iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-034229

Ensembl Protein ID

ENSECAP00000022406.1

UniProt Accession

F6Q6X3; F6Q6X3_HORSE

Protein Name

Coronin

Gene Name

CORO1A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024788.1	ENSECAT00000026814.1	ENSECAP00000022406.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-20	71.7	79	116

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           gHt++v ++a+   +d+ ++sGs D+t++vW++ +g l
   Q: 79   GHTAPVLDIAWcphNDNVIASGSEDCTVMVWEIPDGGL 116
           8***********9877****************998865 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSRQVVRSSK FRHVFGQPAK ADQCYEDVRV SQTTWDSGFC AVNPKFVALI CEASGGGAFL 60
VLPLGKTGRV DKNAPTVCGH TAPVLDIAWC PHNDNVIASG SEDCTVMVWE IPDGGLVLPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTGTCTTGAC AAGAGCATCC TCAGCGGGCA GTCTCTGGCT CCTCCAGCTC CTTCCTTATC 60
CTTCTGCTCT CCCTCCTCCA TTTGGGGGTC ACTCATCTCA GCAGCAGGTA AGCCTGGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR029508--CORO1A
IPR015505--Coronin
IPR015048--DUF1899
IPR015049--Trimer_CC
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08953--DUF1899
PF08954--Trimer_CC
PF00400--WD40

SMART

SM01166--DUF1899
SM00320--WD40

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005884--C:actin filament
GO:0030424--C:axon
GO:0005911--C:cell-cell junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0001772--C:immunological synapse
GO:0030027--C:lamellipodium
GO:0001891--C:phagocytic cup
GO:0045335--C:phagocytic vesicle
GO:0043234--C:protein complex
GO:0051015--F:actin filament binding
GO:0003723--F:RNA binding
GO:0030036--P:actin cytoskeleton organization
GO:0007015--P:actin filament organization
GO:0006816--P:calcium ion transport
GO:0031589--P:cell-substrate adhesion
GO:0071353--P:cellular response to interleukin-4
GO:0061502--P:early endosome to recycling endosome transport
GO:0048873--P:homeostasis of number of cells within a tissue
GO:0030595--P:leukocyte chemotaxis
GO:0043320--P:natural killer cell degranulation
GO:0051126--P:negative regulation of actin nucleation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0031339--P:negative regulation of vesicle fusion
GO:0038180--P:nerve growth factor signaling pathway
GO:0001845--P:phagolysosome assembly
GO:0050918--P:positive chemotaxis
GO:0030335--P:positive regulation of cell migration
GO:0042102--P:positive regulation of T cell proliferation
GO:0008360--P:regulation of cell shape
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0043029--P:T cell homeostasis
GO:0032796--P:uropod organization

KEGG

ecb:100064170

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002012	Ailuropoda melanoleuca	96.75	0.00e+00	925.00
IUUC-Aca-005048	Anolis carolinensis	65.97	0.00e+00	671.00
IUUC-Ame-011101	Astyanax mexicanus	67.98	0.00e+00	678.00
IUUC-Bta-013168	Bos taurus	95.44	0.00e+00	920.00
IUUC-Cja-019660	Callithrix jacchus	95.66	0.00e+00	916.00
IUUC-Cfa-020938	Canis familiaris	96.96	0.00e+00	929.00
IUUC-Cpo-022056	Cavia porcellus	93.71	0.00e+00	903.00
IUUC-Csa-023193	Chlorocebus sabaeus	96.53	0.00e+00	920.00
IUUC-Dno-029363	Dasypus novemcinctus	95.66	0.00e+00	914.00
IUUC-Dor-030426	Dipodomys ordii	94.14	0.00e+00	900.00
IUUC-Eeu-034499	Erinaceus europaeus	94.81	0.00e+00	793.00
IUUC-Fca-036472	Felis catus	95.44	0.00e+00	915.00
IUUC-Gmo-039519	Gadus morhua	66.09	0.00e+00	653.00
IUUC-Gac-042545	Gasterosteus aculeatus	67.90	0.00e+00	676.00
IUUC-Ggo-045162	Gorilla gorilla	96.53	0.00e+00	922.00
IUUC-Hsa-046874	Homo sapiens	96.53	0.00e+00	922.00
IUUC-Itr-048911	Ictidomys tridecemlineatus	94.79	0.00e+00	912.00
IUUC-Lch-050582	Latimeria chalumnae	65.89	0.00e+00	683.00
IUUC-Laf-053427	Loxodonta africana	95.66	0.00e+00	905.00
IUUC-Mcc-055750	Macaca mulatta	96.25	0.00e+00	855.00
IUUC-Meu-056083	Macropus eugenii	87.42	0.00e+00	843.00
IUUC-Mmr-060858	Microcebus murinus	96.10	0.00e+00	920.00
IUUC-Mdo-062469	Monodelphis domestica	89.52	0.00e+00	851.00
IUUC-Mmu-063583	Mus musculus	93.28	0.00e+00	898.00
IUUC-Mpu-066451	Mustela putorius furo	96.61	0.00e+00	890.00
IUUC-Mlu-066978	Myotis lucifugus	96.10	0.00e+00	920.00
IUUC-Nle-069815	Nomascus leucogenys	96.31	0.00e+00	920.00
IUUC-Opr-070911	Ochotona princeps	93.28	0.00e+00	889.00
IUUC-Ont-072391	Oreochromis niloticus	67.97	0.00e+00	680.00
IUUC-Ocu-074429	Oryctolagus cuniculus	84.60	0.00e+00	779.00
IUUC-Oga-089072	Otolemur garnettii	95.03	0.00e+00	909.00
IUUC-Oar-089676	Ovis aries	95.66	0.00e+00	922.00
IUUC-Ptr-091647	Pan troglodytes	96.75	0.00e+00	924.00
IUUC-Pan-092672	Papio anubis	96.53	0.00e+00	920.00
IUUC-Pab-098348	Pongo abelii	91.11	0.00e+00	853.00
IUUC-Pva-102668	Pteropus vampyrus	95.88	0.00e+00	920.00
IUUC-Rno-105604	Rattus norvegicus	92.62	0.00e+00	889.00
IUUC-Sha-107210	Sarcophilus harrisii	89.15	0.00e+00	873.00
IUUC-Sar-113292	Sorex araneus	94.86	0.00e+00	731.00
IUUC-Tme-126924	Tuber melanosporum	41.85	1.00e-93	337.00
IUUC-Tbe-128025	Tupaia belangeri	94.05	3.00e-149	520.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence