iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033388

UUCD1 version

UUC-EqC-00308

Ensembl Protein ID

ENSECAP00000013034.1

UniProt Accession

F6UYJ8; F6UYJ8_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000015363.1	ENSECAT00000016155.1	ENSECAP00000013034.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.60e-19	69.5	51	115
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.80e-08	31.3	150	179

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 51   DVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEME-QEEVLIHGVSYNAMCQILHFIYTSELEL 115
           9***********************************8.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           eN l+++r+A+l+d+++L ++ +++ilk+F
   Q: 150  ENILDVYRLAELFDLSRLTEQLDTYILKNF 179
           8***************************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MAEEQEFTQL CKLPVQPSHP HCVNNTYRSA QHSQALLRGL LALRDSGILF DVVLVVEGRH 60
IEAHRILLAA SCDYFRGMFA GGLKEMEQEE VLIHGVSYNA MCQILHFIYT SELELSLSNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCTGACA GCCGCGGTGG TGAGGTCTGG TGTCGTGGTC AGAATGGCGG AAGAGCAGGA 60
GTTCACTCAG TTGTGCAAGT TGCCTGTGCA GCCCTCACAC CCACACTGCG TCAACAACAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

ecb:100049928

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	98.26	0.00e+00	1242.00
IUUC-Apl-004081	Anas platyrhynchos	77.27	0.00e+00	1022.00
IUUC-Aca-005015	Anolis carolinensis	65.97	0.00e+00	847.00
IUUC-Ame-011712	Astyanax mexicanus	59.53	0.00e+00	721.00
IUUC-Bta-012594	Bos taurus	94.79	0.00e+00	1233.00
IUUC-Cja-019752	Callithrix jacchus	97.43	0.00e+00	1035.00
IUUC-Cfa-020884	Canis familiaris	98.74	0.00e+00	1306.00
IUUC-Cpo-021711	Cavia porcellus	96.69	0.00e+00	1264.00
IUUC-Csa-023211	Chlorocebus sabaeus	98.11	0.00e+00	1297.00
IUUC-Dre-028395	Danio rerio	59.74	0.00e+00	750.00
IUUC-Dno-030096	Dasypus novemcinctus	94.20	0.00e+00	1231.00
IUUC-Dor-030709	Dipodomys ordii	96.22	0.00e+00	709.00
IUUC-Eeu-034616	Erinaceus europaeus	85.33	0.00e+00	1099.00
IUUC-Fca-035815	Felis catus	98.26	0.00e+00	1303.00
IUUC-Fal-037311	Ficedula albicollis	79.51	0.00e+00	1003.00
IUUC-Gmo-039571	Gadus morhua	52.26	3.00e-157	548.00
IUUC-Gga-040992	Gallus gallus	77.12	0.00e+00	1022.00
IUUC-Gac-042041	Gasterosteus aculeatus	55.17	0.00e+00	683.00
IUUC-Ggo-045141	Gorilla gorilla	92.43	0.00e+00	1200.00
IUUC-Hsa-045984	Homo sapiens	98.26	0.00e+00	1300.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	98.11	0.00e+00	1298.00
IUUC-Lch-049700	Latimeria chalumnae	60.97	0.00e+00	732.00
IUUC-Loc-052141	Lepisosteus oculatus	61.04	0.00e+00	806.00
IUUC-Laf-053487	Loxodonta africana	95.40	0.00e+00	1230.00
IUUC-Mcc-054682	Macaca mulatta	97.67	0.00e+00	1022.00
IUUC-Meu-055937	Macropus eugenii	74.29	0.00e+00	964.00
IUUC-Mga-059953	Meleagris gallopavo	77.12	0.00e+00	1022.00
IUUC-Mmr-061743	Microcebus murinus	97.48	0.00e+00	1263.00
IUUC-Mdo-062328	Monodelphis domestica	82.45	0.00e+00	1085.00
IUUC-Mmu-063979	Mus musculus	94.42	0.00e+00	1218.00
IUUC-Mpu-066750	Mustela putorius furo	98.26	0.00e+00	1302.00
IUUC-Mlu-066960	Myotis lucifugus	95.90	0.00e+00	1246.00
IUUC-Nle-069690	Nomascus leucogenys	98.20	0.00e+00	1145.00
IUUC-Opr-071059	Ochotona princeps	90.24	0.00e+00	1152.00
IUUC-Ont-072004	Oreochromis niloticus	57.80	0.00e+00	685.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.25	0.00e+00	740.00
IUUC-Ocu-074310	Oryctolagus cuniculus	97.35	1.00e-157	548.00
IUUC-Ola-086599	Oryzias latipes	57.19	0.00e+00	699.00
IUUC-Oga-087980	Otolemur garnettii	97.95	0.00e+00	1270.00
IUUC-Oar-089956	Ovis aries	79.32	0.00e+00	924.00
IUUC-Ptr-090598	Pan troglodytes	98.39	0.00e+00	1151.00
IUUC-Pan-092387	Papio anubis	97.47	0.00e+00	1022.00
IUUC-Psi-093484	Pelodiscus sinensis	78.68	0.00e+00	1050.00
IUUC-Pma-094224	Petromyzon marinus	49.75	5.00e-172	597.00
IUUC-Pfo-096149	Poecilia formosa	57.80	0.00e+00	713.00
IUUC-Pab-098097	Pongo abelii	98.11	0.00e+00	1300.00
IUUC-Pca-100118	Procavia capensis	95.68	0.00e+00	703.00
IUUC-Pva-103174	Pteropus vampyrus	98.10	2.00e-159	555.00
IUUC-Rno-105350	Rattus norvegicus	94.81	0.00e+00	1206.00
IUUC-Sha-106817	Sarcophilus harrisii	82.40	4.00e-134	471.00
IUUC-Sar-113490	Sorex araneus	96.50	0.00e+00	651.00
IUUC-Ssc-115827	Sus scrofa	95.74	0.00e+00	1253.00
IUUC-Tgu-116748	Taeniopygia guttata	81.75	0.00e+00	898.00
IUUC-Tru-118644	Takifugu rubripes	57.49	0.00e+00	689.00
IUUC-Tsy-118888	Tarsius syrichta	91.40	0.00e+00	1045.00
IUUC-Tni-120060	Tetraodon nigroviridis	54.28	2.00e-175	608.00
IUUC-Ttr-129183	Tursiops truncatus	95.52	0.00e+00	1118.00
IUUC-Xtr-132780	Xenopus tropicalis	68.53	0.00e+00	899.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence