iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011144

Ensembl Protein ID

ENSAMXP00000003057.1

UniProt Accession

W5K646; W5K646_ASTMX

Genbank Protein ID

ENSAMXP00000003057

Protein Name

SUMO-conjugating enzyme

Genbank Nucleotide ID

APWO01047433

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000002986.1	ENSAMXT00000003057.1	ENSAMXP00000003057.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	3.90e-46	156.5	9	127

Active Site

Position(s)	Description	Evidence
71	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 20   kpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvllsiqsl 108
           +p+   +l++we++i G+++tp+egg+Fkl++ f++dYP++PPk+kf+ ++fhPnvy++G+vClsil+e+++W+pa++++++ll+iq+l
   Q: 9    NPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQEL 97
           5677789********************************************************************************** PP
   S: 109  laepnpesplneeaaellkknreeykkkvr 138
           l+epn+++p+++ea++++++nr ey+k+vr
   Q: 98   LNEPNIQDPAQAEAYTIYCQNRVEYEKRVR 127
           ****************************98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

GFVAVPTKNP DGTMNLMNWE CAIPGKKGTP WEGGLFKLRM LFKDDYPSSP PKCKFEPPLF 60
HPNVYPSGTV CLSILEEDKD WRPAITIKQI LLGIQELLNE PNIQDPAQAE AYTIYCQNRV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGCTGCAC CAACCTTGTG TTCTAATTTA CTAGCTAGCT AAATAACCAG TTCTTGGTTC 60
TGTCGTCAAT ATAGTGGCAG CTGTATATAT TATATCATGT GATTTTAGGT AGAATGTTAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR027230--Ubc9
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding
GO:0019789--F:SUMO transferase activity
GO:0060216--P:definitive hemopoiesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000510	Aegilops tauschii	64.76	1.00e-38	151.00
IUUC-Ome-081988	Oryza meridionalis	63.70	4.00e-49	187.00
IUUC-Ttr-128280	Tursiops truncatus	100.00	3.00e-48	182.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence