iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004718

Ensembl Protein ID

ENSACAP00000016400.2

UniProt Accession

H9GNH0; H9GNH0_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KMT2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016679.3	ENSACAT00000016725.3	ENSACAP00000016400.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.60e-23	80.2	1173	1231

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek...slveCekCrewfHpaClkls.....veeelpnsekwiCpkCr 52
           ++C++C  ++ed++   ++++C kC++w+H++C +ls     + ++lp+s  ++C+ C+
   Q: 1173 NYCPICLHCYEDNDyesKMMQCAKCDHWVHAKCEGLSdegyeILSNLPESVVYACRPCC 1231
           79**********98888*****************************************7 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

AQQEEFLGFH LEDEVTQSSR RAALRSKRGN SKRGMGKEEK STALPVRKKE RKKRAATEDT 60
PPKRLVKQKA VESQRERMVK ALAELLQKSK RSPARIGRPP ISGPKVARPR GRPPGSSRKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCAACAGG AAGAGTTCCT GGGCTTCCAT TTGGAGGATG AAGTCACTCA GAGCTCACGA 60
CGGGCTGCAT TGAGATCTAA AAGAGGTAAC AGTGTTATTT CAGGTGTTAT TTCAGGCTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR017956--AT_hook_DNA-bd_motif
IPR001487--Bromodomain
IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
PF02008--zf-CXXC

SMART

SM00384--AT_hook
SM00542--FYRC
SM00541--FYRN
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0035097--C:histone methyltransferase complex
GO:0003677--F:DNA binding
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0008270--F:zinc ion binding
GO:0016458--P:gene silencing
GO:0080182--P:histone H3-K4 trimethylation
GO:0007613--P:memory
GO:0009994--P:oocyte differentiation
GO:0001541--P:ovarian follicle development
GO:0030728--P:ovulation
GO:0051569--P:regulation of histone H3-K4 methylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002367	Ailuropoda melanoleuca	63.81	0.00e+00	1326.00
IUUC-Atr-002455	Amborella trichopoda	50.00	1.00e-38	155.00
IUUC-Aly-006448	Arabidopsis lyrata	50.00	2.00e-39	157.00
IUUC-Ath-006690	Arabidopsis thaliana	46.10	3.00e-36	147.00
IUUC-Ame-010705	Astyanax mexicanus	44.85	0.00e+00	978.00
IUUC-Bta-013578	Bos taurus	56.06	0.00e+00	1382.00
IUUC-Bol-016540	Brassica oleracea	40.28	3.00e-37	150.00
IUUC-Cja-019138	Callithrix jacchus	56.59	0.00e+00	1419.00
IUUC-Cfa-020020	Canis familiaris	63.19	0.00e+00	1291.00
IUUC-Cpo-021552	Cavia porcellus	60.86	0.00e+00	1296.00
IUUC-Cre-022891	Chlamydomonas reinhardtii	53.12	1.00e-38	156.00
IUUC-Csa-024216	Chlorocebus sabaeus	63.73	0.00e+00	1310.00
IUUC-Cin-025724	Ciona intestinalis	55.73	4.00e-97	349.00
IUUC-Dre-027440	Danio rerio	47.61	0.00e+00	975.00
IUUC-Dno-029583	Dasypus novemcinctus	62.67	0.00e+00	1337.00
IUUC-Dor-030903	Dipodomys ordii	56.41	0.00e+00	1372.00
IUUC-Dme-032023	Drosophila melanogaster	49.00	3.00e-96	348.00
IUUC-Eca-034026	Equus caballus	66.29	0.00e+00	1240.00
IUUC-Eeu-034687	Erinaceus europaeus	62.40	0.00e+00	736.00
IUUC-Fca-036311	Felis catus	63.78	0.00e+00	1327.00
IUUC-Gmo-039265	Gadus morhua	46.76	0.00e+00	863.00
IUUC-Gac-042202	Gasterosteus aculeatus	49.56	0.00e+00	769.00
IUUC-Gma-044380	Glycine max	50.33	6.00e-37	149.00
IUUC-Ggo-044791	Gorilla gorilla	65.00	0.00e+00	1285.00
IUUC-Hsa-046988	Homo sapiens	63.29	0.00e+00	1308.00
IUUC-Hvu-047762	Hordeum vulgare	36.09	5.00e-19	89.00
IUUC-Itr-048907	Ictidomys tridecemlineatus	57.61	0.00e+00	1443.00
IUUC-Lpe-051476	Leersia perrieri	30.80	4.00e-22	100.00
IUUC-Loc-052252	Lepisosteus oculatus	47.55	0.00e+00	857.00
IUUC-Laf-053703	Loxodonta africana	63.94	0.00e+00	1332.00
IUUC-Mcc-054782	Macaca mulatta	62.73	0.00e+00	1306.00
IUUC-Meu-056046	Macropus eugenii	57.92	0.00e+00	1394.00
IUUC-Mtr-058327	Medicago truncatula	42.22	4.00e-37	150.00
IUUC-Mmr-061316	Microcebus murinus	62.60	0.00e+00	1266.00
IUUC-Mdo-062648	Monodelphis domestica	58.89	0.00e+00	1353.00
IUUC-Mmu-063579	Mus musculus	63.48	0.00e+00	1326.00
IUUC-Mac-064935	Musa acuminata	34.93	2.00e-28	121.00
IUUC-Mpu-066710	Mustela putorius furo	63.26	0.00e+00	1312.00
IUUC-Mlu-067559	Myotis lucifugus	60.64	0.00e+00	1309.00
IUUC-Nle-070085	Nomascus leucogenys	63.54	0.00e+00	1306.00
IUUC-Opr-071148	Ochotona princeps	62.66	0.00e+00	1321.00
IUUC-Ont-071626	Oreochromis niloticus	44.75	0.00e+00	918.00
IUUC-Ocu-074475	Oryctolagus cuniculus	55.56	0.00e+00	1380.00
IUUC-Obr-076458	Oryza brachyantha	34.31	7.00e-26	112.00
IUUC-Ogl-077851	Oryza glaberrima	34.76	2.00e-25	110.00
IUUC-Ogu-078706	Oryza glumaepatula	32.54	9.00e-26	112.00
IUUC-Oin-079802	Oryza indica	30.23	9.00e-21	95.10
IUUC-Olo-080577	Oryza longistaminata	47.71	1.00e-34	141.00
IUUC-Osa-085421	Oryza sativa	34.76	3.00e-25	110.00
IUUC-Ola-086609	Oryzias latipes	49.08	0.00e+00	804.00
IUUC-Oga-088140	Otolemur garnettii	56.47	0.00e+00	1378.00
IUUC-Oar-089447	Ovis aries	56.52	0.00e+00	1391.00
IUUC-Ptr-090902	Pan troglodytes	63.29	0.00e+00	1313.00
IUUC-Pan-091930	Papio anubis	63.91	0.00e+00	1314.00
IUUC-Ppa-095221	Physcomitrella patens	36.89	1.00e-29	124.00
IUUC-Pfo-096884	Poecilia formosa	48.88	0.00e+00	963.00
IUUC-Pab-098404	Pongo abelii	69.44	1.00e-176	615.00
IUUC-Pca-100949	Procavia capensis	49.95	0.00e+00	736.00
IUUC-Ppe-101920	Prunus persica	32.38	5.00e-25	109.00
IUUC-Pva-102634	Pteropus vampyrus	57.46	0.00e+00	1417.00
IUUC-Rno-105870	Rattus norvegicus	56.47	0.00e+00	1414.00
IUUC-Sit-110552	Setaria italica	34.31	2.00e-26	114.00
IUUC-Sly-111158	Solanum lycopersicum	38.32	5.00e-35	143.00
IUUC-Sar-113289	Sorex araneus	62.34	0.00e+00	1112.00
IUUC-Ssc-115509	Sus scrofa	63.05	0.00e+00	1312.00
IUUC-Tca-121624	Theobroma cacao	33.17	3.00e-26	114.00
IUUC-Tae-125629	Triticum aestivum	36.09	3.00e-19	89.70
IUUC-Tbe-127825	Tupaia belangeri	50.28	0.00e+00	826.00
IUUC-Ttr-128754	Tursiops truncatus	60.03	0.00e+00	757.00
IUUC-Vvi-131476	Vitis vinifera	49.37	1.00e-38	155.00
IUUC-Xtr-132838	Xenopus tropicalis	46.89	0.00e+00	1113.00
IUUC-Xma-133119	Xiphophorus maculatus	43.50	0.00e+00	1008.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence