iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Mmu-064310

Ensembl Protein ID

ENSMUSP00000034986.7

UniProt Accession

Q8BX13; UBE3D_MOUSE

Genbank Protein ID

BAC33623.1; AAI15687.1; AAI15688.1

Protein Name

E3 ubiquitin-protein ligase E3D; HECT-type E3 ubiquitin transferase E3D; UbcH10-binding protein with a HECT-like domain; Ubiquitin-conjugating enzyme E2C-binding protein

Genbank Nucleotide ID

AK049229; BC115686; BC115687

Gene Name

Ube2cbp; Ube3d; H10bh

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000032415.14	ENSMUST00000034986.13	ENSMUSP00000034986.7
ENSMUSG00000032415.14	ENSMUST00000121189.2	ENSMUSP00000113549.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
circBase	microRNA	TRANSFAC	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/HECT	74.29	4.00e-162	568.00	IUUC-Hsa-046938

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Mus musculus

Functional Description
(View)

E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

Protein Sequence
(Fasta)

MAVAAAETRV FLEVRRRLQS ALLILGGPDE GGMHLDISIT PTSLLVRTPD GCTEIRLPAG 60
VRLVPSSCGG LQYISGDGLH LRLRVQAESS PQPISVFNQS LQAQECCTFY CQSCGEVTIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACGGCCGC CGCCGGATCC CTTCGCGCTA CCTTGGCCTG GGAGCCAGCC GCCTGCTACG 60
GCCGCACGTG CTCCCACCCT GTCCGGGTTC TAGTAACTGT GGGCTCGGTC CCGCGTGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-1185--Reference proteome
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway

Interpro

IPR019193--UBQ-conj_enz_E2-bd_prot

Pfam

PF09814--HECT_2

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016740--F:transferase activity
GO:0016567--P:protein ubiquitination

KEGG

mmu:70348

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002283	Ailuropoda melanoleuca	74.22	4.00e-166	577.00
IUUC-Apl-003735	Anas platyrhynchos	63.67	7.00e-94	336.00
IUUC-Ago-007913	Ashbya gossypii	21.27	3.00e-11	62.80
IUUC-Acl-008059	Aspergillus clavatus	24.07	5.00e-05	42.40
IUUC-Ame-011464	Astyanax mexicanus	39.58	4.00e-78	285.00
IUUC-Bgr-012278	Blumeria graminis	24.26	5.00e-07	48.90
IUUC-Bta-013117	Bos taurus	71.72	6.00e-162	563.00
IUUC-Bci-013655	Botrytis cinerea	22.07	1.00e-04	41.20
IUUC-Cel-018650	Caenorhabditis elegans	22.67	2.00e-04	40.80
IUUC-Cja-019652	Callithrix jacchus	73.51	4.00e-138	484.00
IUUC-Cfa-020496	Canis familiaris	76.61	1.00e-175	608.00
IUUC-Cpo-021497	Cavia porcellus	70.12	8.00e-140	489.00
IUUC-Csa-023348	Chlorocebus sabaeus	75.58	1.00e-171	595.00
IUUC-Cho-024538	Choloepus hoffmanni	73.25	3.00e-168	584.00
IUUC-Cin-025117	Ciona intestinalis	26.44	3.00e-24	106.00
IUUC-Csv-026319	Ciona savignyi	27.64	5.00e-25	108.00
IUUC-Dre-028413	Danio rerio	41.01	1.00e-70	259.00
IUUC-Dno-029642	Dasypus novemcinctus	65.17	1.00e-126	445.00
IUUC-Dor-031050	Dipodomys ordii	73.49	2.00e-106	378.00
IUUC-Dse-031533	Dothistroma septosporum	34.21	1.80e-01	30.40
IUUC-Dme-031861	Drosophila melanogaster	26.71	4.00e-05	42.70
IUUC-Ete-032451	Echinops telfairi	64.03	3.00e-125	441.00
IUUC-Eca-034131	Equus caballus	77.89	6.00e-132	463.00
IUUC-Fca-036591	Felis catus	76.62	4.00e-159	553.00
IUUC-Fal-037294	Ficedula albicollis	55.87	5.00e-94	337.00
IUUC-Fox-037718	Fusarium oxysporum	22.25	1.00e-02	34.70
IUUC-Gmo-039559	Gadus morhua	35.93	2.00e-52	199.00
IUUC-Ggr-039897	Gaeumannomyces graminis	30.00	3.00e-03	36.60
IUUC-Gga-040698	Gallus gallus	55.24	8.00e-105	374.00
IUUC-Gac-041989	Gasterosteus aculeatus	37.99	4.00e-64	238.00
IUUC-Ggo-044662	Gorilla gorilla	74.81	6.00e-169	586.00
IUUC-Hsa-046938	Homo sapiens	74.29	1.00e-168	585.00
IUUC-Itr-048017	Ictidomys tridecemlineatus	68.63	1.00e-125	442.00
IUUC-Kpa-049106	Komagataella pastoris	21.17	1.90e-02	33.50
IUUC-Lch-049813	Latimeria chalumnae	48.25	3.00e-87	315.00
IUUC-Loc-052595	Lepisosteus oculatus	42.20	6.00e-81	294.00
IUUC-Lma-053011	Leptosphaeria maculans	32.20	5.00e-05	43.10
IUUC-Laf-054445	Loxodonta africana	73.01	4.00e-165	573.00
IUUC-Mcc-054983	Macaca mulatta	75.32	5.00e-170	590.00
IUUC-Meu-055908	Macropus eugenii	47.11	2.00e-75	276.00
IUUC-Mla-059182	Melampsora laricipopulina	33.75	4.00e-05	43.10
IUUC-Mga-059309	Meleagris gallopavo	50.20	3.00e-65	241.00
IUUC-Mvi-060250	Microbotryum violaceum	22.07	1.00e-08	55.80
IUUC-Mmr-061565	Microcebus murinus	75.06	4.00e-170	590.00
IUUC-Mdo-062560	Monodelphis domestica	63.78	7.00e-138	483.00
IUUC-Mpu-066767	Mustela putorius furo	75.28	2.00e-156	544.00
IUUC-Mlu-068164	Myotis lucifugus	71.69	3.00e-137	481.00
IUUC-Nle-070103	Nomascus leucogenys	75.06	2.00e-169	588.00
IUUC-Opr-070428	Ochotona princeps	66.48	2.00e-132	465.00
IUUC-Ont-071622	Oreochromis niloticus	38.27	2.00e-68	253.00
IUUC-Oan-072809	Ornithorhynchus anatinus	59.21	8.00e-96	343.00
IUUC-Ocu-074517	Oryctolagus cuniculus	73.01	1.00e-161	562.00
IUUC-Ola-086813	Oryzias latipes	38.74	3.00e-58	218.00
IUUC-Oga-087958	Otolemur garnettii	60.66	4.00e-125	441.00
IUUC-Oar-089790	Ovis aries	68.66	3.00e-131	461.00
IUUC-Ptr-091239	Pan troglodytes	75.32	1.00e-170	592.00
IUUC-Pan-092265	Papio anubis	75.58	6.00e-172	596.00
IUUC-Psi-094083	Pelodiscus sinensis	58.64	8.00e-121	426.00
IUUC-Pfo-097062	Poecilia formosa	38.35	3.00e-62	232.00
IUUC-Pab-098283	Pongo abelii	69.15	5.00e-151	526.00
IUUC-Pca-100292	Procavia capensis	59.64	2.00e-122	432.00
IUUC-Pva-103005	Pteropus vampyrus	73.67	2.00e-159	555.00
IUUC-Pgr-103566	Puccinia graminis	33.93	8.00e-04	38.90
IUUC-Pyt-104623	Pyrenophora triticirepentis	22.13	2.00e-01	30.40
IUUC-Rno-105052	Rattus norvegicus	91.58	0.00e+00	698.00
IUUC-Sce-106419	Saccharomyces cerevisiae	20.82	2.00e-05	43.10
IUUC-Sha-107214	Sarcophilus harrisii	58.15	1.00e-101	362.00
IUUC-Sar-112980	Sorex araneus	71.21	6.00e-161	560.00
IUUC-Ssc-115639	Sus scrofa	67.87	1.00e-85	309.00
IUUC-Tgu-117021	Taeniopygia guttata	57.73	2.00e-100	359.00
IUUC-Tru-117965	Takifugu rubripes	39.80	7.00e-72	264.00
IUUC-Tsy-119482	Tarsius syrichta	64.08	9.00e-106	376.00
IUUC-Tni-119773	Tetraodon nigroviridis	40.85	4.00e-53	201.00
IUUC-Tre-121976	Trichoderma reesei	20.20	4.00e-04	38.90
IUUC-Tvi-122374	Trichoderma virens	35.29	8.90e-02	31.60
IUUC-Tme-127047	Tuber melanosporum	24.40	5.00e-05	42.40
IUUC-Tbe-127606	Tupaia belangeri	70.90	5.00e-68	251.00
IUUC-Ttr-128711	Tursiops truncatus	72.24	6.00e-158	550.00
IUUC-Vpa-130345	Vicugna pacos	63.26	6.00e-125	440.00
IUUC-Xtr-132567	Xenopus tropicalis	46.04	4.00e-84	305.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence