iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093236

Ensembl Protein ID

ENSPSIP00000004186.1

UniProt Accession

K7F826; K7F826_PELSI

Genbank Protein ID

ENSPSIP00000004186

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01144034

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003947.1	ENSPSIT00000004209.1	ENSPSIP00000004186.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.90e-80	268.6	271	766

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+ +l+ + + +n         +l+++lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 271  TGLINLGNTCYMNSVIQALFMATDFRRHVLSLNLNGCN---------SLMRKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 348
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk....eknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvssr 165
           qD++E+l+fll++l+ee       ++ kp e+++++++ ++  e         +   +  ++++li+++F+g+l+++i cl+c+++s++
   Q: 349  QDCSEYLRFLLERLHEEERTlkalSSAKPSENMMNDESLAQ--EtankaqvftEGPCTSGEERTLIEKMFGGKLQTSICCLNCKSTSQK 435
           *****************944555533333333333332222..12344445443344444455************************** PP
   S: 166  eepfldlslpvpgkeetkke..................................................................... 185
           ee f+dlsl++   +  ++                                                                      
   Q: 436  EEAFTDLSLAFCPPSFLENVdmksithssevkddcmvqtsivasspveelaldnslavndgcetvinegilnnitdtdlyqvqdsknms 524
           ***********977754433777889999************************************************************ PP
   S: 186  .........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
                    s++d+L+ f ++e l+g+nkyycekc ++q+aek + + + Pe+Lil L Rfs++ + + r+ki ++v++pl L+l    
   Q: 525  qksvsentpSVTDLLNYFLAPEILNGDNKYYCEKCASLQNAEKIMHIMEEPEYLILTLLRFSYDPKCHIRRKILDNVSLPLILELPVKR 613
           *************************************************************************************9888 PP
   S: 266  tspeekqke................................kkkYeLiavvvHsG.slssGHYvayvkn.................... 301
           t p+ ++ +                                 + Y L++vvvHsG s++sGHY++y++n                    
   Q: 614  TAPSLGVVSrgwsvdiefsdtgenlakklkpsraeevccpeLVPYVLSSVVVHSGvSSESGHYYSYARNitgsgpslglchqsktmala 702
           886655544666666666666677777777777778888889*********************************************99 PP
   S: 302  .......................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                   +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 703  shssflagelshavlendmganeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 766
           999999999999999988887655666*******************999************986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAHFQSQGSQ EPELRLYVSQ VTQVSSLLRS IWKAEPDTLL PSLQELFAVI SSTDTSFEPS 60
VALASLVQHI PLQMITVLIR SLTTDPNVKD ASMTQALCRM IDWLSWPLAQ HVETWVIALL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNGTAGG AAGCTCTCTC TGGCCTTCTG CCAGCAGCTG GTGCGCAGCA TGGCCCACTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	76.34	0.00e+00	1213.00
IUUC-Apl-003435	Anas platyrhynchos	84.06	0.00e+00	1328.00
IUUC-Aca-004556	Anolis carolinensis	79.38	0.00e+00	1222.00
IUUC-Ame-010616	Astyanax mexicanus	62.36	0.00e+00	991.00
IUUC-Bta-013544	Bos taurus	76.78	0.00e+00	1219.00
IUUC-Cja-018745	Callithrix jacchus	74.09	0.00e+00	1188.00
IUUC-Cfa-020434	Canis familiaris	76.82	0.00e+00	1228.00
IUUC-Cpo-021666	Cavia porcellus	76.64	0.00e+00	1183.00
IUUC-Csa-023965	Chlorocebus sabaeus	76.92	0.00e+00	1263.00
IUUC-Cho-024809	Choloepus hoffmanni	70.28	0.00e+00	1020.00
IUUC-Csv-026333	Ciona savignyi	43.50	3.00e-31	127.00
IUUC-Dre-028338	Danio rerio	61.63	0.00e+00	966.00
IUUC-Dno-029372	Dasypus novemcinctus	77.29	0.00e+00	1248.00
IUUC-Dor-030752	Dipodomys ordii	74.19	0.00e+00	1009.00
IUUC-Ete-032588	Echinops telfairi	67.92	0.00e+00	933.00
IUUC-Eca-034416	Equus caballus	77.04	0.00e+00	1258.00
IUUC-Eeu-035132	Erinaceus europaeus	58.92	0.00e+00	880.00
IUUC-Fca-036137	Felis catus	76.40	0.00e+00	1243.00
IUUC-Fal-037297	Ficedula albicollis	84.10	0.00e+00	1350.00
IUUC-Gmo-038727	Gadus morhua	64.22	0.00e+00	778.00
IUUC-Gga-041091	Gallus gallus	81.73	0.00e+00	1280.00
IUUC-Gac-042082	Gasterosteus aculeatus	60.55	0.00e+00	913.00
IUUC-Ggo-045376	Gorilla gorilla	71.43	0.00e+00	1107.00
IUUC-Hsa-046444	Homo sapiens	76.58	0.00e+00	1233.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	76.12	0.00e+00	1238.00
IUUC-Lch-050500	Latimeria chalumnae	69.71	0.00e+00	1135.00
IUUC-Loc-052625	Lepisosteus oculatus	64.47	0.00e+00	1030.00
IUUC-Laf-053689	Loxodonta africana	76.77	0.00e+00	1248.00
IUUC-Mcc-055286	Macaca mulatta	77.15	0.00e+00	1228.00
IUUC-Mga-059905	Meleagris gallopavo	80.95	0.00e+00	1299.00
IUUC-Mmr-061397	Microcebus murinus	77.29	0.00e+00	1240.00
IUUC-Mdo-062833	Monodelphis domestica	80.60	0.00e+00	1347.00
IUUC-Mmu-063157	Mus musculus	75.09	0.00e+00	1217.00
IUUC-Mpu-066434	Mustela putorius furo	76.35	0.00e+00	1241.00
IUUC-Mlu-068178	Myotis lucifugus	75.57	0.00e+00	1186.00
IUUC-Nle-070153	Nomascus leucogenys	76.12	0.00e+00	1191.00
IUUC-Ont-072330	Oreochromis niloticus	60.90	0.00e+00	972.00
IUUC-Oan-072709	Ornithorhynchus anatinus	79.34	0.00e+00	1251.00
IUUC-Ocu-074832	Oryctolagus cuniculus	76.23	0.00e+00	1224.00
IUUC-Ola-087003	Oryzias latipes	54.12	8.00e-44	169.00
IUUC-Oga-088517	Otolemur garnettii	72.32	0.00e+00	1166.00
IUUC-Oar-089472	Ovis aries	72.87	0.00e+00	1144.00
IUUC-Ptr-090996	Pan troglodytes	76.46	0.00e+00	1233.00
IUUC-Pan-091837	Papio anubis	74.94	0.00e+00	1198.00
IUUC-Pfo-097193	Poecilia formosa	60.62	0.00e+00	902.00
IUUC-Pab-098710	Pongo abelii	76.55	0.00e+00	1235.00
IUUC-Pca-100794	Procavia capensis	65.83	0.00e+00	1009.00
IUUC-Pva-102722	Pteropus vampyrus	75.09	0.00e+00	1212.00
IUUC-Rno-105743	Rattus norvegicus	74.63	0.00e+00	1194.00
IUUC-Sha-106563	Sarcophilus harrisii	80.53	0.00e+00	1341.00
IUUC-Sar-113533	Sorex araneus	64.98	0.00e+00	991.00
IUUC-Ssc-116259	Sus scrofa	68.23	0.00e+00	989.00
IUUC-Tgu-117475	Taeniopygia guttata	83.97	0.00e+00	1347.00
IUUC-Tru-118623	Takifugu rubripes	60.85	0.00e+00	898.00
IUUC-Tsy-119250	Tarsius syrichta	76.84	0.00e+00	1190.00
IUUC-Tni-120441	Tetraodon nigroviridis	56.43	0.00e+00	814.00
IUUC-Tbe-127936	Tupaia belangeri	63.95	0.00e+00	942.00
IUUC-Ttr-128483	Tursiops truncatus	63.91	0.00e+00	977.00
IUUC-Vpa-130303	Vicugna pacos	91.94	0.00e+00	685.00
IUUC-Xtr-132773	Xenopus tropicalis	68.15	0.00e+00	1098.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence