iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Opu-084176

Ensembl Protein ID

OPUNC01G11010.1

UniProt Accession

A0A0E0JH14; A0A0E0JH14_ORYPU

Protein Name

Presenilin

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
OPUNC01G11010	OPUNC01G11010.1	OPUNC01G11010.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	30.24	8.00e-31	131.00	IUUC-Cel-018553
UBD/Alpha-Helix/CUE	32.22	4.00e-27	120.00	IUUC-Dre-028689

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryza punctata

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MALVVLLISL LAPPSSPGSA GAAPPPPPVT AATLVYLESP TDTPGQKLVG ALLDAAVFVA 60
LVAVVTFVLV ALYYYRCTCF LKNYMRFSAF FVLFSMGGAI AAAVLRRLGA PLDAATALVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGG TGGTGCTCCT CATCTCCCTC CTCGCGCCGC CCTCCTCCCC GGGGTCCGCG 60
GGTGCCGCGC CGCCGCCGCC GCCGGTCACC GCCGCGACGC TAGTCTACCT CGAGAGCCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0732--Signal
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	78.63	6.00e-121	427.00
IUUC-Aml-001648	Ailuropoda melanoleuca	34.26	5.00e-34	137.00
IUUC-Atr-003039	Amborella trichopoda	55.29	3.00e-102	364.00
IUUC-Apl-003727	Anas platyrhynchos	32.91	3.00e-32	132.00
IUUC-Aca-004582	Anolis carolinensis	33.42	3.00e-33	135.00
IUUC-Aly-005455	Arabidopsis lyrata	51.32	2.00e-95	342.00
IUUC-Ath-006730	Arabidopsis thaliana	51.66	5.00e-96	343.00
IUUC-Ame-011500	Astyanax mexicanus	32.65	2.00e-29	123.00
IUUC-Bta-013026	Bos taurus	31.58	1.00e-30	127.00
IUUC-Bdi-014196	Brachypodium distachyon	80.89	2.00e-149	521.00
IUUC-Bol-015841	Brassica oleracea	53.61	5.00e-91	327.00
IUUC-Bra-017580	Brassica rapa	51.56	2.00e-84	305.00
IUUC-Cel-018553	Caenorhabditis elegans	34.36	1.00e-40	159.00
IUUC-Cja-019994	Callithrix jacchus	33.16	3.00e-32	132.00
IUUC-Cfa-020074	Canis familiaris	33.93	1.00e-33	137.00
IUUC-Cpo-022237	Cavia porcellus	33.50	2.00e-32	132.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	44.32	3.00e-35	142.00
IUUC-Csa-023537	Chlorocebus sabaeus	33.42	8.00e-33	134.00
IUUC-Cho-024735	Choloepus hoffmanni	35.17	5.00e-29	121.00
IUUC-Cin-025780	Ciona intestinalis	33.17	1.00e-38	153.00
IUUC-Csv-025967	Ciona savignyi	39.31	3.00e-22	99.00
IUUC-Dre-028689	Danio rerio	33.16	3.00e-30	125.00
IUUC-Dno-029758	Dasypus novemcinctus	34.19	5.00e-33	134.00
IUUC-Dor-030609	Dipodomys ordii	47.66	5.00e-19	88.60
IUUC-Dme-031929	Drosophila melanogaster	37.64	5.00e-24	105.00
IUUC-Ete-032487	Echinops telfairi	61.73	4.00e-12	65.50
IUUC-Eca-033391	Equus caballus	27.73	1.00e-19	90.50
IUUC-Eeu-035134	Erinaceus europaeus	34.05	4.00e-31	127.00
IUUC-Fca-036243	Felis catus	33.16	7.00e-33	134.00
IUUC-Fal-036600	Ficedula albicollis	32.99	1.00e-32	133.00
IUUC-Gmo-038550	Gadus morhua	35.52	2.00e-25	109.00
IUUC-Gga-040993	Gallus gallus	33.50	2.00e-34	139.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.92	4.00e-34	138.00
IUUC-Gma-043822	Glycine max	85.88	1.00e-39	156.00
IUUC-Ggo-045338	Gorilla gorilla	37.43	1.00e-25	110.00
IUUC-Hsa-046822	Homo sapiens	33.42	8.00e-33	134.00
IUUC-Hvu-047141	Hordeum vulgare	79.65	5.00e-130	457.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	33.24	2.00e-33	135.00
IUUC-Lch-049638	Latimeria chalumnae	34.64	4.00e-24	105.00
IUUC-Lpe-051132	Leersia perrieri	84.96	1.00e-162	565.00
IUUC-Loc-052427	Lepisosteus oculatus	32.16	8.00e-36	144.00
IUUC-Laf-053979	Loxodonta africana	33.33	9.00e-30	124.00
IUUC-Mcc-055682	Macaca mulatta	33.42	8.00e-33	134.00
IUUC-Meu-056004	Macropus eugenii	30.00	1.00e-19	90.50
IUUC-Mtr-058392	Medicago truncatula	54.22	9.00e-97	346.00
IUUC-Mga-059466	Meleagris gallopavo	33.25	4.00e-34	138.00
IUUC-Mmr-060890	Microcebus murinus	36.31	6.00e-25	107.00
IUUC-Mdo-062197	Monodelphis domestica	34.42	3.00e-35	142.00
IUUC-Mmu-063823	Mus musculus	36.87	2.00e-25	109.00
IUUC-Mac-064858	Musa acuminata	67.41	1.00e-45	176.00
IUUC-Mpu-065927	Mustela putorius furo	33.42	5.00e-34	138.00
IUUC-Mlu-067079	Myotis lucifugus	33.42	2.00e-36	145.00
IUUC-Nle-070180	Nomascus leucogenys	33.42	8.00e-33	134.00
IUUC-Opr-070344	Ochotona princeps	35.20	1.00e-22	100.00
IUUC-Ont-071846	Oreochromis niloticus	34.64	6.00e-20	91.70
IUUC-Oan-072783	Ornithorhynchus anatinus	32.93	2.00e-23	102.00
IUUC-Ocu-074527	Oryctolagus cuniculus	33.42	3.00e-33	135.00
IUUC-Oba-075256	Oryza barthii	96.03	3.00e-162	563.00
IUUC-Obr-076302	Oryza brachyantha	87.50	2.00e-165	574.00
IUUC-Ogl-077097	Oryza glaberrima	96.25	2.00e-173	601.00
IUUC-Ogu-078570	Oryza glumaepatula	96.00	4.00e-173	600.00
IUUC-Oin-079244	Oryza indica	96.00	4.00e-173	600.00
IUUC-Olo-080484	Oryza longistaminata	94.83	1.00e-125	441.00
IUUC-Ome-081814	Oryza meridionalis	95.27	4.00e-174	603.00
IUUC-Oni-082057	Oryza nivara	96.00	5.00e-173	600.00
IUUC-Oru-084618	Oryza rufipogon	96.00	3.00e-173	600.00
IUUC-Osa-085602	Oryza sativa	96.03	9.00e-175	605.00
IUUC-Ola-086707	Oryzias latipes	34.81	1.00e-25	109.00
IUUC-Olu-087811	Ostreococcus lucimarinus	38.94	3.00e-36	145.00
IUUC-Oga-088560	Otolemur garnettii	36.31	3.00e-25	108.00
IUUC-Oar-090348	Ovis aries	32.65	3.00e-35	142.00
IUUC-Ptr-091060	Pan troglodytes	33.42	8.00e-33	134.00
IUUC-Pan-091742	Papio anubis	37.43	6.00e-26	111.00
IUUC-Psi-093505	Pelodiscus sinensis	32.48	3.00e-33	135.00
IUUC-Pma-094612	Petromyzon marinus	31.22	5.00e-21	95.10
IUUC-Ppa-095431	Physcomitrella patens	44.80	2.00e-83	302.00
IUUC-Pfo-097396	Poecilia formosa	32.59	6.00e-35	141.00
IUUC-Pab-098591	Pongo abelii	33.42	6.00e-33	134.00
IUUC-Pop-099661	Populus trichocarpa	47.37	6.00e-77	280.00
IUUC-Pca-101120	Procavia capensis	34.08	3.00e-21	95.90
IUUC-Ppe-101495	Prunus persica	52.41	1.00e-100	359.00
IUUC-Pva-102934	Pteropus vampyrus	34.08	3.00e-23	102.00
IUUC-Rno-106052	Rattus norvegicus	36.31	4.00e-25	108.00
IUUC-Sha-106876	Sarcophilus harrisii	33.50	8.00e-35	140.00
IUUC-Smo-109325	Selaginella moellendorffii	44.06	2.00e-59	221.00
IUUC-Sit-110624	Setaria italica	81.60	8.00e-139	486.00
IUUC-Sly-110865	Solanum lycopersicum	87.14	2.00e-32	130.00
IUUC-Stu-112433	Solanum tuberosum	54.70	5.00e-90	324.00
IUUC-Sar-113169	Sorex araneus	41.12	7.00e-19	87.80
IUUC-Sbi-114305	Sorghum bicolor	81.08	3.00e-143	501.00
IUUC-Ssc-115766	Sus scrofa	32.90	5.00e-32	131.00
IUUC-Tgu-116469	Taeniopygia guttata	32.31	3.00e-30	125.00
IUUC-Tru-117732	Takifugu rubripes	32.16	6.00e-31	128.00
IUUC-Tsy-119624	Tarsius syrichta	35.29	3.00e-20	92.40
IUUC-Tni-119852	Tetraodon nigroviridis	31.84	1.00e-18	87.00
IUUC-Tca-121865	Theobroma cacao	55.21	9.00e-103	366.00
IUUC-Tae-123984	Triticum aestivum	79.35	4.00e-128	450.00
IUUC-Tur-126237	Triticum urartu	78.36	5.00e-124	436.00
IUUC-Tbe-127632	Tupaia belangeri	37.43	7.00e-26	110.00
IUUC-Ttr-128793	Tursiops truncatus	32.77	7.00e-31	127.00
IUUC-Vpa-130625	Vicugna pacos	40.00	5.00e-18	85.10
IUUC-Vvi-131312	Vitis vinifera	53.66	6.00e-99	353.00
IUUC-Xtr-132756	Xenopus tropicalis	32.00	1.00e-32	133.00
IUUC-Xma-133377	Xiphophorus maculatus	31.91	7.00e-33	134.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence