iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004759

UUCD1 version

UUC-AnC-00507

Ensembl Protein ID

ENSACAP00000003099.2

UniProt Accession

G1KBM5; G1KBM5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

WDR37

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003155.3	ENSACAT00000003178.3	ENSACAP00000003099.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-23	82.0	366	397
UBD/Beta-Prp	2.00e-45	155.2	279	487

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 366  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 397
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++ +t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 279  KSHQGVVIAADWLVGGKQAVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 367
           456667777999999999**********************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++          +d++vn ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 368  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPI-ATIRTDSAVNRINVCVGQRIIALPHDNRQVRLFDMsgvRLARLPRSNRQGH 454
           ******99999.********************99887.555556666777666669*****************777778888888888* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 455  RRMVCCSAWSEDHplCNLFTCGFDRQAIGWNIN 487
           ************9777899***********986 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPTESGSCAT ARQAKQKRKS HSLSIRRTNS SEQERSGLQR EMLEGQDSKL PSSVRNTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AAEGQTIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCTTCCACA GATATATAAA CCCTATTTGC ATAGTTTTCC AACAGACCTC ACAACCTCTG 60
AGGATGCCTG TCATAGATGT AGGCGAAACG TCAGGAAAGA ATGCTTTTGA AACATGGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

acs:100559399

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	91.94	0.00e+00	922.00
IUUC-Apl-003647	Anas platyrhynchos	95.96	0.00e+00	957.00
IUUC-Ame-011103	Astyanax mexicanus	56.35	9.00e-145	506.00
IUUC-Bta-012718	Bos taurus	91.33	0.00e+00	917.00
IUUC-Cel-018499	Caenorhabditis elegans	41.58	1.00e-93	337.00
IUUC-Cja-019492	Callithrix jacchus	92.73	0.00e+00	947.00
IUUC-Cfa-020199	Canis familiaris	91.33	0.00e+00	934.00
IUUC-Cpo-022500	Cavia porcellus	86.90	0.00e+00	885.00
IUUC-Csa-023567	Chlorocebus sabaeus	93.54	0.00e+00	952.00
IUUC-Cho-025071	Choloepus hoffmanni	67.07	3.00e-178	617.00
IUUC-Cin-025460	Ciona intestinalis	46.60	6.00e-105	374.00
IUUC-Csv-026042	Ciona savignyi	46.12	9.00e-107	380.00
IUUC-Dre-028214	Danio rerio	82.04	0.00e+00	859.00
IUUC-Dno-029826	Dasypus novemcinctus	94.22	0.00e+00	796.00
IUUC-Dor-030967	Dipodomys ordii	92.70	0.00e+00	846.00
IUUC-Dme-031936	Drosophila melanogaster	49.05	9.00e-119	420.00
IUUC-Ete-032452	Echinops telfairi	90.91	0.00e+00	915.00
IUUC-Eca-033278	Equus caballus	91.53	0.00e+00	934.00
IUUC-Eeu-034592	Erinaceus europaeus	80.00	0.00e+00	783.00
IUUC-Fca-036431	Felis catus	92.15	0.00e+00	938.00
IUUC-Fal-037149	Ficedula albicollis	95.35	0.00e+00	955.00
IUUC-Gmo-038476	Gadus morhua	81.28	0.00e+00	782.00
IUUC-Gga-041099	Gallus gallus	96.36	0.00e+00	964.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.80	0.00e+00	813.00
IUUC-Ggo-044683	Gorilla gorilla	85.66	0.00e+00	855.00
IUUC-Hsa-046658	Homo sapiens	93.13	0.00e+00	942.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	93.63	0.00e+00	876.00
IUUC-Lch-050571	Latimeria chalumnae	86.31	0.00e+00	883.00
IUUC-Loc-052652	Lepisosteus oculatus	83.37	0.00e+00	862.00
IUUC-Laf-053712	Loxodonta africana	92.18	0.00e+00	935.00
IUUC-Mcc-055521	Macaca mulatta	93.54	0.00e+00	952.00
IUUC-Meu-056324	Macropus eugenii	91.11	0.00e+00	897.00
IUUC-Mga-060114	Meleagris gallopavo	96.17	0.00e+00	960.00
IUUC-Mmr-061176	Microcebus murinus	92.93	0.00e+00	946.00
IUUC-Mdo-061888	Monodelphis domestica	95.16	0.00e+00	928.00
IUUC-Mmu-063977	Mus musculus	93.55	0.00e+00	951.00
IUUC-Mpu-066220	Mustela putorius furo	78.34	3.00e-165	573.00
IUUC-Mlu-068155	Myotis lucifugus	92.34	0.00e+00	943.00
IUUC-Nle-069964	Nomascus leucogenys	93.33	0.00e+00	950.00
IUUC-Opr-070925	Ochotona princeps	90.55	4.00e-138	484.00
IUUC-Ont-071317	Oreochromis niloticus	87.10	0.00e+00	842.00
IUUC-Oan-072952	Ornithorhynchus anatinus	95.56	0.00e+00	954.00
IUUC-Ocu-073913	Oryctolagus cuniculus	93.55	0.00e+00	951.00
IUUC-Ola-087024	Oryzias latipes	84.91	0.00e+00	879.00
IUUC-Oga-087945	Otolemur garnettii	92.54	0.00e+00	946.00
IUUC-Oar-089854	Ovis aries	91.53	0.00e+00	918.00
IUUC-Ptr-091486	Pan troglodytes	93.33	0.00e+00	945.00
IUUC-Pan-091738	Papio anubis	93.54	0.00e+00	952.00
IUUC-Psi-093953	Pelodiscus sinensis	96.57	0.00e+00	962.00
IUUC-Pma-094560	Petromyzon marinus	74.85	0.00e+00	780.00
IUUC-Pfo-097222	Poecilia formosa	84.24	0.00e+00	822.00
IUUC-Pab-098778	Pongo abelii	89.09	0.00e+00	888.00
IUUC-Pca-100852	Procavia capensis	89.70	0.00e+00	894.00
IUUC-Pva-103130	Pteropus vampyrus	91.67	5.00e-130	457.00
IUUC-Rno-105848	Rattus norvegicus	84.48	0.00e+00	833.00
IUUC-Sha-106750	Sarcophilus harrisii	95.56	0.00e+00	956.00
IUUC-Sar-113749	Sorex araneus	84.24	0.00e+00	835.00
IUUC-Ssc-115691	Sus scrofa	90.51	0.00e+00	912.00
IUUC-Tgu-117365	Taeniopygia guttata	94.75	0.00e+00	911.00
IUUC-Tru-117595	Takifugu rubripes	84.68	0.00e+00	828.00
IUUC-Tsy-118973	Tarsius syrichta	71.35	1.00e-139	489.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.94	0.00e+00	862.00
IUUC-Tbe-127976	Tupaia belangeri	69.29	0.00e+00	653.00
IUUC-Ttr-128472	Tursiops truncatus	89.49	0.00e+00	903.00
IUUC-Xtr-132621	Xenopus tropicalis	92.53	0.00e+00	902.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence