iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mlu-067010

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02010194

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000005462.2	ENSMLUT00000005465.2	ENSMLUP00000004985.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.10e-59	200.2	56	370

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl+N+g tC +NS++Q+L++   +++ l++    +++++  +e+  ++  +l  l+e++++s++kav p el+ +l+k+++    + q
   Q: 56   VGLHNIGQTCCLNSLIQVLIMNMGFTQILKR---VTVPRRV-EEQRRNVPFQLLLLLEKMQDSRQKAVRPMELVYCLQKYNVP--LFVQ 138
           6******************************...4444443.466779*********************************99..79** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da  +   + + ++ ++                          ++    + ++ l+ +++k++ +clec  +ssr++++l+l+l++ +
   Q: 139  HDAAQLYFTIWNLIKGQI--------------------------TDVDLVERLQALYTIRMKESFICLECTIESSRNSSMLTLPLSLFD 201
           ******************..........................66778899************************************9 PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +++ +++++d+L+ f+++ el +++k++ce+c kk+  ++ lkl++lP++L++hL+Rfs +  +++ eki  +++fp++Ldl++f+ +
   Q: 202  MDSKPLKTVEDALHCFFQPRELSNKDKCFCENCGKKTHGKQVLKLTHLPQTLTIHLMRFSIR--NSRTEKICHSLYFPQSLDLNQFLLT 288
           99999******************************************************665..57999****************9888 PP
   S: 268  peekqke....kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetg.......staYvlfYkr 337
           +++  +     +  YeL+av+ H G ++ GHY+ay++n  +gkW++f+Ds+V  v++e+++ + g       +taY+l+Y++
   Q: 289  DKDLCNAeyqlEGLYELFAVIAHVGLPDFGHYCAYIRNsVDGKWFCFNDSSVCWVSWEDIQCTYGnhncrwrETAYLLVYMK 370
           5555544677799*************************45677*******************888***************98 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

NGQGVWVPKE ICQSVLAESQ HFSADPVEKK QENSNMKKRE QLPKYSDAWN CPQGPVGLHN 60
IGQTCCLNSL IQVLIMNMGF TQILKRVTVP RRVEEQRRNV PFQLLLLLEK MQDSRQKAVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGGGCAAG GTGTTTGGGT TCCTAAAGAA ATTTGCCAAT CAGTCCTGGC TGAGTCTCAA 60
CATTTCTCAG CAGACCCTGT TGAGAAGAAG CAAGAGAACA GCAACATGAA GAAGAGGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0019785--F:ISG15-specific protease activity
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0035634--P:response to stilbenoid
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001615	Ailuropoda melanoleuca	81.34	1.00e-172	598.00
IUUC-Apl-004006	Anas platyrhynchos	55.00	5.00e-102	363.00
IUUC-Aca-005088	Anolis carolinensis	54.40	1.00e-90	326.00
IUUC-Ame-010606	Astyanax mexicanus	33.44	9.00e-42	163.00
IUUC-Bta-013036	Bos taurus	79.38	1.00e-154	538.00
IUUC-Cja-019052	Callithrix jacchus	73.91	8.00e-141	493.00
IUUC-Cfa-020554	Canis familiaris	83.09	5.00e-171	593.00
IUUC-Cpo-022421	Cavia porcellus	71.66	1.00e-156	545.00
IUUC-Csa-023737	Chlorocebus sabaeus	77.23	1.00e-93	335.00
IUUC-Cho-024807	Choloepus hoffmanni	70.05	6.00e-71	261.00
IUUC-Dre-027408	Danio rerio	32.11	9.00e-44	170.00
IUUC-Dno-029813	Dasypus novemcinctus	66.22	2.00e-123	435.00
IUUC-Dor-030532	Dipodomys ordii	70.68	5.00e-153	533.00
IUUC-Ete-032254	Echinops telfairi	68.03	9.00e-150	523.00
IUUC-Eca-033482	Equus caballus	84.06	5.00e-163	566.00
IUUC-Eeu-034451	Erinaceus europaeus	76.42	1.00e-97	348.00
IUUC-Fca-036313	Felis catus	81.72	5.00e-179	620.00
IUUC-Fal-037216	Ficedula albicollis	50.28	2.00e-99	355.00
IUUC-Gmo-038649	Gadus morhua	32.81	3.00e-39	155.00
IUUC-Gga-041082	Gallus gallus	52.87	2.00e-91	329.00
IUUC-Gac-042439	Gasterosteus aculeatus	36.05	4.00e-48	185.00
IUUC-Ggo-044957	Gorilla gorilla	80.81	5.00e-133	466.00
IUUC-Hsa-046381	Homo sapiens	77.47	6.00e-169	586.00
IUUC-Itr-047918	Ictidomys tridecemlineatus	75.89	1.00e-165	575.00
IUUC-Loc-052688	Lepisosteus oculatus	33.54	6.00e-46	177.00
IUUC-Laf-054109	Loxodonta africana	75.60	2.00e-170	591.00
IUUC-Mcc-054814	Macaca mulatta	74.46	2.00e-168	584.00
IUUC-Meu-056253	Macropus eugenii	67.01	7.00e-110	389.00
IUUC-Mmr-061613	Microcebus murinus	75.96	4.00e-154	537.00
IUUC-Mdo-061890	Monodelphis domestica	62.72	1.00e-122	432.00
IUUC-Mmu-064329	Mus musculus	69.71	1.00e-145	509.00
IUUC-Mpu-066342	Mustela putorius furo	80.70	6.00e-178	616.00
IUUC-Nle-069148	Nomascus leucogenys	75.55	2.00e-163	568.00
IUUC-Opr-070988	Ochotona princeps	68.15	8.00e-63	234.00
IUUC-Ont-072039	Oreochromis niloticus	34.06	6.00e-45	174.00
IUUC-Oan-073740	Ornithorhynchus anatinus	56.79	1.00e-73	269.00
IUUC-Ocu-074498	Oryctolagus cuniculus	76.45	9.00e-151	526.00
IUUC-Ola-086753	Oryzias latipes	35.13	1.00e-47	183.00
IUUC-Oga-088497	Otolemur garnettii	74.64	3.00e-158	551.00
IUUC-Oar-089505	Ovis aries	78.75	8.00e-154	535.00
IUUC-Ptr-091656	Pan troglodytes	77.20	3.00e-169	587.00
IUUC-Pan-092498	Papio anubis	74.46	6.00e-168	583.00
IUUC-Psi-093409	Pelodiscus sinensis	51.27	3.00e-102	365.00
IUUC-Pfo-096507	Poecilia formosa	35.35	3.00e-47	181.00
IUUC-Pab-097828	Pongo abelii	79.81	1.00e-154	539.00
IUUC-Pca-100299	Procavia capensis	72.22	5.00e-98	350.00
IUUC-Pva-102972	Pteropus vampyrus	83.47	5.00e-176	610.00
IUUC-Rno-105738	Rattus norvegicus	67.83	7.00e-147	513.00
IUUC-Sha-107309	Sarcophilus harrisii	61.56	3.00e-114	404.00
IUUC-Sar-112983	Sorex araneus	67.13	2.00e-130	458.00
IUUC-Ssc-116049	Sus scrofa	82.81	2.00e-162	564.00
IUUC-Tgu-117115	Taeniopygia guttata	55.35	6.00e-100	357.00
IUUC-Tru-118022	Takifugu rubripes	30.53	5.00e-36	144.00
IUUC-Tsy-118986	Tarsius syrichta	63.33	1.00e-63	236.00
IUUC-Tni-120306	Tetraodon nigroviridis	31.53	3.00e-38	152.00
IUUC-Tbe-127768	Tupaia belangeri	67.00	2.00e-111	395.00
IUUC-Ttr-128686	Tursiops truncatus	73.41	4.00e-154	537.00
IUUC-Xtr-132032	Xenopus tropicalis	43.30	7.00e-69	253.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence