iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020529

Ensembl Protein ID

ENSCAFP00000009932.3

UniProt Accession

F1PTL5; F1PTL5_CANLF

Genbank Protein ID

ENSCAFP00000009932

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000996

Gene Name

WDR62

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000006621.3	ENSCAFT00000010711.3	ENSCAFP00000009932.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-26	91.4	153	190
UBD/Beta-Prp	8.40e-55	186.3	495	754

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgv 34
           gH+ +v c+af ++ +++vs +  +D ++ vWD++++ 
   Q: 153  GHKYGVACVAFsPNmKHIVSMGyqHDMVLNVWDWKKDI 190
           89**********888*****9989*********98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgk...ilvtgseDrtikvwdls.tgkcvhtlkghedsv 97
           ++++++spd+++la+g r+g +++++++ ++ l +++ h+aev ++++s+ +    +l+++s+Dr+i+v +++ ++   +tl  h++s+
   Q: 495  VRVMQVSPDGQHLASGDRSGNLRIHELHFMDELVKVEAHDAEVLCLEYSKPETgltLLASASRDRLIHVLNVEkNYNLEQTLDDHSSSI 583
           67899*******************************************99887899**************9997888999********* PP
   S: 98   lslsfspsg.dklvsGshdrtirv.wdletgqcleetlsghdg...vvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltgg 178
           ++++f  ++   ++s ++d+ i      +t   l+ + + h +   +   + ++ ++++++ ++ Dr vr+++    k++k+ +  +g 
   Q: 584  TAIKFAGNRdIQMISCGADKSIYFrSAQRTSDGLHFVRTHHVAektTLYDMDIDITQKYVAVACQDRNVRVYNTvngKQKKCYKGSQG- 671
           *******885789*******9988655555555553333333300023345677788****************988888888888888. PP
   S: 179  htdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW.......dlrsg 254
           +++s  ++ +d++g++l++   d+++ + d+ +gec+ ++ gh++ v+s++f+ +  +l+++s D  ++iW       ++ ++
   Q: 672  DEGSLLKVHVDPSGTFLATSCSDKSISVIDFYSGECIAKMFGHSEIVTSMKFTYDCRHLITVSGDSCVFIWhlgpeitNCMKQ 754
           999999999**************************************************************665555544444 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAALGPGGYA RNDAVEKLPS GAAGVPARRG QCSPPPAPPL CLRRRTRLST APEDTVQNRV 60
SLEKVLGITA QNSSGLTCDP NTGHVAYLAG CVVVILNPKE NKQQHIFNTA RKSLSALAFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCCT TGGGGCCCGG AGGCTACGCG CGCAACGATG CAGTGGAGAA GCTGCCGTCC 60
GGCGCGGCGG GGGTTCCGGC GCGGAGGGGC CAGTGCTCTC CGCCCCCCGC CCCGCCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR030545--WDR62

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005813--C:centrosome
GO:0071011--C:precatalytic spliceosome
GO:0000922--C:spindle pole
GO:0005682--C:U5 snRNP
GO:0007099--P:centriole replication
GO:0021987--P:cerebral cortex development
GO:0007052--P:mitotic spindle organization
GO:0022008--P:neurogenesis
GO:0008380--P:RNA splicing

KEGG

cfa:484565

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001371	Ailuropoda melanoleuca	90.38	0.00e+00	2639.00
IUUC-Aca-004935	Anolis carolinensis	70.70	0.00e+00	1006.00
IUUC-Ath-007624	Arabidopsis thaliana	30.51	2.00e-93	337.00
IUUC-Afu-008757	Aspergillus fumigatus	21.75	2.00e-30	128.00
IUUC-Bta-013336	Bos taurus	81.78	0.00e+00	2311.00
IUUC-Cel-018592	Caenorhabditis elegans	28.74	4.00e-74	273.00
IUUC-Cja-019094	Callithrix jacchus	79.64	0.00e+00	2269.00
IUUC-Cpo-021970	Cavia porcellus	87.89	0.00e+00	1675.00
IUUC-Csa-024161	Chlorocebus sabaeus	80.86	0.00e+00	2278.00
IUUC-Cho-024310	Choloepus hoffmanni	85.43	0.00e+00	1172.00
IUUC-Cin-025412	Ciona intestinalis	52.94	4.00e-59	220.00
IUUC-Cgl-026454	Colletotrichum gloeosporioides	22.42	8.00e-24	106.00
IUUC-Dno-029933	Dasypus novemcinctus	77.72	0.00e+00	2201.00
IUUC-Dor-031147	Dipodomys ordii	77.78	0.00e+00	2138.00
IUUC-Dse-031501	Dothistroma septosporum	30.53	6.00e-23	103.00
IUUC-Eca-033675	Equus caballus	82.96	0.00e+00	2393.00
IUUC-Fca-035826	Felis catus	88.10	0.00e+00	2632.00
IUUC-Gma-043644	Glycine max	31.93	1.00e-102	368.00
IUUC-Ggo-045152	Gorilla gorilla	82.35	0.00e+00	2266.00
IUUC-Hsa-045891	Homo sapiens	82.22	0.00e+00	2300.00
IUUC-Itr-048019	Ictidomys tridecemlineatus	93.24	0.00e+00	1567.00
IUUC-Lch-049669	Latimeria chalumnae	58.52	0.00e+00	1012.00
IUUC-Loc-052488	Lepisosteus oculatus	53.33	0.00e+00	1060.00
IUUC-Laf-053992	Loxodonta africana	79.61	0.00e+00	2286.00
IUUC-Mcc-054994	Macaca mulatta	81.89	0.00e+00	2248.00
IUUC-Meu-056815	Macropus eugenii	79.18	0.00e+00	1431.00
IUUC-Mtr-058383	Medicago truncatula	31.16	4.00e-51	195.00
IUUC-Mmr-060693	Microcebus murinus	79.39	0.00e+00	2221.00
IUUC-Mdo-063007	Monodelphis domestica	61.55	0.00e+00	1791.00
IUUC-Mmu-064067	Mus musculus	75.33	0.00e+00	2155.00
IUUC-Mpu-066532	Mustela putorius furo	89.94	0.00e+00	2691.00
IUUC-Mlu-066982	Myotis lucifugus	80.87	0.00e+00	2268.00
IUUC-Nle-070042	Nomascus leucogenys	86.95	0.00e+00	1917.00
IUUC-Opr-070397	Ochotona princeps	77.52	0.00e+00	2259.00
IUUC-Ocu-074274	Oryctolagus cuniculus	79.82	0.00e+00	2224.00
IUUC-Oga-088577	Otolemur garnettii	81.85	0.00e+00	2350.00
IUUC-Oar-090117	Ovis aries	79.90	0.00e+00	2263.00
IUUC-Ptr-090553	Pan troglodytes	82.15	0.00e+00	2319.00
IUUC-Pan-092559	Papio anubis	72.47	0.00e+00	1077.00
IUUC-Psi-093710	Pelodiscus sinensis	65.19	0.00e+00	1409.00
IUUC-Pno-094837	Phaeosphaeria nodorum	24.78	6.00e-35	143.00
IUUC-Pab-098510	Pongo abelii	81.38	0.00e+00	2215.00
IUUC-Pca-100323	Procavia capensis	71.18	0.00e+00	1330.00
IUUC-Pva-102895	Pteropus vampyrus	85.71	0.00e+00	2462.00
IUUC-Pte-104373	Pyrenophora teres	24.62	9.00e-28	119.00
IUUC-Pyt-104804	Pyrenophora triticirepentis	24.89	1.00e-27	119.00
IUUC-Rno-105598	Rattus norvegicus	75.89	0.00e+00	2179.00
IUUC-Sha-107013	Sarcophilus harrisii	67.02	0.00e+00	1826.00
IUUC-Smo-109134	Selaginella moellendorffii	36.96	1.00e-134	474.00
IUUC-Sar-113261	Sorex araneus	76.83	0.00e+00	2186.00
IUUC-Ssc-115317	Sus scrofa	82.93	0.00e+00	2306.00
IUUC-Tsy-118799	Tarsius syrichta	90.59	0.00e+00	852.00
IUUC-Tni-120316	Tetraodon nigroviridis	56.35	0.00e+00	792.00
IUUC-Tvi-122281	Trichoderma virens	23.26	2.00e-29	124.00
IUUC-Tme-127128	Tuber melanosporum	23.63	7.00e-32	133.00
IUUC-Tbe-127555	Tupaia belangeri	94.15	0.00e+00	1025.00
IUUC-Ttr-128722	Tursiops truncatus	83.20	0.00e+00	2389.00
IUUC-Vda-129957	Verticillium dahliae	23.11	5.00e-31	130.00
IUUC-Vpa-130392	Vicugna pacos	71.92	2.00e-114	406.00
IUUC-Vvi-131035	Vitis vinifera	34.26	5.00e-108	385.00
IUUC-Xtr-131789	Xenopus tropicalis	59.39	0.00e+00	985.00
IUUC-Yli-134437	Yarrowia lipolytica	26.05	4.00e-16	80.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence