iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cja-019660

Ensembl Protein ID

ENSCJAP00000012500.1

UniProt Accession

F7H848; F7H848_CALJA

Genbank Protein ID

JAB10325.1; JAB40811.1

Protein Name

Coronin

Genbank Nucleotide ID

ACFV01131062; GAMQ01001040

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000006672.1	ENSCJAT00000013177.1	ENSCJAP00000012500.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-20	72.5	79	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           gHt++v ++ +   +d+ ++sGs D+t++vW++ +g l
   Q: 79   GHTAPVLDITWcphNDNVIASGSEDCTVMVWEIPDGGL 116
           8***********9877****************998875 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI CEASGGGAFL 60
VLPLAKTGRV DKNVPMVCGH TAPVLDITWC PHNDNVIASG SEDCTVMVWE IPDGGLTLPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTTCTCA TTCATTGTCT TGACAAGAGC ATCCTCAGCG GGCGAGTCCC CGGCTCCTCC 60
AGCTCCTTCC TCCTTCTCCT CCTCCACCTC CGGCTTCTGG GGGTCACTGT CCTCTCTTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR015049--Trimer_CC
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF08954--Trimer_CC
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0003723--F:RNA binding
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

KEGG

cjc:100392238

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002012	Ailuropoda melanoleuca	96.96	0.00e+00	927.00
IUUC-Aca-005048	Anolis carolinensis	66.39	0.00e+00	676.00
IUUC-Ame-011101	Astyanax mexicanus	69.08	0.00e+00	687.00
IUUC-Bgr-011990	Blumeria graminis	42.12	2.00e-98	352.00
IUUC-Bta-013168	Bos taurus	96.10	0.00e+00	924.00
IUUC-Cfa-020938	Canis familiaris	96.96	0.00e+00	927.00
IUUC-Cpo-022056	Cavia porcellus	95.66	0.00e+00	924.00
IUUC-Csa-023193	Chlorocebus sabaeus	98.26	0.00e+00	936.00
IUUC-Cne-026773	Cryptococcus neoformans	38.70	6.00e-87	315.00
IUUC-Dre-028167	Danio rerio	68.64	0.00e+00	674.00
IUUC-Dno-029363	Dasypus novemcinctus	96.75	0.00e+00	924.00
IUUC-Dor-030426	Dipodomys ordii	96.31	0.00e+00	922.00
IUUC-Eca-034229	Equus caballus	95.66	0.00e+00	916.00
IUUC-Eeu-034499	Erinaceus europaeus	93.83	0.00e+00	786.00
IUUC-Fca-036472	Felis catus	95.66	0.00e+00	918.00
IUUC-Gmo-039519	Gadus morhua	66.09	0.00e+00	656.00
IUUC-Gac-042545	Gasterosteus aculeatus	68.34	0.00e+00	682.00
IUUC-Ggo-045162	Gorilla gorilla	98.05	0.00e+00	936.00
IUUC-Hsa-046874	Homo sapiens	98.05	0.00e+00	936.00
IUUC-Itr-048911	Ictidomys tridecemlineatus	96.53	0.00e+00	927.00
IUUC-Lch-050582	Latimeria chalumnae	66.95	0.00e+00	693.00
IUUC-Laf-053427	Loxodonta africana	96.53	0.00e+00	917.00
IUUC-Mcc-055750	Macaca mulatta	98.13	0.00e+00	869.00
IUUC-Meu-056083	Macropus eugenii	88.50	0.00e+00	854.00
IUUC-Mla-058883	Melampsora laricipopulina	43.32	2.00e-87	316.00
IUUC-Mvi-060569	Microbotryum violaceum	40.49	2.00e-88	319.00
IUUC-Mmr-060858	Microcebus murinus	96.96	0.00e+00	928.00
IUUC-Mdo-062469	Monodelphis domestica	90.39	0.00e+00	862.00
IUUC-Mmu-063583	Mus musculus	94.79	0.00e+00	914.00
IUUC-Mpu-066451	Mustela putorius furo	96.83	0.00e+00	892.00
IUUC-Mlu-066978	Myotis lucifugus	95.44	0.00e+00	915.00
IUUC-Ncr-068781	Neurospora crassa	40.27	2.00e-98	353.00
IUUC-Nle-069815	Nomascus leucogenys	98.26	0.00e+00	935.00
IUUC-Opr-070911	Ochotona princeps	93.28	0.00e+00	892.00
IUUC-Ont-072391	Oreochromis niloticus	68.61	0.00e+00	686.00
IUUC-Ocu-074429	Oryctolagus cuniculus	85.47	0.00e+00	791.00
IUUC-Oga-089072	Otolemur garnettii	95.03	0.00e+00	911.00
IUUC-Oar-089676	Ovis aries	96.31	0.00e+00	926.00
IUUC-Ptr-091647	Pan troglodytes	98.05	0.00e+00	936.00
IUUC-Pan-092672	Papio anubis	98.26	0.00e+00	936.00
IUUC-Pab-098348	Pongo abelii	92.62	0.00e+00	866.00
IUUC-Pva-102668	Pteropus vampyrus	96.10	0.00e+00	921.00
IUUC-Pgr-103354	Puccinia graminis	42.22	1.00e-92	333.00
IUUC-Ptt-103735	Puccinia triticina	35.02	3.00e-71	262.00
IUUC-Rno-105604	Rattus norvegicus	94.14	0.00e+00	905.00
IUUC-Sha-107210	Sarcophilus harrisii	89.80	0.00e+00	879.00
IUUC-Sar-113292	Sorex araneus	95.95	0.00e+00	738.00
IUUC-Sre-114911	Sporisorium reilianum	39.28	1.00e-80	293.00
IUUC-Tme-126924	Tuber melanosporum	41.22	4.00e-94	338.00
IUUC-Tbe-128025	Tupaia belangeri	95.91	8.00e-153	532.00
IUUC-Ttr-128689	Tursiops truncatus	96.10	0.00e+00	922.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence