triticum urartu	99.57	0.00e+00	2323.00
IUUC-Ttr-128217	Tursiops truncatus	52.41	0.00e+00	1282.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence