iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023285

Ensembl Protein ID

ENSCSAP00000000958.1

UniProt Accession

A0A0D9QX69; A0A0D9QX69_CHLSB

Genbank Protein ID

ENSCSAP00000000958

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01085236

Gene Name

USP47

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004651.1	ENSCSAT00000002659.1	ENSCSAP00000000958.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-75	254.8	168	542

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +Gl N+  tCY+NS+LQ+L+++pe+r++l +    +++e++ ++p +++  +lq+lf  l++skk+a++++++++++++ ++e    +q
   Q: 168  VGLVNQAMTCYLNSLLQTLFMTPEFRNALYK---WEFEESE-EDPVTSIPYQLQRLFVLLQTSKKRAIETTDVTRSFGWDSSE--AWQQ 250
           6******************************...5555443.5899*********************************9998..9*** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +D+qE++++++d+le++                           k++++ +li++l+qg+lk+ ++clec+ +  r ++ ld++l ++ 
   Q: 251  HDVQELCRVMFDALEQKW--------------------------KQTEQADLINELYQGKLKDYVRCLECGYEGWRIDTYLDIPLVIRP 313
           ******************..........................678999*************************************95 PP
   S: 179  ke.etkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfct 266
              +++  s++++L++f ++e l+g n+y+ce+ckkk++a+k l++ ++P  L+l+LkRf f+ ++++r+k+n++++fp+eLd+s f  
   Q: 314  YGsSQAFASVEEALHAFIQPEILDGPNQYFCERCKKKCDARKGLRFLHFPYLLTLQLKRFDFDYTTMHRIKLNDRMTFPEELDMSTFID 402
           54045678******************************************************************************999 PP
   S: 267  speekqke.....................................................kkkYeLiavvvHsGslssGHYvayvkne 302
            ++ek+ +                                                     + +YeL++v+vHsGs+ +GHY+a++k+ 
   Q: 403  VEDEKSPQtesctdsgaenegschsdqmsndfsnddgvdegicletnsgtekisksgleknSLIYELFSVMVHSGSAAGGHYYACIKSF 491
           9777666678888888888888889999999999999999999999999999999999999***************************6 PP
   S: 303  kgk.WllfdDskVtevkeeevleetg................staYvlfYk 336
           +++ W+ f+D++V+ +++e++++++g                ++aY+l+Y+
   Q: 492  SDEqWYSFNDQHVSRITQEDIKKTHGgssgsrgyyssafassTNAYMLIYR 542
           5555*******************888************************8 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MVPGEENQLV PKEIENAAEE PRVLCIIQDT TNSKTVNERI TLNLPASTPV RKLFEDVANK 60
VGYINGTFDL VWGNGINTAD MAPLDHTSDK SLLDANFEPG KKNFLHLTDK DGEQPQILLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGTGTCT GAGGCCCAGG GTGAGGCCTC CGCGATTGCT GGAGCGCAGG CGGCGGAGAG 60
GATGACTGCC GTTGCCATTC TCTCTTGAGC TAGCAAGCCG CCGCCACCCT CCAGCCTCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005737--C:cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0006284--P:base-excision repair
GO:0034644--P:cellular response to UV
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010972--P:negative regulation of G2/M transition of mitotic cell cycle
GO:1902230--P:negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0030307--P:positive regulation of cell growth
GO:0042493--P:response to drug
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002228	Ailuropoda melanoleuca	96.81	0.00e+00	2499.00
IUUC-Apl-003486	Anas platyrhynchos	90.69	0.00e+00	2336.00
IUUC-Aca-005061	Anolis carolinensis	87.06	0.00e+00	2363.00
IUUC-Ame-011206	Astyanax mexicanus	80.45	0.00e+00	2081.00
IUUC-Bta-012942	Bos taurus	97.54	0.00e+00	2537.00
IUUC-Cel-018600	Caenorhabditis elegans	37.62	4.00e-123	436.00
IUUC-Cja-018950	Callithrix jacchus	99.61	0.00e+00	2412.00
IUUC-Cfa-020299	Canis familiaris	98.51	0.00e+00	2552.00
IUUC-Cpo-021943	Cavia porcellus	97.47	0.00e+00	2507.00
IUUC-Cho-025006	Choloepus hoffmanni	89.49	0.00e+00	2203.00
IUUC-Cin-025145	Ciona intestinalis	41.45	0.00e+00	732.00
IUUC-Csv-025839	Ciona savignyi	49.47	7.00e-166	578.00
IUUC-Dre-027959	Danio rerio	79.86	0.00e+00	2031.00
IUUC-Dno-030023	Dasypus novemcinctus	95.17	0.00e+00	2394.00
IUUC-Dor-030994	Dipodomys ordii	97.72	0.00e+00	966.00
IUUC-Dme-031604	Drosophila melanogaster	49.39	2.00e-148	520.00
IUUC-Ete-032596	Echinops telfairi	81.30	0.00e+00	1313.00
IUUC-Eca-033913	Equus caballus	98.07	0.00e+00	2543.00
IUUC-Eeu-034518	Erinaceus europaeus	90.19	0.00e+00	2149.00
IUUC-Fca-035997	Felis catus	98.29	0.00e+00	2543.00
IUUC-Fal-037088	Ficedula albicollis	89.89	0.00e+00	2109.00
IUUC-Gmo-038920	Gadus morhua	76.22	0.00e+00	1969.00
IUUC-Gga-040953	Gallus gallus	88.59	0.00e+00	2343.00
IUUC-Gac-042400	Gasterosteus aculeatus	78.54	0.00e+00	2023.00
IUUC-Ggo-044820	Gorilla gorilla	96.95	0.00e+00	2509.00
IUUC-Hsa-046634	Homo sapiens	98.25	0.00e+00	2568.00
IUUC-Lch-050440	Latimeria chalumnae	85.02	0.00e+00	2274.00
IUUC-Loc-051904	Lepisosteus oculatus	83.56	0.00e+00	2202.00
IUUC-Laf-053760	Loxodonta africana	95.57	0.00e+00	2555.00
IUUC-Mcc-054637	Macaca mulatta	98.55	0.00e+00	2578.00
IUUC-Meu-056904	Macropus eugenii	95.49	0.00e+00	1696.00
IUUC-Mga-059556	Meleagris gallopavo	89.06	0.00e+00	2310.00
IUUC-Mmr-061192	Microcebus murinus	97.60	0.00e+00	2553.00
IUUC-Mdo-061929	Monodelphis domestica	94.47	0.00e+00	2499.00
IUUC-Mmu-063726	Mus musculus	93.24	0.00e+00	2496.00
IUUC-Mpu-066014	Mustela putorius furo	98.44	0.00e+00	2552.00
IUUC-Mlu-067232	Myotis lucifugus	97.55	0.00e+00	2511.00
IUUC-Nle-069619	Nomascus leucogenys	99.70	0.00e+00	2584.00
IUUC-Opr-070224	Ochotona princeps	93.43	0.00e+00	1147.00
IUUC-Ont-071384	Oreochromis niloticus	79.58	0.00e+00	2053.00
IUUC-Oan-073208	Ornithorhynchus anatinus	88.95	0.00e+00	2350.00
IUUC-Ocu-074285	Oryctolagus cuniculus	97.09	0.00e+00	2543.00
IUUC-Ola-087051	Oryzias latipes	78.30	0.00e+00	1975.00
IUUC-Oga-088928	Otolemur garnettii	98.36	0.00e+00	2528.00
IUUC-Oar-090215	Ovis aries	97.92	0.00e+00	2543.00
IUUC-Ptr-091035	Pan troglodytes	98.40	0.00e+00	2573.00
IUUC-Pan-092377	Papio anubis	99.40	0.00e+00	2540.00
IUUC-Pfo-096722	Poecilia formosa	79.22	0.00e+00	2041.00
IUUC-Pab-098723	Pongo abelii	98.11	0.00e+00	2566.00
IUUC-Pca-100105	Procavia capensis	92.63	0.00e+00	2316.00
IUUC-Pva-102514	Pteropus vampyrus	98.48	0.00e+00	917.00
IUUC-Rno-105384	Rattus norvegicus	94.40	0.00e+00	2466.00
IUUC-Sha-106982	Sarcophilus harrisii	93.51	0.00e+00	2506.00
IUUC-Sar-113723	Sorex araneus	86.90	0.00e+00	934.00
IUUC-Ssc-115671	Sus scrofa	97.97	0.00e+00	2052.00
IUUC-Tgu-116722	Taeniopygia guttata	88.62	0.00e+00	2295.00
IUUC-Tru-118380	Takifugu rubripes	76.81	0.00e+00	2037.00
IUUC-Tsy-119646	Tarsius syrichta	91.81	0.00e+00	2315.00
IUUC-Tni-120762	Tetraodon nigroviridis	77.19	0.00e+00	2047.00
IUUC-Tbe-127861	Tupaia belangeri	95.92	0.00e+00	2379.00
IUUC-Ttr-129254	Tursiops truncatus	92.16	0.00e+00	1459.00
IUUC-Vpa-130141	Vicugna pacos	98.36	0.00e+00	1151.00
IUUC-Xtr-132700	Xenopus tropicalis	81.94	0.00e+00	2169.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence