iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023913

Ensembl Protein ID

ENSCSAP00000007004.1

UniProt Accession

A0A0D9REG5; A0A0D9REG5_CHLSB

Genbank Protein ID

ENSCSAP00000007004

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01150186

Gene Name

PIAS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000010838.1	ENSCSAT00000008870.1	ENSCSAP00000007004.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.77	0.00e+00	766.00	IUUC-Hsa-045784

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MAAELVEAKN MVMSFRVSDL QMLLGFVGRS KSGLKHELVT RALQLVQFDC SPELFKKIKE 60
LYETRYAKKN SEPAQQPHRP LDPLTMHSTY DRASAVPRTP LAGPNIDYPV LYGKYLNGLG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCGG AGCTGGTGGA GGCCAAAGTG AGTGAGCGGC GGCGGCACCG GCCGGGGCAA 60
GTGGGCGAGA GGGCGGGGGC CGGGCCGCGG GTTGAGGTCT GCGCCTTCTG TCCGGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027224--PIAS4
IPR023321--PINIT
IPR003034--SAP_dom

PROSITE

PS51466--PINIT
PS50800--SAP

Pfam

PF14324--PINIT

SMART

SM00513--SAP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016363--C:nuclear matrix
GO:0005654--C:nucleoplasm
GO:1990234--C:transferase complex
GO:0003677--F:DNA binding
GO:0061665--F:SUMO ligase activity
GO:0003714--F:transcription corepressor activity
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:1902231--P:positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:1902174--P:positive regulation of keratinocyte apoptotic process
GO:0033235--P:positive regulation of protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001745	Ailuropoda melanoleuca	79.34	0.00e+00	720.00
IUUC-Apl-003765	Anas platyrhynchos	70.53	0.00e+00	646.00
IUUC-Ame-010763	Astyanax mexicanus	49.12	2.00e-102	365.00
IUUC-Bta-012369	Bos taurus	82.21	0.00e+00	742.00
IUUC-Cja-019450	Callithrix jacchus	84.44	0.00e+00	759.00
IUUC-Cfa-020933	Canis familiaris	81.31	0.00e+00	730.00
IUUC-Cpo-022112	Cavia porcellus	79.08	0.00e+00	698.00
IUUC-Dre-027609	Danio rerio	48.65	3.00e-99	355.00
IUUC-Dno-029664	Dasypus novemcinctus	60.98	2.00e-108	386.00
IUUC-Ete-032988	Echinops telfairi	92.74	8.00e-167	580.00
IUUC-Eca-034430	Equus caballus	79.38	0.00e+00	699.00
IUUC-Fca-035968	Felis catus	96.92	2.00e-167	581.00
IUUC-Fal-037449	Ficedula albicollis	71.85	0.00e+00	637.00
IUUC-Gmo-038925	Gadus morhua	49.64	1.00e-97	350.00
IUUC-Gga-040362	Gallus gallus	74.37	0.00e+00	685.00
IUUC-Gac-042353	Gasterosteus aculeatus	48.65	1.00e-90	326.00
IUUC-Ggo-044810	Gorilla gorilla	84.24	0.00e+00	730.00
IUUC-Hsa-045784	Homo sapiens	86.77	0.00e+00	780.00
IUUC-Itr-048486	Ictidomys tridecemlineatus	78.59	0.00e+00	718.00
IUUC-Lch-049727	Latimeria chalumnae	58.98	7.00e-107	380.00
IUUC-Laf-054261	Loxodonta africana	80.92	0.00e+00	734.00
IUUC-Mcc-054931	Macaca mulatta	87.94	0.00e+00	769.00
IUUC-Meu-056468	Macropus eugenii	76.31	0.00e+00	703.00
IUUC-Mga-059981	Meleagris gallopavo	75.47	1.00e-156	545.00
IUUC-Mmr-061181	Microcebus murinus	79.41	0.00e+00	698.00
IUUC-Mdo-062345	Monodelphis domestica	75.92	0.00e+00	706.00
IUUC-Mmu-063197	Mus musculus	75.14	0.00e+00	689.00
IUUC-Mpu-066275	Mustela putorius furo	80.31	0.00e+00	733.00
IUUC-Mlu-067194	Myotis lucifugus	81.50	0.00e+00	739.00
IUUC-Ont-072227	Oreochromis niloticus	48.87	1.00e-96	347.00
IUUC-Ola-086865	Oryzias latipes	48.43	2.00e-95	342.00
IUUC-Oga-088945	Otolemur garnettii	84.08	0.00e+00	763.00
IUUC-Oar-089412	Ovis aries	79.65	0.00e+00	702.00
IUUC-Ptr-091550	Pan troglodytes	72.27	5.00e-140	490.00
IUUC-Pan-092183	Papio anubis	87.74	0.00e+00	783.00
IUUC-Psi-093003	Pelodiscus sinensis	72.43	0.00e+00	665.00
IUUC-Pfo-096704	Poecilia formosa	48.99	6.00e-99	354.00
IUUC-Pab-097923	Pongo abelii	85.07	9.00e-178	615.00
IUUC-Pca-100249	Procavia capensis	61.48	5.00e-95	340.00
IUUC-Pva-102562	Pteropus vampyrus	76.97	0.00e+00	665.00
IUUC-Rno-105762	Rattus norvegicus	76.11	0.00e+00	693.00
IUUC-Sha-107253	Sarcophilus harrisii	75.15	0.00e+00	697.00
IUUC-Sar-113149	Sorex araneus	85.45	8.00e-127	447.00
IUUC-Ssc-115241	Sus scrofa	82.21	0.00e+00	747.00
IUUC-Tgu-116884	Taeniopygia guttata	72.24	0.00e+00	635.00
IUUC-Tru-118031	Takifugu rubripes	49.32	2.00e-102	366.00
IUUC-Tni-119766	Tetraodon nigroviridis	49.33	2.00e-97	349.00
IUUC-Ttr-128556	Tursiops truncatus	71.18	6.00e-164	570.00
IUUC-Xtr-131866	Xenopus tropicalis	66.22	1.00e-173	602.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence