iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037059

Ensembl Protein ID

ENSFALP00000002742.1

UniProt Accession

U3JIY8; U3JIY8_FICAL

Genbank Protein ID

ENSFALP00000002742

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021290

Gene Name

KLHL12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000002634.1	ENSFALT00000002754.1	ENSFALP00000002742.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.80e-20	70.4	43	106
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	7.20e-14	50.7	142	173

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +Dv+l v+ + f+ah+ivLaa+S++F a+f++el+e++ k++v+i+++ ++ ++ ll+F+Yt ++
   Q: 43   CDVTLRVEHKDFPAHRIVLAACSDYFCAMFTSELSEKD-KPCVDIQGLTASTMEILLDFVYTETV 106
           9************************************9.***********************987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fA++++c dL++aa+ f +khF+
   Q: 142  PSNCLGIRDFAETHNCVDLMQAAEVFSQKHFP 173
           89*****************************6 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MWPCWLCPQV PRAMAPPKDI MTNSHAKSIL NAMNALRKSN TLCDVTLRVE HKDFPAHRIV 60
LAACSDYFCA MFTSELSEKD KPCVDIQGLT ASTMEILLDF VYTETVHVTV ENVQELLPAA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC TGTCGGCGGC GGGCGCCGTG 60
CCATGTGGCC GTGCTGGCTG TGCCCGCAGG TGCCGCGCGC CATGGCCCCC CCCAAGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0030134--C:ER to Golgi transport vesicle
GO:0000139--C:Golgi membrane
GO:0005815--C:microtubule organizing center
GO:0048208--P:COPII vesicle coating
GO:0006513--P:protein monoubiquitination
GO:0016055--P:Wnt signaling pathway

KEGG

fab:101820176

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002301	Ailuropoda melanoleuca	95.89	0.00e+00	1092.00
IUUC-Apl-003339	Anas platyrhynchos	99.61	0.00e+00	1046.00
IUUC-Aca-004418	Anolis carolinensis	98.40	0.00e+00	1122.00
IUUC-Ath-007066	Arabidopsis thaliana	33.33	9.00e-41	161.00
IUUC-Ame-011906	Astyanax mexicanus	75.70	0.00e+00	871.00
IUUC-Bta-012979	Bos taurus	94.00	0.00e+00	1092.00
IUUC-Cja-019582	Callithrix jacchus	96.26	0.00e+00	1105.00
IUUC-Cfa-020716	Canis familiaris	93.97	0.00e+00	1109.00
IUUC-Cpo-022013	Cavia porcellus	95.94	0.00e+00	1110.00
IUUC-Csa-023424	Chlorocebus sabaeus	95.81	0.00e+00	1027.00
IUUC-Cho-024586	Choloepus hoffmanni	79.00	0.00e+00	870.00
IUUC-Dre-028344	Danio rerio	88.93	2.00e-164	571.00
IUUC-Dno-028854	Dasypus novemcinctus	95.76	0.00e+00	1108.00
IUUC-Dor-030403	Dipodomys ordii	95.58	0.00e+00	1104.00
IUUC-Ete-032963	Echinops telfairi	94.83	0.00e+00	964.00
IUUC-Eca-033282	Equus caballus	95.58	0.00e+00	1108.00
IUUC-Eeu-034933	Erinaceus europaeus	96.08	6.00e-140	490.00
IUUC-Fca-035487	Felis catus	95.76	0.00e+00	1108.00
IUUC-Gmo-039564	Gadus morhua	89.68	0.00e+00	1071.00
IUUC-Gga-040629	Gallus gallus	99.65	0.00e+00	1142.00
IUUC-Gac-042526	Gasterosteus aculeatus	89.26	0.00e+00	1070.00
IUUC-Ggo-044839	Gorilla gorilla	95.76	0.00e+00	1107.00
IUUC-Hsa-046742	Homo sapiens	95.76	0.00e+00	1107.00
IUUC-Itr-048958	Ictidomys tridecemlineatus	95.58	0.00e+00	1105.00
IUUC-Lch-049540	Latimeria chalumnae	93.06	0.00e+00	1107.00
IUUC-Loc-051923	Lepisosteus oculatus	93.13	0.00e+00	1083.00
IUUC-Laf-054370	Loxodonta africana	95.58	0.00e+00	1106.00
IUUC-Mcc-054852	Macaca mulatta	95.76	0.00e+00	1107.00
IUUC-Mor-057181	Magnaporthe oryzae	28.39	2.00e-11	63.20
IUUC-Mga-059486	Meleagris gallopavo	98.04	0.00e+00	1035.00
IUUC-Mmr-061777	Microcebus murinus	93.66	0.00e+00	1108.00
IUUC-Mdo-061990	Monodelphis domestica	96.09	0.00e+00	1103.00
IUUC-Mmu-064053	Mus musculus	95.23	0.00e+00	1105.00
IUUC-Mpu-066623	Mustela putorius furo	82.53	0.00e+00	781.00
IUUC-Mlu-067648	Myotis lucifugus	93.28	0.00e+00	1129.00
IUUC-Nle-069714	Nomascus leucogenys	95.58	0.00e+00	1106.00
IUUC-Opr-071143	Ochotona princeps	89.58	0.00e+00	1013.00
IUUC-Ont-071848	Oreochromis niloticus	90.57	0.00e+00	1080.00
IUUC-Oan-073041	Ornithorhynchus anatinus	93.57	1.00e-155	541.00
IUUC-Ocu-074379	Oryctolagus cuniculus	93.79	0.00e+00	1108.00
IUUC-Oin-079973	Oryza indica	32.48	1.00e-34	141.00
IUUC-Ola-087469	Oryzias latipes	90.21	0.00e+00	1077.00
IUUC-Oar-090144	Ovis aries	95.06	0.00e+00	1103.00
IUUC-Ptr-091406	Pan troglodytes	95.76	0.00e+00	1107.00
IUUC-Pan-092762	Papio anubis	94.71	0.00e+00	1089.00
IUUC-Psi-093391	Pelodiscus sinensis	98.22	0.00e+00	1121.00
IUUC-Pma-094134	Petromyzon marinus	75.09	0.00e+00	839.00
IUUC-Pfo-096404	Poecilia formosa	90.39	0.00e+00	1075.00
IUUC-Pab-098425	Pongo abelii	94.88	0.00e+00	1095.00
IUUC-Pca-101093	Procavia capensis	96.21	1.00e-166	579.00
IUUC-Pva-102239	Pteropus vampyrus	85.34	0.00e+00	988.00
IUUC-Rno-104921	Rattus norvegicus	95.41	0.00e+00	1108.00
IUUC-Sha-106625	Sarcophilus harrisii	94.48	0.00e+00	1113.00
IUUC-Sar-113468	Sorex araneus	83.50	0.00e+00	683.00
IUUC-Ssc-116106	Sus scrofa	93.62	0.00e+00	1105.00
IUUC-Tgu-117402	Taeniopygia guttata	76.65	0.00e+00	770.00
IUUC-Tru-117546	Takifugu rubripes	89.68	0.00e+00	1071.00
IUUC-Tsy-118802	Tarsius syrichta	86.04	0.00e+00	963.00
IUUC-Tni-119999	Tetraodon nigroviridis	88.99	0.00e+00	1078.00
IUUC-Tca-121074	Theobroma cacao	31.43	3.00e-39	156.00
IUUC-Tbe-127987	Tupaia belangeri	95.85	0.00e+00	924.00
IUUC-Ttr-128613	Tursiops truncatus	88.32	0.00e+00	1002.00
IUUC-Xtr-132401	Xenopus tropicalis	91.86	4.00e-171	593.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence