iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106667

Ensembl Protein ID

ENSSHAP00000013067.1

UniProt Accession

G3WCB2; G3WCB2_SARHA

Genbank Protein ID

ENSSHAP00000013067

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01152293

Gene Name

FAF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011175.1	ENSSHAT00000013173.1	ENSSHAP00000013067.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/UBX	4.40e-20	72.2	470	547
ULD/UDP/UBQ/UBQ_Other	4.90e-11	42.5	12	71

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfveyllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllve 80
           t++ ++l+iR+p+G++l+r+F +s +l+ +++fv+ ++++++d+F+L+s+fPrr++++ + +++l e +L+p+++l++e
   Q: 470  TEPVSKLRIRTPSGEFLERRFLASSQLRVVFDFVA-SKGFPWDEFKLLSTFPRRDVTQLDPNKSLLEVKLFPQETLFLE 547
           5669*******************************.****************************************986 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL...eddktLadyglkdgstihll 70
           + ++ ++ s+tV+e+K+ +e +l ip   +++++kG      ed   L+ ++l+ ++ +++l
   Q: 12   NVDVVLEDSCTVGEIKQILENELQIP--VSKMLLKGWKTgdvEDSTVLKTLHLPKNNSLYVL 71
           5566678999****************..55899997776677**************999987 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MLDFRVEYRD RNVDVVLEDS CTVGEIKQIL ENELQIPVSK MLLKGWKTGD VEDSTVLKTL 60
HLPKNNSLYV LTPDLPPPSS SHAGALQESL NQNFMLIVTH REVQREYSLN FSGSSTIQEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTGTACTG GCATCGAAAA CATTGATGAA GCCATTACGT TGCTTGAACA GAATAACTGG 60
GACTTGGTGG TAAGTGCTTC ACTGTTTCCA GAATGTCTTG GCAACACTTA AATGTTAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR033043--FAF1_UBX
IPR012336--Thioredoxin-like_fold
IPR006577--UAS
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50033--UBX

Pfam

PF00789--UBX

SMART

SM00594--UAS
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0005635--C:nuclear envelope
GO:0048471--C:perinuclear region of cytoplasm
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008219--P:cell death
GO:0007253--P:cytoplasmic sequestering of NF-kappaB
GO:1902043--P:positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0031334--P:positive regulation of protein complex assembly
GO:0030155--P:regulation of cell adhesion
GO:0042176--P:regulation of protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002153	Ailuropoda melanoleuca	93.47	0.00e+00	1019.00
IUUC-Apl-004127	Anas platyrhynchos	93.27	0.00e+00	1035.00
IUUC-Aca-005188	Anolis carolinensis	91.11	0.00e+00	999.00
IUUC-Ame-010696	Astyanax mexicanus	77.68	0.00e+00	753.00
IUUC-Bta-012965	Bos taurus	93.28	0.00e+00	1016.00
IUUC-Cel-018420	Caenorhabditis elegans	28.53	6.00e-29	122.00
IUUC-Cja-019128	Callithrix jacchus	93.47	0.00e+00	1019.00
IUUC-Cfa-021201	Canis familiaris	90.42	0.00e+00	854.00
IUUC-Cpo-021475	Cavia porcellus	92.27	0.00e+00	837.00
IUUC-Csa-024076	Chlorocebus sabaeus	93.10	0.00e+00	1014.00
IUUC-Cho-025067	Choloepus hoffmanni	78.22	0.00e+00	871.00
IUUC-Cin-025663	Ciona intestinalis	43.50	2.00e-69	255.00
IUUC-Csv-025894	Ciona savignyi	35.71	1.00e-62	233.00
IUUC-Dre-027508	Danio rerio	78.36	0.00e+00	836.00
IUUC-Dno-029336	Dasypus novemcinctus	92.92	0.00e+00	1017.00
IUUC-Dor-030218	Dipodomys ordii	88.20	0.00e+00	936.00
IUUC-Dme-031581	Drosophila melanogaster	36.22	1.00e-85	310.00
IUUC-Ete-032860	Echinops telfairi	69.17	5.00e-148	518.00
IUUC-Eca-034321	Equus caballus	92.92	0.00e+00	981.00
IUUC-Eeu-034844	Erinaceus europaeus	69.49	2.00e-100	360.00
IUUC-Fca-036575	Felis catus	92.02	0.00e+00	688.00
IUUC-Fal-037128	Ficedula albicollis	93.09	0.00e+00	1033.00
IUUC-Gmo-038694	Gadus morhua	76.95	0.00e+00	844.00
IUUC-Gga-040826	Gallus gallus	93.09	0.00e+00	1036.00
IUUC-Gac-042125	Gasterosteus aculeatus	76.41	0.00e+00	868.00
IUUC-Ggo-045254	Gorilla gorilla	93.28	0.00e+00	1019.00
IUUC-Hsa-046722	Homo sapiens	93.10	0.00e+00	1017.00
IUUC-Itr-048149	Ictidomys tridecemlineatus	90.23	9.00e-96	342.00
IUUC-Lch-050312	Latimeria chalumnae	85.49	1.00e-169	588.00
IUUC-Loc-051990	Lepisosteus oculatus	84.21	0.00e+00	854.00
IUUC-Laf-054375	Loxodonta africana	92.31	0.00e+00	691.00
IUUC-Mcc-054627	Macaca mulatta	93.10	0.00e+00	1014.00
IUUC-Meu-056611	Macropus eugenii	98.60	1.00e-111	396.00
IUUC-Mga-059400	Meleagris gallopavo	92.91	0.00e+00	1033.00
IUUC-Mmr-060882	Microcebus murinus	92.92	0.00e+00	999.00
IUUC-Mdo-061874	Monodelphis domestica	98.91	0.00e+00	1103.00
IUUC-Mmu-063444	Mus musculus	92.20	0.00e+00	1010.00
IUUC-Mpu-065713	Mustela putorius furo	93.28	0.00e+00	1018.00
IUUC-Mlu-068122	Myotis lucifugus	91.29	0.00e+00	984.00
IUUC-Nle-069025	Nomascus leucogenys	92.74	0.00e+00	1007.00
IUUC-Opr-071089	Ochotona princeps	82.76	0.00e+00	920.00
IUUC-Ont-072421	Oreochromis niloticus	77.86	0.00e+00	847.00
IUUC-Oan-073092	Ornithorhynchus anatinus	94.80	0.00e+00	840.00
IUUC-Ola-086497	Oryzias latipes	78.91	0.00e+00	853.00
IUUC-Oga-088854	Otolemur garnettii	92.74	0.00e+00	1030.00
IUUC-Oar-090120	Ovis aries	93.10	0.00e+00	996.00
IUUC-Ptr-091554	Pan troglodytes	93.28	0.00e+00	1019.00
IUUC-Pan-091985	Papio anubis	92.92	0.00e+00	995.00
IUUC-Psi-093548	Pelodiscus sinensis	93.82	0.00e+00	1006.00
IUUC-Pma-094123	Petromyzon marinus	52.24	1.00e-52	199.00
IUUC-Pfo-096729	Poecilia formosa	78.58	0.00e+00	854.00
IUUC-Pab-097810	Pongo abelii	93.28	0.00e+00	1019.00
IUUC-Pca-101079	Procavia capensis	83.87	0.00e+00	851.00
IUUC-Pva-102534	Pteropus vampyrus	84.32	0.00e+00	739.00
IUUC-Rno-105127	Rattus norvegicus	92.01	0.00e+00	976.00
IUUC-Sce-106395	Saccharomyces cerevisiae	23.03	3.70e-02	33.10
IUUC-Sar-113424	Sorex araneus	78.89	0.00e+00	627.00
IUUC-Ssc-115974	Sus scrofa	93.83	0.00e+00	1021.00
IUUC-Tgu-116495	Taeniopygia guttata	93.09	0.00e+00	1035.00
IUUC-Tru-118727	Takifugu rubripes	76.04	0.00e+00	832.00
IUUC-Tsy-118906	Tarsius syrichta	89.84	0.00e+00	937.00
IUUC-Tni-119717	Tetraodon nigroviridis	77.50	0.00e+00	843.00
IUUC-Tbe-127849	Tupaia belangeri	79.40	2.00e-161	561.00
IUUC-Ttr-128660	Tursiops truncatus	89.11	0.00e+00	962.00
IUUC-Vpa-130359	Vicugna pacos	93.65	0.00e+00	1022.00
IUUC-Xtr-132212	Xenopus tropicalis	84.10	0.00e+00	717.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence