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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046732
Ensembl Protein ID ENSP00000254442.3
UniProt Accession Q9Y4E6; A7E2C8; Q86UX5; Q86VP2; Q96PS7; WDR7_HUMAN
Genbank Protein ID AAM33134.1; AAL03983.1; BAA25467.2; EAW63038.1; AAH50352.1; AAI50283.1
Protein Name WD repeat-containing protein 7; Rabconnectin-3 beta; TGF-beta resistance-associated protein TRAG
Genbank Nucleotide ID AY099325; AF188125; AB011113; CH471096; BC050352; BC150282
Gene Name WDR7; KIAA0541; TRAG
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000091157.13 ENST00000357574.7 ENSP00000350187.2
ENSG00000091157.13 ENST00000254442.7 ENSP00000254442.3
ENSG00000091157.13 ENST00000591449.1 ENSP00000467596.1
ENSG00000091157.13 ENST00000585669.1 ENSP00000466480.1
ENSG00000091157.13 ENST00000615645.4 ENSP00000481823.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDMentha
Disease-associated Variation
GWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProt
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.50e-33 113.8 62 102
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf....sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt+s+tcl+     sd  ++vs+s  g + +WD+++g+++
   Q: 62   GHTASITCLSKacasSDkQYIVSASESGEMCLWDVSDGRCI 102
           8*******9434699999*********************97 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAGNSLVLPI VLWGRKAPTH CISAVLLTDD GATIVTGCHD GQICLWDLSV ELQINPRALL 60
FGHTASITCL SKACASSDKQ YIVSASESGE MCLWDVSDGR CIEFTKLACT HTGIQFYQFS 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046732|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTTGGGGCT GGTGTCAGCT GATTTACTGC AGTGGCGGCG GCGGCGGCAC CGGCACCTTG 60
CAGTATCACT GGGGAGACGG CGGCTGTATA GCGCTTGCCG CCCCACGGAT TATCCCAGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046732|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR011989--ARM-like
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0008021--C:synaptic vesicle
GO:0002244--P:hematopoietic progenitor cell differentiation
KEGG hsa:23335
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000634 Aegilops tauschii 25.31 3.00e-14 74.30
IUUC-Aml-001481 Ailuropoda melanoleuca 97.11 0.00e+00 2864.00
IUUC-Atr-002981 Amborella trichopoda 25.00 8.00e-09 57.00
IUUC-Apl-003943 Anas platyrhynchos 86.52 0.00e+00 1783.00
IUUC-Aca-005145 Anolis carolinensis 88.49 0.00e+00 2616.00
IUUC-Aly-005882 Arabidopsis lyrata 22.36 1.00e-09 60.10
IUUC-Ath-006797 Arabidopsis thaliana 21.53 2.00e-09 58.90
IUUC-Ame-011180 Astyanax mexicanus 72.44 0.00e+00 2127.00
IUUC-Bta-012912 Bos taurus 96.31 0.00e+00 2865.00
IUUC-Bra-018098 Brassica rapa 23.06 1.00e-10 62.40
IUUC-Cel-018565 Caenorhabditis elegans 34.75 3.00e-98 353.00
IUUC-Cja-019970 Callithrix jacchus 97.22 0.00e+00 2741.00
IUUC-Cfa-020677 Canis familiaris 96.98 0.00e+00 2836.00
IUUC-Cpo-021408 Cavia porcellus 97.18 0.00e+00 2857.00
IUUC-Csa-023786 Chlorocebus sabaeus 99.21 0.00e+00 2704.00
IUUC-Cho-024612 Choloepus hoffmanni 95.39 0.00e+00 1198.00
IUUC-Cin-025255 Ciona intestinalis 41.12 0.00e+00 1023.00
IUUC-Csv-026361 Ciona savignyi 41.19 0.00e+00 988.00
IUUC-Cne-026981 Cryptococcus neoformans 26.69 1.00e-20 96.30
IUUC-Dre-027951 Danio rerio 81.01 0.00e+00 1036.00
IUUC-Dno-029072 Dasypus novemcinctus 95.85 0.00e+00 2831.00
IUUC-Dor-030771 Dipodomys ordii 88.47 0.00e+00 1471.00
IUUC-Dme-031768 Drosophila melanogaster 40.38 0.00e+00 792.00
IUUC-Ete-032492 Echinops telfairi 85.09 0.00e+00 2324.00
IUUC-Eca-033496 Equus caballus 97.38 0.00e+00 2878.00
IUUC-Eeu-034689 Erinaceus europaeus 87.79 0.00e+00 727.00
IUUC-Fca-035530 Felis catus 96.91 0.00e+00 2863.00
IUUC-Fal-037238 Ficedula albicollis 81.82 0.00e+00 2282.00
IUUC-Gmo-039528 Gadus morhua 75.94 0.00e+00 2154.00
IUUC-Gga-041043 Gallus gallus 86.49 0.00e+00 2023.00
IUUC-Gac-042524 Gasterosteus aculeatus 77.42 0.00e+00 2224.00
IUUC-Ggo-045112 Gorilla gorilla 99.26 0.00e+00 2922.00
IUUC-Itr-048340 Ictidomys tridecemlineatus 97.42 0.00e+00 958.00
IUUC-Lch-050643 Latimeria chalumnae 84.58 0.00e+00 2048.00
IUUC-Lpe-051544 Leersia perrieri 25.38 1.00e-11 66.20
IUUC-Loc-051774 Lepisosteus oculatus 79.43 0.00e+00 2176.00
IUUC-Laf-054349 Loxodonta africana 96.18 0.00e+00 2823.00
IUUC-Mcc-055800 Macaca mulatta 99.26 0.00e+00 2928.00
IUUC-Meu-056091 Macropus eugenii 91.49 0.00e+00 1762.00
IUUC-Mtr-058676 Medicago truncatula 21.76 1.00e-13 73.20
IUUC-Mga-060096 Meleagris gallopavo 67.27 0.00e+00 1204.00
IUUC-Mmr-061271 Microcebus murinus 97.85 0.00e+00 2861.00
IUUC-Mdo-062622 Monodelphis domestica 93.56 0.00e+00 2759.00
IUUC-Mmu-063262 Mus musculus 94.97 0.00e+00 2781.00
IUUC-Mac-065659 Musa acuminata 25.47 2.00e-08 55.80
IUUC-Mpu-066523 Mustela putorius furo 96.71 0.00e+00 2837.00
IUUC-Mlu-067288 Myotis lucifugus 94.65 0.00e+00 2800.00
IUUC-Nle-069610 Nomascus leucogenys 96.98 0.00e+00 2840.00
IUUC-Opr-070413 Ochotona princeps 87.71 0.00e+00 2559.00
IUUC-Ont-072199 Oreochromis niloticus 78.47 0.00e+00 2259.00
IUUC-Oan-073095 Ornithorhynchus anatinus 93.36 0.00e+00 2773.00
IUUC-Ocu-074257 Oryctolagus cuniculus 97.58 0.00e+00 2880.00
IUUC-Oba-075713 Oryza barthii 26.40 2.00e-12 68.90
IUUC-Obr-076894 Oryza brachyantha 26.29 2.00e-11 65.50
IUUC-Ogl-077521 Oryza glaberrima 26.40 2.00e-12 68.60
IUUC-Ogu-078103 Oryza glumaepatula 26.40 6.00e-12 67.40
IUUC-Oin-080169 Oryza indica 26.40 2.00e-12 68.60
IUUC-Olo-080818 Oryza longistaminata 22.04 3.00e-15 78.20
IUUC-Ome-081902 Oryza meridionalis 26.40 3.00e-12 68.60
IUUC-Oni-082333 Oryza nivara 26.80 3.00e-12 68.20
IUUC-Opu-083952 Oryza punctata 26.90 2.00e-12 68.90
IUUC-Oru-085112 Oryza rufipogon 22.45 6.00e-15 77.40
IUUC-Osa-085615 Oryza sativa 22.25 6.00e-15 76.30
IUUC-Ola-087177 Oryzias latipes 77.37 0.00e+00 2196.00
IUUC-Oga-088290 Otolemur garnettii 96.04 0.00e+00 2859.00
IUUC-Oar-089575 Ovis aries 94.83 0.00e+00 2800.00
IUUC-Ptr-091041 Pan troglodytes 99.53 0.00e+00 2931.00
IUUC-Pan-092048 Papio anubis 99.26 0.00e+00 2925.00
IUUC-Psi-093637 Pelodiscus sinensis 91.21 0.00e+00 2743.00
IUUC-Pma-094714 Petromyzon marinus 64.09 0.00e+00 1094.00
IUUC-Pfo-096529 Poecilia formosa 69.25 0.00e+00 1939.00
IUUC-Pab-098194 Pongo abelii 99.46 0.00e+00 2930.00
IUUC-Pop-099546 Populus trichocarpa 22.14 9.00e-12 67.00
IUUC-Pca-100950 Procavia capensis 93.61 0.00e+00 717.00
IUUC-Ppe-101653 Prunus persica 27.81 2.00e-09 58.90
IUUC-Pva-102803 Pteropus vampyrus 96.12 0.00e+00 2837.00
IUUC-Rno-105904 Rattus norvegicus 93.83 0.00e+00 2753.00
IUUC-Sha-106926 Sarcophilus harrisii 73.95 0.00e+00 1485.00
IUUC-Smo-109304 Selaginella moellendorffii 23.15 8.00e-22 99.80
IUUC-Sit-110049 Setaria italica 26.51 1.00e-11 65.90
IUUC-Sly-111516 Solanum lycopersicum 21.01 3.00e-11 65.10
IUUC-Stu-111982 Solanum tuberosum 21.93 3.00e-10 61.60
IUUC-Sar-113730 Sorex araneus 88.33 0.00e+00 1917.00
IUUC-Sbi-114887 Sorghum bicolor 27.88 2.00e-12 68.60
IUUC-Ssc-116213 Sus scrofa 94.33 0.00e+00 1922.00
IUUC-Tgu-117297 Taeniopygia guttata 85.92 0.00e+00 2602.00
IUUC-Tru-117887 Takifugu rubripes 77.77 0.00e+00 2209.00
IUUC-Tsy-118970 Tarsius syrichta 93.88 0.00e+00 2544.00
IUUC-Tni-119791 Tetraodon nigroviridis 79.08 0.00e+00 1060.00
IUUC-Tca-121391 Theobroma cacao 21.50 4.00e-15 77.80
IUUC-Tae-123628 Triticum aestivum 27.36 2.00e-15 79.00
IUUC-Tur-125959 Triticum urartu 27.36 2.00e-15 78.60
IUUC-Tbe-127847 Tupaia belangeri 90.26 0.00e+00 942.00
IUUC-Ttr-128200 Tursiops truncatus 92.95 0.00e+00 2682.00
IUUC-Vpa-130178 Vicugna pacos 96.82 0.00e+00 2123.00
IUUC-Xtr-132699 Xenopus tropicalis 84.44 0.00e+00 1837.00
IUUC-Xma-133180 Xiphophorus maculatus 77.26 0.00e+00 1439.00
Created Date 25-Jun-2017

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