iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090016

Ensembl Protein ID

ENSOARP00000017659.1

UniProt Accession

W5Q4L9; W5Q4L9_SHEEP

Genbank Protein ID

ENSOARP00000017659

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01068841

Gene Name

USP31

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000016442.1	ENSOART00000017909.1	ENSOARP00000017659.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-93	313.8	46	683

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp.........kepkgellkslqklfeelwkskkkavspr 71
           Gl+N+gNtC+mN++LQcLsn++ ++e+l            +         p          + +ge++++l++l+++lw+ + +    r
   Q: 46   GLRNHGNTCFMNATLQCLSNTELFAEYLALgqyragrpepS---------PdpeqpagrgAQGQGEVTEQLAHLVRALWTLEYTPQHSR 125
           9***************************9954444333330.........133334444456666************************ PP
   S: 72   ellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecd 160
           +++++++k a +++g++q+DaqEfl +lld+++e+l++ + k+  +   +  se++++ e       ++++++lFq q++s+++c++c+
   Q: 126  DFKSIVSKNALQYRGNSQHDAQEFLLWLLDRVHEDLNH-AVKQSGQPPLKPPSETDMMPEGPSFPVCSTFVQELFQAQYRSSLTCPHCQ 213
           ************************************66.33333344444445666677777888889********************* PP
   S: 161  nvssreepfldlslpvpgkeetkke................................................................ 185
           ++s++++pfl +slp+p  +++ ++                                                                
   Q: 214  KQSNTFDPFLCISLPIPLPHTR-PLyvtvvyqgkcshcmrvgvavplsgtvarlreavsmetkiptdqivltemyydgfhrsfcdtddl 301
           *****************87755.34689************************************************************* PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 302  etvhesdcifafetpeifrpegilsqrgihlnnnlnhlkfgldhyrlsstqaaakqgkadlplsragsdkivllvcnractgqqgkrfg 390
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 391  lpfvlhlektiawdllqkeilekmkyflrptvciqvcpfslrvvsvvgityllpqeeqplchptveralkscgpggtahvklvvewdke 479
           ***************************************************************************************** PP
   S: 186  .................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfse 241
                                            +l++c++ +tkee+l  ++++ c++ck++q+ + +l+l++lP+vLi+hLkRf+ ++
   Q: 480  tkdflfvntedeyipdaesvrlqkerhhqpqtcTLSQCFQLYTKEERLAPDDAWRCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQQQ 568
           ***************************************************************************************** PP
   S: 242  eqksrekinkkvefple.Ldlspfctspeekqke...................kkkYeLiavvvHsGslssGHYvayvknekgk.Wllf 309
           e+++r k+++ v+fpl+ Ld++p+++++++++ +                   +++Y+L+av++H+G++++GHY+a++kn+ ++ W++f
   Q: 569  EGDKRMKLQNMVKFPLTgLDMTPHVVKRSQSSWSlpshwspwrrpyglgrdpeDYIYDLYAVCNHHGTMQGGHYTAFCKNSVDGlWYCF 657
           **************************977666559999999999999999999***************************87777**** PP
   S: 310  dDskVtevkeeevleetgstaYvlfYkrr 338
           dDs V++++e+ev++   + aY+lfY+rr
   Q: 658  DDSDVQQLSEDEVCT---QMAYILFYQRR 683
           ***************...*********96 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

TQLGGSRAPP PAQPAAAVCP PATIPPPPPP PPPPACAAEP VPGVAGLRNH GNTCFMNATL 60
QCLSNTELFA EYLALGQYRA GRPEPSPDPE QPAGRGAQGQ GEVTEQLAHL VRALWTLEYT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCAGCTGG GCGGATCTCG CGCGCCCCCG CCCGCCCAGC CGGCCGCGGC TGGCTAGCTG 60
GCTTGNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001207	Ailuropoda melanoleuca	92.59	0.00e+00	1939.00
IUUC-Apl-003186	Anas platyrhynchos	76.35	0.00e+00	1439.00
IUUC-Aca-004949	Anolis carolinensis	68.66	0.00e+00	1393.00
IUUC-Ame-010968	Astyanax mexicanus	68.47	0.00e+00	1082.00
IUUC-Bta-013271	Bos taurus	97.47	0.00e+00	2008.00
IUUC-Cja-019663	Callithrix jacchus	91.43	0.00e+00	1695.00
IUUC-Cfa-021258	Canis familiaris	93.14	0.00e+00	1962.00
IUUC-Csa-024188	Chlorocebus sabaeus	94.81	0.00e+00	1568.00
IUUC-Cho-024813	Choloepus hoffmanni	84.05	0.00e+00	1531.00
IUUC-Csv-026086	Ciona savignyi	38.90	2.00e-133	469.00
IUUC-Dre-027372	Danio rerio	69.16	0.00e+00	1008.00
IUUC-Dno-029964	Dasypus novemcinctus	85.91	0.00e+00	1774.00
IUUC-Dor-030448	Dipodomys ordii	82.43	0.00e+00	1125.00
IUUC-Ete-032975	Echinops telfairi	75.42	0.00e+00	1420.00
IUUC-Eca-034030	Equus caballus	92.19	0.00e+00	1867.00
IUUC-Eeu-034629	Erinaceus europaeus	84.00	0.00e+00	636.00
IUUC-Fca-035788	Felis catus	95.26	0.00e+00	1586.00
IUUC-Fal-036874	Ficedula albicollis	74.43	0.00e+00	1374.00
IUUC-Gmo-039479	Gadus morhua	58.12	0.00e+00	1167.00
IUUC-Gga-041092	Gallus gallus	75.79	0.00e+00	1526.00
IUUC-Gac-041609	Gasterosteus aculeatus	73.37	0.00e+00	1127.00
IUUC-Ggo-044782	Gorilla gorilla	96.79	0.00e+00	719.00
IUUC-Hsa-046805	Homo sapiens	92.74	0.00e+00	1910.00
IUUC-Itr-048158	Ictidomys tridecemlineatus	91.51	0.00e+00	1749.00
IUUC-Lch-050332	Latimeria chalumnae	65.95	0.00e+00	1316.00
IUUC-Loc-051953	Lepisosteus oculatus	71.51	0.00e+00	1175.00
IUUC-Mcc-055398	Macaca mulatta	92.26	0.00e+00	1916.00
IUUC-Meu-056822	Macropus eugenii	76.86	0.00e+00	1461.00
IUUC-Mga-060115	Meleagris gallopavo	74.02	0.00e+00	1422.00
IUUC-Mmr-061150	Microcebus murinus	92.64	0.00e+00	1854.00
IUUC-Mdo-062700	Monodelphis domestica	83.57	0.00e+00	1800.00
IUUC-Mmu-063512	Mus musculus	89.27	0.00e+00	1783.00
IUUC-Mpu-066059	Mustela putorius furo	92.45	0.00e+00	1401.00
IUUC-Mlu-067870	Myotis lucifugus	86.73	0.00e+00	1725.00
IUUC-Nle-069898	Nomascus leucogenys	92.66	0.00e+00	1880.00
IUUC-Opr-070338	Ochotona princeps	81.80	0.00e+00	889.00
IUUC-Ont-072469	Oreochromis niloticus	67.89	0.00e+00	1116.00
IUUC-Oan-073175	Ornithorhynchus anatinus	77.86	0.00e+00	1518.00
IUUC-Ola-087303	Oryzias latipes	73.31	0.00e+00	1091.00
IUUC-Oga-089021	Otolemur garnettii	92.19	0.00e+00	1867.00
IUUC-Ptr-090864	Pan troglodytes	92.99	0.00e+00	1914.00
IUUC-Pan-092370	Papio anubis	92.36	0.00e+00	1832.00
IUUC-Psi-093881	Pelodiscus sinensis	75.52	0.00e+00	1468.00
IUUC-Pfo-097427	Poecilia formosa	72.28	0.00e+00	1119.00
IUUC-Pab-098104	Pongo abelii	89.80	0.00e+00	1806.00
IUUC-Pca-100640	Procavia capensis	97.27	5.00e-130	459.00
IUUC-Pva-102287	Pteropus vampyrus	82.21	0.00e+00	1521.00
IUUC-Rno-106033	Rattus norvegicus	89.24	0.00e+00	1771.00
IUUC-Sha-107041	Sarcophilus harrisii	83.94	0.00e+00	1655.00
IUUC-Ssc-116412	Sus scrofa	84.80	0.00e+00	779.00
IUUC-Tgu-116889	Taeniopygia guttata	75.15	0.00e+00	1436.00
IUUC-Tru-118340	Takifugu rubripes	73.03	0.00e+00	1114.00
IUUC-Tsy-118887	Tarsius syrichta	86.70	0.00e+00	1650.00
IUUC-Tni-120463	Tetraodon nigroviridis	73.16	0.00e+00	1118.00
IUUC-Tbe-127491	Tupaia belangeri	91.28	1.00e-125	444.00
IUUC-Ttr-128210	Tursiops truncatus	89.09	0.00e+00	1824.00
IUUC-Vpa-130222	Vicugna pacos	83.23	0.00e+00	810.00
IUUC-Xtr-132509	Xenopus tropicalis	63.04	0.00e+00	1313.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence